CC (MJ) Part 2 Flashcards
Conversion factor for Bilirubin
17.1
Conversion factor for Albumin
10
Conversion factor for Na/K
1
Conversion factor for TAG
0.0113
Conversion factor for Uric acid
0.0595
Conversion factor for Glucose
0.0555
Conversion factor for T4 (Thyroxine
12.9
Conversion factor for Total protein
10
Conversion factor for Cholesterol.
0.026
Conversion factor for BUN
0.357
SI units for glucose>
mmol.L
SI units for Creatinine
umol/L
SI units for chlorise
mmol/L
SI units for Bilirubin
umol/L
SI units for CO2 and O2?
kPa
Panic Value for glucose?
<40 and >500mg/dL
Panic value for bilirubin?
> 18 mg/dL
Formula for carbonic acid?
a. (Na + K) - (Cl + HCO3)
b. pCO2 x 0.031
c. pKa + log (HCO3 / H2CO3)
d. Total T4 x THBR
b
Formula for Free T4 index
a. (Na + K) - (Cl + HCO3)
b. pCO2 x 0.031
c. pKa + log (HCO3 / H2CO3)
d. Total T4 x THBR
d
Formula for Coeafficient of Variation?
(Mean/SD) x 100
g of NaCl with 100 mL of water to make NSS>
85g/ 100mL
Standard clinical specimen for Carbohydrates is?
a. Venous plasma
b. Serum
c. Arterial plasma
a
Venous blood has __________ glucose compared to arterial
lower
Whole blood gives approximately ______________ glucose levels than serum plasma
a. 10-15% Higher
b. 10-15% Lower
c. 5-10% Higher
d. 5-10% Lower
b
At ROOM temp, glucose decrase at a rate of
a. 7 mg/dL/hr
b. 2 mg/dL/hr
c. 3 mg/dL/hr
d. 8 mg/dL/hr
a
4 C glucose decrease at the rate of:
a. 7 mg/dL/hr
b. 2 mg/dL/hr
c. 3 mg/dL/hr
d. 8 mg/dL/hr
b
___ mg of sodium fluoride can prevent glycolysis for 48-72 hrs
2
6-10 mg where NaF is used alone, ___ to ____ time greater concentration that usual is required
3 - 5
Fluoride binds to magnesium which causes inhibition of the enzyme ?
a. Insulin
b. Glucagon
c. Enolase
d. Lyases
c
CSF glucose conc. is approx. _________ that of plasma concentration
a. 20-40%
b.<1%
c. 60-70%
d. <10%
c
CSF protein has _____ than of plasma protein
a. 20-40%
b.<1%
c. 60-70%
d. <10%
b
Blood glucose should be obtained _____ hrs before the spinal tap
1-2 hours
10% contamination of 5% dextrose will _________________
a. Increase glucose by 500mg/dL or more
b. Decrease glucose by 500mg/dL or more
c. Increase glucose by 100mg/dL or more
d. Decrease glucose by 100mg/dL or more
a
In OGTT:
Blood glucose should return to normal after:
a. 2 hours
b. 3 hours
c. 1 hour
d. 4 hours
a
Patient is asked to consume a ___________ carbohydrate intake at least _________ carbs per day for __ days prior to the test
a. Normal to high, 150g, 3 days
b. Normal to low, 150g, 3 days
c. Normal to high 100g, 3 days
d. Normal to high 150g, a day
a
Patient should fast atleast?
8-10 hrs
OFT test should perfomed in thE?
Morning
Glucose load for adult?
75g
Patient should finish drinking glucose load within ?
5minuetes
If patient vomits, discontinue the test
T or F
T
1% change is HbA1c is equivalent to
a. 40 mg/dL
b. 30 mg/dL
c. 45 mg/dL
d. 35 mg/dL
d
Method that is not affected by other hemoglobins and temperature?
a. HPLC
b. Affinity chromatography
c. Latex chromatography
d. Laurel electrophoresis
b
Woman who had gestation diabetes are most likely to develop diabetes after?
5-10 years
Renal threshold for glucose?
160-180 mg/dL
Monitors insulin shock
a. Fasting blood sugat
b. OGTT
c. Random blood sugar
d. HbA1c
c
Whipple’s triad is associated with?
a. Insulinoma
b. Hypoglycemia
c. Hyperglycemia
d. a and b
e. a and c
d
Most common glycogen storage disorder, which is deficient in G6P
a. Von Gierke disease
b. Crigler Najjar
c. Gilbert syndrome
d. Dubin Johnson syndrome
a
Ortho toluidine method is also known as?
Condensation method which can produce Bluish green
Arsenophosphomolybdate = Nelson somogyi
Phophomolybdate = Folin Wu
T or F
T
Positive for condensation?
BLuish green
In condensation, absorbance for bluish green?
a. 600-610 nm
b. 610-620 nm
c. 620-630 nm
d. 630-640 nm
c
Reference method for glucose?
Hexokinase-G6PD
Method affected by reducing and oxidizing agents?
a. GLucose oxidase
b. Hexokinase
c. Folin Wu
d. Nelsson Somogyi
b
Glucose oxidase detects?
a. Alpha glucose
b. Beta glucose
c. Gamma glucose
d. Delta glucose
b (65%)
in a (35%)
45%-50% Cholesterol Ester is on what lipoproteins?
LDL
Unit of sedimentation rate in Ultracentrifugation?
Svedberg unit
Atherosclerotic plugs are composed of?
a. Triglycerides
b. Cholesterols
c. Proteins
d. Amino acids
b
NCEP Guidelines for acceptable measurment error for Coefficient of Variation
<3%
a. Triglyceride
b. LDL
c. HDL
d. TC
d
NCEP Guidelines for acceptable measurment error for Coefficient of Variation
4%
a. Triglyceride
b. LDL
c. HDL
d. TC
b and c
NCEP Guidelines for acceptable measurment error for Coefficient of Variation
5%
a. Triglyceride
b. LDL
c. HDL
d. TC
a
Positive risk for CHD in Females?
55 yo
Positive risk for CHD in males?
45 y
What are the TC values?
Desirable: < 200
Borderline high: 200-239
High: > or equal to 240
What are the LDL- Cholesterol Ref values?
Optimal
Near optimal
Borderline high
High
Very high
<100
100-129
130-159
160- 189
> 190
What are the HDL cholesterl Ref values?
PRotective against heart disease
Major risk factor for heart disease
> or equal to 60
<40
Triglycerides Ref values?
Normal
Borderline high
high
Very high
<150
150 - 199
200-499
> or equal to 500
Forms of cholesterol that reacts with cholesterol oxidase?
Free Cholesterol
First enzyme used in the enzymativ method of cholesterol?
a. Cholesterol esterase
b. Lipase
c. LDH
d. Peroxidase
a
Lipid stains used in lipoprotein electrophoresis
SOFteR
Sudan black B
Oil Red O
Fat Red 7B
Lieberman-Buchard
a. One step (Colorimetry)
b. 2 Step (Extraction and Colorimetery)
c. 3 Step (Extraction, Saponification, C)
d. 4 Step
a
Abell
a. One step (Colorimetry)
b. 2 Step (Extraction and Colorimetery)
c. 3 Step (Extraction, Saponification, C)
d. 4 Step
c
Bloors (Carr and Drekter)
a. One step (Colorimetry)
b. 2 Step (Extraction and Colorimetery)
c. 3 Step (Extraction, Saponification, C)
d. 4 Step
b
Schoenheimer / Sperry
a. One step (Colorimetry)
b. 2 Step (Extraction and Colorimetery)
c. 3 Step (Extraction, Saponification, C)
d. 4 Step
d
Protein Electerophoresis:
Ceruplasmin
a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma
b
Protein Electerophoresis:
Haptoglobin
a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma
b
Protein Electerophoresis:
Transferrin (Siderophilin)
a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma
c
Protein Electerophoresis:
Complement
a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma
c
Protein Electerophoresis:
C-Reative protein
a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma
c
Protein Electerophoresis:
IG
a. Alpha 1
b. Alpha 2
c. Beta
d. Gamma
d
Indicator of malnutrition
Prealbumin (Transthyretin)
Associated with increased in albumin
a. Dehydration
b. Excersice
c. Walking
a
Decreased in Ceruplasmin is associated with what disease?
Wilson’s disease
Which of the following APR are decrease during inflammation?
a. Prealbumin
b. Albumin
c. Transferrin
d. All of the above
d
The following are NOT APR Except:
a. Alpha fetoprotein
b. Gc globulin
c. Inter alpha trypsin inhibitor
d. Ceruplasmin
d
The following are NOT APR Except:
a. Thyroxin binding globulin
b. Lipopoteins (HDL)
c. Beta2 - microglobulins
d. all of the above
b
Beta Gamma bidging
a. Cirrhosis
b. MM
c. Nephrotic syndrome
d. Acute inflammation
e. Emphysema
a
Increased in alpha2
a. Cirrhosis
b. MM
c. Nephrotic syndrome
d. Acute inflammation
e. Emphysema
c
Monovlonal spike in gamma region
a. Cirrhosis
b. MM
c. Nephrotic syndrome
d. Acute inflammation
e. Emphysema
b
Increased in alpha 1 and 2
a. Cirrhosis
b. MM
c. Nephrotic syndrome
d. Acute inflammation
e. Emphysema
d
Measures the AMOUNT of Peptide bonds
a. Biuret mthod
b. Khedahl method
c. Jaffe
a
Rgt of Biuret method?
RANK
Rochelle salt
Alkaline copper sulfate
Sodium hydroxide (NaOH)
Potassium Iodid
Measures the Nitrogen contents of Proteins
a. Biuret mthod
b. Khedahl method
c. Jaffe
b
Average nitrogen content of protein?
a. 10%
b. 2.14%
c. 16%
d. 12%
c
Factor used to convert nitrogen content to protein concentration
a. 5.64
b. 6.54
c. 4.65
d. 6.45
b
Most commonly used dye binding technique in proteins?
a. Bromcresol Green
b. Bromcresol purple
c. Ninhydrin
d. Neutral red
a
Most specific and sensitive used dye-binding technique for albumin
a. Bromcresol Green
b. Bromcresol purple
c. Ninhydrin
d. Neutral red
b
Dye used for amino acids
a. Bromcresol Green
b. Bromcresol purple
c. Ninhydrin
d. Neutral red
c
Turbidimetric methods for proteins
a. Sulfosalicylic acid
b. Trichloroacetic acid
c. Both
d. None of the above
c
Total Protein - Albumin =?
Globulin
Icterus index involves dilutingserum with saline until it visually matches the color of?
a. 0.01% potassium dichromate
b. 0.01% potassium monochromate
c. 0.01% Sodium dichromate
d.0.01% Sodium monochromate
a
Bilirubin value taken
Before the addition of dissociating/accelerator reagent
a. B2
b. B1
c. Total Bilirubin
a
Bilirubin value taken
After the addition of dissociating/accelerator reagent
a. B2
b. B1
c. Total Bilirubin
c
Bilirubin covalently bound to protein which contributes to direct bilirubin values
Delta bilirubin
Assess the patency of the bile duct
Bilirubin
Deficiency of UDPGT
a. Von Gierke disease
b. Crigler Najjar
c. Gilbert syndrome
d. Dubin Johnson syndrome
b
Defective hepatic excretion of bilirubin
a. Von Gierke disease
b. Crigler Najjar
c. Gilbert syndrome
d. Dubin Johnson syndrome
d
Defective hepatic uptake of bilirubin
a. Von Gierke disease
b. Crigler Najjar
c. Gilbert syndrome
d. Dubin Johnson syndrome
c
Albumin, proteins, Coag proteins
a. Synthetic function
b. Metabolic function
c. Detoxification
d. Excretory function
a
Bilirubin
a. Synthetic function
b. Metabolic function
c. Detoxification
d. Excretory function
c
Ammonia and drugs
a. Synthetic function
b. Metabolic function
c. Detoxification
d. Excretory function
c
Acetyl Coa (From glucose), amino acid conversion, fatty acid metabolism
a. Synthetic function
b. Metabolic function
c. Detoxification
d. Excretory function
b
Bile acids
a. Synthetic function
b. Metabolic function
c. Detoxification
d. Excretory function
d
