CD Markers Flashcards
CD2
T cells, thymocytes, NK cells
Adhesion
CD3
T cells, thymocytes
Signal transduction by TCR
CD4
TH cells, thymocytes, monocytes, and macrophages
Co-receptor for TCR-MHC-II
Receptor for HIV
CD8
CTLs, some thymocytes
Coreceptor for MHC I
CD14 (LPS receptor)
Monocytes, Macrophages, Granulocytes
Binds LPS
CD 16 (Fc receptor-bind antibodies attached to infected body cells)
NK cells, macrophages, neutrophils Opsononization ADCC (Antibody-dependent cell-mediated toxicity) -->NK
CD18
Leukocytes-like neutrophils, Cell adhesion molecule for attaching to endothelium, (absent in Leukocyte Adhesion Deficiency)
CD19
B cells
Coreceptor w/ CD 21 for B cell activation
CD20
Most or all B cells
B cell activation
CD21 (CR2, C3d receptor)
Mature B cells
Receptor for complement fragment C3d, forms coreceptor CD19,
Receptor for Epstein-Barr Virus
CD25
Activated TH cells and Treg
Alpha chain of Il-2 receptor
CD28
T cells
T cell receptor for costimulatory molecule B7
CD34
Precursors of hematopoeitic cells, endotheliall cells in HEV
Cell-cell adhesion, binds L-selectin
CD40
Antigen Presenting Cells: B cells, macrophages, dendritic cells, endothelial cells
Binds CD40L, T cell dependent B cell, macrophage, dendritic cell and endothelial cell activation
CD56
NK cells
Unknown Function