CC Flashcards
True of cholesterol metabolism, except
A. free cholesterol is the inactive form of
cholesterol with cytotoxic property
B. Free cholesterol and phospholipids
have a hydrophilic property
C. both have hydrophilic and
hydrophobic properties
D. the process of esterification is a
“detoxification” step cholesterol ester
is almost 90% in plasma
B. Free cholesterol and phospholipids
have a hydrophilic property
It is the recommended fasting hour in
most clinical biochemistry tests: 6-8 hours
8-12 hours
True of R4s, except:
A. it is caused by random errors
B. it is observed after 2 consecutive
days
C. R means random error
D. difference between the highest and
lowest control result exceeds 4s
B. it is observed after 2 consecutive
days
It is the ideal reference limit:
2s
It is the most abundant lipid in human
plasma:
Cholesterol
True of creatinine, except:
A. a measure of the completeness of
24-hour urine collection
B. plasma creatinine may not be
increased until renal function has
deteriorated more than 50% plasma
creatinine is usually within the
reference limit in muscular diseases
C. in muscular dystrophy, plasma
creatine is decreased while urinary
creatinine is elevated
C. in muscular dystrophy, plasma
creatine is decreased while urinary
creatinine is elevated
Control values are computed based on: 1.mean
2. median
3. standard deviation
4.variance
1 and 3
if urea is the most abundant NPN in
plasma, ______________ is the least in concentration. creatine
Ammonia
Safety glasses, face shields or other eye
protectors must be worn when:
working with toxic materials
Observable symptoms of hypoglycemia can be observed when plasma glucose reach this level
plasma glucose level ≤55 mg/dL (3.0
mmol/L);
It is a subset of molecular luminescence
spectrometry and measures the amount of light intensity present over a zero
background:
Fluorometry
This method is based on the measurement f scattered light and is ideal for quantitative analysis of immunoglobulins:
Nephelometry
Serum urea levels drop in severe hepatic diseases, therefore, low BUN is not generally considered abnormal renal function
only the second is correct
True of diagnostic specificity, except
it generates more true-positive
results
Primary function of serum albumin in the peripheral blood is to
maintain colloidal osmotic
pressure
True of the ion-selective electrode, except
indirect ISE requires sample
dilution
It refers to the closeness of assayed values
Precision
It is known as the rapid serum tube
since clotting of blood would take
place within 5 minutes: pearl white
top
Orange top
This hormone which is released from the islet cells of the pancreas inhibits insulin
Glucagon
It is the reference method in the
determination of lipoproteins:
ultracentrifugation
Before an OGTT is performed, which of the following should be observed?
patient should have consumed at least 150 grams/day of carbohydrates for 3 days prior to testing
is the reference method in the
measurement of renal NPNs:
IDMS notsure
It is the only protein with enzymatic activity
transferrin
Earliest NPN to rise in plasma in cases of
kidney diseases:
Urea
Uniform turbidity in the refrigerated serum indicates elevated concentrations of lipoprotein and lipid:
pre-beta lipoprotein and
endogenous triglyceride
When serum is mixed with the alkaline
picrate reagent and the rate of change in absorbance is measured between 2 points, how do you explain this assay?
Kinetic Jaffe method
To avoid interferences caused by biotin
in immunoassays, blood should be
drawn only after how many hours of not
taking that supplement.
48 hours
The following are the diagnostic criteria
for diabetes mellitus, except:
Point-of-care assay of greater
than or equal to 140 mg/dL
It determines the components of a
sample where the x-axis represents
the mass-to-charge (m/z) ratio and the
y-axis is their relative abundance within
the sample:
mass specrometry
It is a gestational marker that is
increased in anencephaly and spina
bifida:
AFP rev
This inflammatory protein marker and APR is included in the biomarkers for COVID-19 due to its reaction to cytokine storm
CRP
In electrophoresis, A high ionic
strength prevents effective separation
of electrophoretic bands while
migration of proteins is inversely
proportional to molecular size:
both statements are correct
These are vital tests in assessing
individuals who are at risk of
developing coronary artery disease:
1. cholesterol
2. triglycerides
3. phospholipids
4. fatty acids
cholesterol and triglycerides
Which of the following is the best choice for decontaminating bench tops spilled with body fluid?
10% sodium hypochlorite
In external quality control testing, unknown samples should be processed and treated like a patient sample while the results of the proficiency testing may be shared with other diagnostic laboratories during the period of analysis:
only the first statement is correct
It is the recommended fasting hour in
most clinical biochemistry tests:
8-12 hours
It is described as the chemically
cleaned test tube that is designed for
the analysis of trace elements:
royal blue top
What is the most common cause of
trend?
deterioration of reagent
How long do we store the saved/processed serum in Chemistry?
7 days
What is the main machine/analyer used
in Chemistry?
Dimension EXL 200
Machine used for Micral test
(Microalbumin Test) and HbA1c
DCA Vantage
bad cholesterol
LDL
good cholesterol
HDL
chemical determinations may be of help in establishing the presence of seminal
fluid?
Acid phosphatase (ACP)
. A hospitalized patient is experiencing
increased neuromuscular irritability
(tetany). Which of the following tests
should be ordered immediately?
Calcium
Analysis of CSF for oligoclonal bands
is used to screen for which of the
following disease states?
Multiple sclerosis
When myocardial infarction occurs,
the first enzyme to become elevated is
CK
The preparation of a patient for
standard glucose tolerance testing
should include
High carbohydrate diet for 3 days
A critical ill patient becomes
comatose. The physician believes the
coma is due to hepatic failure. The
assay most helpful in this diagnosis is:
Ammonia
What enzyme catalyzes the
conjugation of bilirubin?
Uridine diphosphate glucoronyltranferase
What is the anticoagulant of choice
for blood gas examination?
Heparin
The nitrogenous waste product of
nucleic acid or purine metabolism is:
Uric acid
Clearance test for urea and
creatinine measure:
GFR
