Celiac Disease

Question 1

Coeliac disease is an _____________ condition which is associated with chronic inflammation of the small intestine

Answer 1

autoimmune

Question 2

Coeliac disease is an autoimmune condition which is associated with chronic inflammation of the ______________

Answer 2

small intestine

Question 3

In celiac disease, dietary proteins known as _____________, which are present in wheat, barley and rye, activate an abnormal immune response in the intestinal mucosa, which can lead to malabsorption of nutrients.

Answer 3

gluten

Question 4

Dietary proteins known as gluten, which are present in ____________, __________, and __________, activate an abnormal immune response in the intestinal mucosa, which can lead to malabsorption of nutrients.

Answer 4

wheat

barley

rye

Question 5

Dietary proteins known as gluten, which are present in wheat, barley and rye, activate an abnormal immune response in the intestinal mucosa, which can lead to ________________ of nutrients.

Answer 5

malabsorption

Question 6

The management of celiac disease is aimed at eliminating symptoms (such as ____________, ____________, and ______________) and reducing the risk of complications, including those resulting from _____________.

Answer 6

diarrhoea
bloating
abdominal pain

malabsorption

Question 7

The only effective treatment for coeliac disease is _________________

Answer 7

a strict, life-long, gluten-free diet

Question 8

What is the drug treatment for patients with celiac disease?

Answer 8

Supplementation of key nutrients IF dietary intake is insufficient eg

• calcium
• vit D

*Initiation of supplementation should involve a discussion with a member of the patient’s healthcare team in order to identify the individual needs of the patient and to allow for appropriate ongoing monitoring

Question 9

Patients who have coeliac disease should be advised not to self-medicate with _______________

Answer 9

over-the-counter vitamins or mineral supplements

Question 10

Their risk of _____________ and the need for active treatment of ______________ should form part of the ongoing management of coeliac disease.

Answer 10

osteoporosis

bone disease

Question 11

Patients who have coeliac disease are at an increased risk of malabsorption of key nutrients such as _____________ and ____________

Answer 11

calcium

vitamin D

Question 12

Confirmed cases of refractory coeliac disease should be referred to a specialist centre. Treatment with _______________ can be considered for initial management while awaiting specialist advice

Answer 12

prednisolone

Question 13

Patients with coeliac disease often have a degree of ___________________

Answer 13

functional hyposplenism; for this reason, all patients with celiac disease are offered the pneumococcal vaccine

Question 14

Coeliac UK recommends that everyone with coeliac disease is vaccinated against _____________ infection and has a booster every _______ years

Answer 14

pneumococcal

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