CD4 subsets

Question 1

Help macrophages respond to intracellular bacterial and viral infections

Answer 1

TH1

Question 2

Help basophils, mast cells, eosinophils, and B cells respond to parasitic infection

Answer 2

TH2

Question 3

Help B cells become antibody producing plasma cells

Answer 3

TFH

Question 4

Help recruit neutrophils to infected tissues, specifically mucosal tissues

Answer 4

TH17

Question 5

Cytokines that induce Th1 differentiation

Answer 5

IL-12 and IFN-g

Question 6

Defining transcription factor for Th1

Answer 6

T-bet

Question 7

Characteristic cytokines produced by Th1

Answer 7

IFN-g

Question 8

Cytokines that induce Th17 differentiation

Answer 8

IL-6 and TGF-B

Question 9

Defining transcription factor for Th17

Answer 9

ROR-gT

Question 10

Characteristic cytokines produced by Th17

Answer 10

IL-17 and IL-6

Question 11

Cytokine that induces Th2 differentiation

Answer 11

IL-4

Question 12

Defining transcription factor for Th2

Answer 12

GATA3

Question 13

Characteristic cytokines produced by Th2

Answer 13

IL-4 and IL-5

Question 14

Cytokine that induces TFH differentiation

Answer 14

IL-6

Question 15

Defining transcription factor for TFH

Answer 15

Bcl6

Question 16

Characteristic cytokine produced by TFH

Answer 16

IL-21

Question 17

Cytokine that induces Treg differentiation

Answer 17

TGF-B

Question 18

Defining transcription factor for Treg

Answer 18

FoxP3

Question 19

Signature cytokines for Treg

Answer 19

TGFB and IL-10

Question 20

Keep effector T cells in check and prevent autoimmunity

Answer 20

Treg