CC (MJ) Part 2 Flashcards

1
Q

Conversion factor for Bilirubin

A

17.1

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2
Q

Conversion factor for Albumin

A

10

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3
Q

Conversion factor for Na/K

A

1

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4
Q

Conversion factor for TAG

A

0.0113

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5
Q

Conversion factor for Uric acid

A

0.0595

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6
Q

Conversion factor for Glucose

A

0.0555

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7
Q

Conversion factor for T4 (Thyroxine

A

12.9

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8
Q

Conversion factor for Total protein

A

10

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9
Q

Conversion factor for Cholesterol.

A

0.026

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10
Q

Conversion factor for BUN

A

0.357

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11
Q

SI units for glucose>

A

mmol.L

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12
Q

SI units for Creatinine

A

umol/L

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13
Q

SI units for chlorise

A

mmol/L

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14
Q

SI units for Bilirubin

A

umol/L

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15
Q

SI units for CO2 and O2?

A

kPa

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16
Q

Panic Value for glucose?

A

<40 and >500mg/dL

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17
Q

Panic value for bilirubin?

A

> 18 mg/dL

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18
Q

Formula for carbonic acid?

a. (Na + K) - (Cl + HCO3)
b. pCO2 x 0.031
c. pKa + log (HCO3 / H2CO3)
d. Total T4 x THBR

A

b

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19
Q

Formula for Free T4 index

a. (Na + K) - (Cl + HCO3)
b. pCO2 x 0.031
c. pKa + log (HCO3 / H2CO3)
d. Total T4 x THBR

A

d

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20
Q

Formula for Coeafficient of Variation?

A

(Mean/SD) x 100

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21
Q

g of NaCl with 100 mL of water to make NSS>

A

85g/ 100mL

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22
Q

Standard clinical specimen for Carbohydrates is?

a. Venous plasma
b. Serum
c. Arterial plasma

A

a

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23
Q

Venous blood has __________ glucose compared to arterial

A

lower

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24
Q

Whole blood gives approximately ______________ glucose levels than serum plasma

a. 10-15% Higher
b. 10-15% Lower
c. 5-10% Higher
d. 5-10% Lower

A

b

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25
Q

At ROOM temp, glucose decrase at a rate of

a. 7 mg/dL/hr
b. 2 mg/dL/hr
c. 3 mg/dL/hr
d. 8 mg/dL/hr

A

a

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26
Q

4 C glucose decrease at the rate of:

a. 7 mg/dL/hr
b. 2 mg/dL/hr
c. 3 mg/dL/hr
d. 8 mg/dL/hr

A

b

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27
Q

___ mg of sodium fluoride can prevent glycolysis for 48-72 hrs

A

2

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28
Q

6-10 mg where NaF is used alone, ___ to ____ time greater concentration that usual is required

A

3 - 5

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29
Q

Fluoride binds to magnesium which causes inhibition of the enzyme ?

a. Insulin
b. Glucagon
c. Enolase
d. Lyases

A

c

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30
Q

CSF glucose conc. is approx. _________ that of plasma concentration

a. 20-40%
b.<1%
c. 60-70%
d. <10%

A

c

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31
Q

CSF protein has _____ than of plasma protein

a. 20-40%
b.<1%
c. 60-70%
d. <10%

A

b

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32
Q

Blood glucose should be obtained _____ hrs before the spinal tap

A

1-2 hours

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33
Q

10% contamination of 5% dextrose will _________________

a. Increase glucose by 500mg/dL or more
b. Decrease glucose by 500mg/dL or more
c. Increase glucose by 100mg/dL or more
d. Decrease glucose by 100mg/dL or more

A

a

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34
Q

In OGTT:

Blood glucose should return to normal after:

a. 2 hours
b. 3 hours
c. 1 hour
d. 4 hours

A

a

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35
Q

Patient is asked to consume a ___________ carbohydrate intake at least _________ carbs per day for __ days prior to the test

a. Normal to high, 150g, 3 days
b. Normal to low, 150g, 3 days
c. Normal to high 100g, 3 days
d. Normal to high 150g, a day

A

a

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36
Q

Patient should fast atleast?

A

8-10 hrs

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37
Q

OFT test should perfomed in thE?

A

Morning

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38
Q

Glucose load for adult?

A

75g

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39
Q

Patient should finish drinking glucose load within ?

A

5minuetes

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40
Q

If patient vomits, discontinue the test

T or F

A

T

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41
Q

1% change is HbA1c is equivalent to

a. 40 mg/dL
b. 30 mg/dL
c. 45 mg/dL
d. 35 mg/dL

A

d

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42
Q

Method that is not affected by other hemoglobins and temperature?

a. HPLC
b. Affinity chromatography
c. Latex chromatography
d. Laurel electrophoresis

A

b

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43
Q

Woman who had gestation diabetes are most likely to develop diabetes after?

A

5-10 years

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44
Q

Renal threshold for glucose?

A

160-180 mg/dL

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45
Q

Monitors insulin shock

a. Fasting blood sugat
b. OGTT
c. Random blood sugar
d. HbA1c

A

c

46
Q

Whipple’s triad is associated with?

a. Insulinoma
b. Hypoglycemia
c. Hyperglycemia
d. a and b
e. a and c

A

d

47
Q

Most common glycogen storage disorder, which is deficient in G6P

a. Von Gierke disease
b. Crigler Najjar
c. Gilbert syndrome
d. Dubin Johnson syndrome

A

a

48
Q

Ortho toluidine method is also known as?

A

Condensation method which can produce Bluish green

49
Q

Arsenophosphomolybdate = Nelson somogyi
Phophomolybdate = Folin Wu

T or F

A

T

50
Q

Positive for condensation?

A

BLuish green

51
Q

In condensation, absorbance for bluish green?

a. 600-610 nm
b. 610-620 nm
c. 620-630 nm
d. 630-640 nm

A

c

52
Q

Reference method for glucose?

A

Hexokinase-G6PD

53
Q

Method affected by reducing and oxidizing agents?

a. GLucose oxidase
b. Hexokinase
c. Folin Wu
d. Nelsson Somogyi

A

b

54
Q

Glucose oxidase detects?

a. Alpha glucose
b. Beta glucose
c. Gamma glucose
d. Delta glucose

A

b (65%)

in a (35%)

55
Q

45%-50% Cholesterol Ester is on what lipoproteins?

A

LDL

56
Q

Unit of sedimentation rate in Ultracentrifugation?

A

Svedberg unit

57
Q

Atherosclerotic plugs are composed of?

a. Triglycerides
b. Cholesterols
c. Proteins
d. Amino acids

A

b

58
Q

NCEP Guidelines for acceptable measurment error for Coefficient of Variation

<3%

a. Triglyceride
b. LDL
c. HDL
d. TC

A

d

59
Q

NCEP Guidelines for acceptable measurment error for Coefficient of Variation

4%

a. Triglyceride
b. LDL
c. HDL
d. TC

A

b and c

60
Q

NCEP Guidelines for acceptable measurment error for Coefficient of Variation

5%

a. Triglyceride
b. LDL
c. HDL
d. TC

A

a

61
Q

Positive risk for CHD in Females?

A

55 yo

62
Q

Positive risk for CHD in males?

A

45 y

63
Q

What are the TC values?

A

Desirable: < 200
Borderline high: 200-239
High: > or equal to 240

64
Q

What are the LDL- Cholesterol Ref values?

Optimal
Near optimal
Borderline high
High
Very high

A

<100

100-129

130-159

160- 189

> 190

65
Q

What are the HDL cholesterl Ref values?

PRotective against heart disease

Major risk factor for heart disease

A

> or equal to 60

<40

66
Q

Triglycerides Ref values?

Normal

Borderline high

high

Very high

A

<150

150 - 199

200-499

> or equal to 500

67
Q

Forms of cholesterol that reacts with cholesterol oxidase?

A

Free Cholesterol

68
Q

First enzyme used in the enzymativ method of cholesterol?

a. Cholesterol esterase
b. Lipase
c. LDH
d. Peroxidase

A

a

69
Q

Lipid stains used in lipoprotein electrophoresis

A

SOFteR

Sudan black B
Oil Red O
Fat Red 7B

70
Q

Lieberman-Buchard

a. One step (Colorimetry)
b. 2 Step (Extraction and Colorimetery)
c. 3 Step (Extraction, Saponification, C)
d. 4 Step

A

a

71
Q

Abell

a. One step (Colorimetry)
b. 2 Step (Extraction and Colorimetery)
c. 3 Step (Extraction, Saponification, C)
d. 4 Step

A

c

72
Q

Bloors (Carr and Drekter)

a. One step (Colorimetry)
b. 2 Step (Extraction and Colorimetery)
c. 3 Step (Extraction, Saponification, C)
d. 4 Step

A

b

73
Q

Schoenheimer / Sperry

a. One step (Colorimetry)
b. 2 Step (Extraction and Colorimetery)
c. 3 Step (Extraction, Saponification, C)
d. 4 Step

A

d

74
Q

Protein Electerophoresis:

Ceruplasmin

a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma

A

b

75
Q

Protein Electerophoresis:

Haptoglobin

a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma

A

b

76
Q

Protein Electerophoresis:

Transferrin (Siderophilin)

a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma

A

c

77
Q

Protein Electerophoresis:

Complement

a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma

A

c

78
Q

Protein Electerophoresis:

C-Reative protein

a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma

A

c

79
Q

Protein Electerophoresis:

IG

a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma

A

d

80
Q

Indicator of malnutrition

A

Prealbumin (Transthyretin)

81
Q

Associated with increased in albumin

a. Dehydration
b. Excersice
c. Walking

A

a

82
Q

Decreased in Ceruplasmin is associated with what disease?

A

Wilson’s disease

83
Q

Which of the following APR are decrease during inflammation?

a. Prealbumin
b. Albumin
c. Transferrin
d. All of the above

A

d

84
Q

The following are NOT APR Except:

a. Alpha fetoprotein
b. Gc globulin
c. Inter alpha trypsin inhibitor
d. Ceruplasmin

A

d

85
Q

The following are NOT APR Except:

a. Thyroxin binding globulin
b. Lipopoteins (HDL)
c. Beta2 - microglobulins
d. all of the above

A

b

86
Q

Beta Gamma bidging

a. Cirrhosis
b. MM
c. Nephrotic syndrome
d. Acute inflammation
e. Emphysema

A

a

87
Q

Increased in alpha2

a. Cirrhosis
b. MM
c. Nephrotic syndrome
d. Acute inflammation
e. Emphysema

A

c

88
Q

Monovlonal spike in gamma region

a. Cirrhosis
b. MM
c. Nephrotic syndrome
d. Acute inflammation
e. Emphysema

A

b

89
Q

Increased in alpha 1 and 2

a. Cirrhosis
b. MM
c. Nephrotic syndrome
d. Acute inflammation
e. Emphysema

A

d

90
Q

Measures the AMOUNT of Peptide bonds

a. Biuret mthod
b. Khedahl method
c. Jaffe

A

a

91
Q

Rgt of Biuret method?

A

RANK

Rochelle salt

Alkaline copper sulfate

Sodium hydroxide (NaOH)

Potassium Iodid

92
Q

Measures the Nitrogen contents of Proteins

a. Biuret mthod
b. Khedahl method
c. Jaffe

A

b

93
Q

Average nitrogen content of protein?

a. 10%
b. 2.14%
c. 16%
d. 12%

A

c

94
Q

Factor used to convert nitrogen content to protein concentration

a. 5.64
b. 6.54
c. 4.65
d. 6.45

A

b

95
Q

Most commonly used dye binding technique in proteins?

a. Bromcresol Green
b. Bromcresol purple
c. Ninhydrin
d. Neutral red

A

a

96
Q

Most specific and sensitive used dye-binding technique for albumin

a. Bromcresol Green
b. Bromcresol purple
c. Ninhydrin
d. Neutral red

A

b

97
Q

Dye used for amino acids

a. Bromcresol Green
b. Bromcresol purple
c. Ninhydrin
d. Neutral red

A

c

98
Q

Turbidimetric methods for proteins

a. Sulfosalicylic acid
b. Trichloroacetic acid
c. Both
d. None of the above

A

c

99
Q

Total Protein - Albumin =?

A

Globulin

100
Q

Icterus index involves dilutingserum with saline until it visually matches the color of?

a. 0.01% potassium dichromate
b. 0.01% potassium monochromate
c. 0.01% Sodium dichromate
d.0.01% Sodium monochromate

A

a

101
Q

Bilirubin value taken

Before the addition of dissociating/accelerator reagent

a. B2
b. B1
c. Total Bilirubin

A

a

102
Q

Bilirubin value taken

After the addition of dissociating/accelerator reagent

a. B2
b. B1
c. Total Bilirubin

A

c

103
Q

Bilirubin covalently bound to protein which contributes to direct bilirubin values

A

Delta bilirubin

104
Q

Assess the patency of the bile duct

A

Bilirubin

105
Q

Deficiency of UDPGT

a. Von Gierke disease
b. Crigler Najjar
c. Gilbert syndrome
d. Dubin Johnson syndrome

A

b

106
Q

Defective hepatic excretion of bilirubin

a. Von Gierke disease
b. Crigler Najjar
c. Gilbert syndrome
d. Dubin Johnson syndrome

A

d

107
Q

Defective hepatic uptake of bilirubin

a. Von Gierke disease
b. Crigler Najjar
c. Gilbert syndrome
d. Dubin Johnson syndrome

A

c

108
Q

Albumin, proteins, Coag proteins

a. Synthetic function
b. Metabolic function
c. Detoxification
d. Excretory function

A

a

109
Q

Bilirubin

a. Synthetic function
b. Metabolic function
c. Detoxification
d. Excretory function

A

c

110
Q

Ammonia and drugs

a. Synthetic function
b. Metabolic function
c. Detoxification
d. Excretory function

A

c

111
Q

Acetyl Coa (From glucose), amino acid conversion, fatty acid metabolism

a. Synthetic function
b. Metabolic function
c. Detoxification
d. Excretory function

A

b

112
Q

Bile acids

a. Synthetic function
b. Metabolic function
c. Detoxification
d. Excretory function

A

d