cell Flashcards
what is the structure of dna?
purine base A & T
Pyramidine C & G
3 part building blocks:
deoxyribose (5carbonsugar), phospahet group, nitrogenous base
whats a nucelotide?
a base, sugar ans phosphate griou are called nucleotide
What are the RNA structure?
RNA contains a sugar ribose which doffers from DNA by the presens of a -OH group.
Uracil pares with Thymine
RNA is single stranded
What are the classes of RNA?
Transfer RNA - carries aminoacids to ribosome
Ribosomal RNA - protein synthesis
Messenger RNA - carry protein from cell’s nucleus to the cell’s cytoplasm
Catalytic RNA - selfsplicing molecules also calles RIBOZYMES
Atisense RNA - recognition rna activates RNA with enzym
What are the stages of DNA replication?
G1 - RNA and protein synthesis
S - DNA replication
G2 - RNA and protein synthesis
M - cell division
Function of helicase?
Open/ unwind the DNA (breaking hydrogen bonds between nitrogenous base pairs)
What is Topoisomerase fuction?
Prevents DNA from supercoiling, works at a region ahead of the replication fork
Function of primase?
Startingpoint of replication.
Synthesis RNA primers complimentary to the DNA strand
Function of DNA polymerase III?
adding to the 3’ end in order to build new DNA
Function of DNA polymerase I?
Removes RNA primers and replace with DNA
Function of DNA ligase?
Seals the gap between DNA fragments
What’s the difference in replication between euaryotes and prokaryotes?
DNA replications only occurs at one site in Prokaryotes .
In eukaryotes multiple sites
What is nuclear envelope function?
Double membrane, forms a selective permable barrier between nuclear and cytoplasmic components.
Outermembrane binds to ribosomes and RER
Function of nuclear lamina?
Supports the nuclear envelope with protein called lamins
What is nuceoplasm?
A gel-like matrix in which the nuclear components are suspended in
What are the stages of translation?
Activation
Initation- Ribosomal subunits binds to mRNA
Elongation- ribosomes moves along mRNA moecule linking aminoacids and forming peptide chain.
Termintion - ribosome reaches a stopcodon which terminates protein synstesis and realises ribosome
What are the two forms of chromatin?
Euchromarin - less condense, can be transcripted
Heterochomatin - condensed, van not be transkripted
What is Transponosos?
A prices of DNA that moves readily from one side to another either whit in or between BACTERIAL DNA
Can code for drug resistant
What is plasmids?
A small circular DNA molecule find in bacteria
What is a prokaryote?
An organism characherized by the absence of nucleus or any menbrande bound organells
What is a nucleosome?
A section of DNA that is wrapped around a core of proteins inside the nucleus.