CC QUIZ 3 Flashcards
Glucagon is release during stress and fasting state, which among the ff. is not an action of glucagon?
a. Formation of Glucose-6-phosphate from noncarbohydrate sources
b. Decomposition of fat
c. breakdown of glycogen to glucose 6 PO4
d. glucose metabolism to pyruvate
Glucose metabolism to pyruvate
NOTE:
is glycolysis which is an action of insulin
Which among the ff. is true
a. Type 1 DM occurs exclusively among children
b. Type 1 DM: Undetectable C peptide and absent insulin secretion
c. Type 2 DM: Associated with obesity and sedentary lifestyle
d. Type 2 DM: consistent to have a life threatening DKa
Type 2 DM: Associated with obesity and sedentary lifestyle
NOTE:
A – it also occur in some adult
B- insulin is absolute deficient
D – Dka occurs commonly in type 1
Sodium fluoride is ideal for glucose analysis because:
a. It inhibits glycolysis
b. It preserves glucose up to 3 days
c. It is bacteriostatic
d. AOTA
AOTA
In glucose oxidase method, what is the reagent enzyme to cause color reaction?
a. Glucose oxidase
b. Hexokinase
c. Peroxidase
d. G6PD
Peroxidase
A diabetic patient results are as follow:
i. FBS: 140 mg/dL - NV: <126 mg/dL
ii. RBS: 220 mg/dL -NV: <200mg/dL
iii. Repeated HbA1c : 3% -NV: 4-6%
Note: the patient has Low RBC count and increase reticulocyte count.
The results shown indicate?
a. Test is invalid, FBS and RBS are in conflict with HbA1c result
b. Patient has low glucose due to low HbA1c
c. Rerun HbA1c test
d. HbA1c is invalid due to the CBC result of the patient
HbA1c is invalid due to the CBC result of the patient
NOTE:
The patient has hemolytic anemia (low RBC count and high reticulocyte count). Therefore, HbA1c will be falsely low.
Proceed to fructosamine test
In 3hr-OGTT test, the first blood collection is done
a. Before the ingestion of glucose load
b. Right after the ingestion of glucose load
c. 1 hr after the ingestion of glucose load
d. 1 hr before the ingestion of glucose load
Before the ingestion of glucose load
NOTE:
fasting plasma glucose
1-hour plasma glucose
2-hour plasma glucose
or a 3-hour plasma glucose
If the blood glucose of a patient is 90 mg/dL, what is his estimated normal CSF glucose?
a. 54 mg/dL
b. 78 mg/dL
c. 110 mg/dL
d. 80 mg/dL
54 mg/dL
Common symptoms of Glycogen storage diseases?
a. Cardiomyopathy and macroglossia
b. Renomegaly and Rickets
c. Hypoglycemia and Hepatomegaly
d. Liver cirrhosis and esophageal varices
Hypoglycemia and Hepatomegaly
NOTE:
A – pompe
B – Fanconi bickel
D – Anderson
Which among the ff. is not Type B lactic acidosis?
a. Diabetes mellitus
b. Salicylate ingestion
c. Ethanol intoxication
d. CHF
CHF
Lipids found in the cell membrane?
a. Phospholipid and TAG
b. Phospholipid and Cholesterol
c. Phospholipid and Lipoproteins
d. Phospholipid only
Phospholipid and Cholesterol
Deficiency of lipoprotein lipase will lead to
a. Failure of cholesterol esterification
b. Poor Hydrolysis of TAG to be transferred to adipose tissue
c. Emulsification of fats in the gut
d. Inability to maintain the lipoprotein structure
Poor Hydrolysis of TAG to be transferred to adipose tissue
NOTE:
C – bile does the emulsification of fats in the gut
D – apolipoprotein maintains the lipoprotein structure
Acute and recurrent pancreatitis occurs because
a. TAG-rich-chylomicrons are deposited in the capillaries of pancreas
b. TAG-rich-Chylomicrons occlude the pancreatic blood vessel
c. LDL causes plaque in the pancreas
d. AOTA
TAG-rich-Chylomicrons occlude the pancreatic blood vessel
GC-MS is the latest reference method for
a. TAG
b. Cholesterol
c. A and B
d. NOTA
A and B
Decreased TAG
i.Hyperthyroidism
ii.Malabsorption
iii.Brain infarction
iv.Nephrotic syndrome
a. AOTA
b. i,iii,iv
c. i,ii,iii
d. i,ii
i,ii,iii
The major interference in TAG determination?
a. Bilirubin
b. Vit C
c. Hemolysis
d. Glycerol
Glycerol
Essential fatty acid that is/are inflammatory regulator?
a. Linoleic (omega 3)
b. Linolenic acid (omega 6)
c. Both a and b
d. Elaidic acid
Both a and b
True about cholesterol
a. Majority of the cholesterol comes from our diet
b. It is used for the production of progesterone, estrogen, and testosterone
c. For cell membrane pliancy/elasticity
d. Loss of cholesterol leads to spherocytosis
It is used for the production of progesterone, estrogen, and testosterone
NOTE:
A – majority comes from the liver
C – for cell membrane tensile, pliancy is phospholipid
D – target cell and acanthocytosis
Known interference in cholesterol determination?
a. Ascorbic acid
b. Bilirubin
c. Hemoglobin
d. AOTA
AOTA
True about lipoproteins
a. The size of lipoprotein is directly proportional to its lipid content
b. Lipid content is inversely proportional to density
c. Density is inversely proportional to the size of the lipoprotein
d. AOTA
AOTA
Every decade from the age of 20 and above, cholesterol increases by
a. 5 mg/dL
b. 20 mg/dL
c. 30 mg/dL
d. 10 mg/dL
20 mg/dL
Which apolipoprotein is associated to alzheimer’s disease
a. Apo E2
b. Apo E4
c. Apo B-100
d. Apo B-48
Apo E4
In lipoprotein electrophoresis, a spike in beta region means
a. An increase in HDL
b. An increase in LDL
c. Normal
d. An increase in VLDL
An increase in LDL
NOTE:
Alpha 1 region – HDL
Pre beta region – VLDL
Beta region – LDL
Origin – Chylomicron
In ultracentrifugation, what is the ascending order of lipoprotein, in terms of their densities?
a. HDL, LDL, IDL, VLDL, Chylomicron
b. Chylomicron, VLDL, IDL, LDL, HDL
c. HDL, VLDL, IDL, LDL, Chylomicron
d. Chylomicron, LDL, IDL, VLDL, HDL
Chylomicron, VLDL, IDL, LDL, HDL
the most common medium for separation of intact lipoproteins for it provides a CLEAR BACKGROUND AND CONVENIENCE IN USE.
a. Polyacrylamide gel
b. Agarose
c. Cellulose acetate
d. NOTA
Agarose
NOTE:
polyacrylamide gel is used for separation of lipoprotein classes,subclasses, and the apolipoproteins
In lipoprotein immunoassay, the reagent antibody in solid phase is specific to
a. Lipoprotein
b. Lipids
c. Apolipoprotein
d. AOTA
Apolipoprotein
Fasting becomes a requirement if this lipid is present in the test request?
a. Cholesterol
b. LDL
c. TAG
d. B and C
TAG
NOTE:
* When TAG and LDL C are being measured, fasting becomes a requirement,
BUT LDL is NOT A LIPID but a protein
Increase of this/these is CARDIOPROTECTIVE?
a. HDL
b. Apo A1
c. A and B
d. LDL
A and B
Order of lipoprotein size/diameter from largest to smallest?
a. Chylomicron, VLDL, LDL, HDL
b. Chylomicron, LDL, VLDL, HDL
c. HDL, LDL, VLDL, Chylomicron
d. Chylomicron, VLDL, HDL, LDL
Chylomicron, VLDL, LDL, HDL
According to the following results, what condition would probably be suspected?
hypoalbuminemia
Microalbuminuria positive
Oval fat bodies positive
A2 macroglobulin increase
Increase serum TAG and Cholesterol
Increase BUN and Creatinine
a. Hypercholesterolemia
b. Diabetes mellitus
c. Nephrotic syndrome
d. SLE
Nephrotic syndrome
End color reaction of Liebermann Burchardt?
a. Blue
b. Red
c. Orange
d. Green
Green
