CD Markers

Question 1

Uncommitted Hematopoietic Progenitor Cells

Answer 1

CD34+

Question 2

Earliest antigen to appear in myeloid differentiation

Answer 2

CD33-> CD13, CD14, and CD 117

Question 3

CD marker of erythroid maturation

Answer 3

CD71 (loss of CD33)

Question 4

2 markers of Megakaryocytic differentiation

Answer 4

CD41 (gp IIb) and CD61 (GP IIb/IIIa)

Question 5

NK Cell differentiation

Answer 5

CD56 and CD 57

Question 6

Monocyte differentiation (4)

Answer 6

CD11, CD 14, CD 15, and CD 64

Question 7

B and T cell lymphocytes (2)

Answer 7

HLA-DR and TdT

Question 8

B Cell Maturation Markers (3)

Answer 8

CD10, CD19, and CD20

Question 9

T cell markers (4)

Answer 9

CD3, CD4, CD7, and CD8

Question 10

CLL phenotype (3 pos)

Answer 10

CD20 +, CD5+, CD23 +

Question 11

Mantle Cell Phenotype

Translocation:

Answer 11

CD20+, CD5+, CD23-

t11;14, cyclin D1

Question 12

Marginal Zone Lymphoma Phenotype (2pos, 1neg)

Answer 12

CD20+, CD5-, CD43+

Question 13

cHL immunophenotype (2pos, 2neg)

Answer 13

CD15+, CD30+, CD20-, CD45-

Question 14

FL immunophenotype (1pos, 2neg)
translocation

Answer 14

CD10+, CD5-, CD23-

t(14; 18)-> BCL2

Question 15

Hairy Cell Leukemia Immunophenotype (3pos)

Answer 15

CD20+, CD25+, CD 103+

Question 16

LPL immunophenotype (3 pos)

Answer 16

CD20+, CD38+, CD138 + with light chain restricted plasma cells

Question 17

MM immunophenotype

Answer 17

CD20-, CD 56+, CD 38+, CD138 +

Question 18

How do you tell between B cell and T Cell ALL

Answer 18

T cell will be CD3+

Question 19

Difference between PTCL and AITL

Answer 19

PTCL is CD30+, AITL is CD30-

Question 20

Better prognosis, ALK pos or ALK neg Anaplastic large cell lymphoma?

Answer 20

ALK positive