CD4 and CD8 T cell activation Flashcards
1
Q
what cytokines do Th1 cells make
A
- IFN-y
- IL-2
2
Q
what cytokines do Th2 cells make
A
- IL-4
- IL-5
3
Q
IFN-y
A
- activates macrophages
- increases class II
- costiumulator expression
- enhances IgG2a
4
Q
IL-4
A
- T and B cell growth factor
- enhances IgE and IgG1
- suppresses macrophage activation
- produced by T cells, mast cells
- acts on T cells, B cells, macrophages
5
Q
Th1 cells
A
phagocyte mediated elimination of pathogens
6
Q
Th2 cells
A
mediators of allergy, protection against helminths
7
Q
T follicular helper cells (Tfh)
A
help B cells become activated, switch isotype, and increase antibody affinity
8
Q
Th17
A
enhance the neurophil response to funal and extracellular bacterial infections
9
Q
Treg
A
suppress the activities of other effector T cell populations
10
Q
CD8 T cells
A
kill virus-infected cells
