Causation Flashcards

1
Q

what is a cause

A

an event, condition or characteristic without which the disease would not have occurred

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2
Q

what is the goal of causation within epidemiology

A

to identify causal relationships between disease & exposures

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3
Q

what are the guidelines to causation

A
  1. must precede the effect
  2. can be either positive the presence of an exposure or negative the absence of exposure
  3. one or multiple causal factors
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4
Q

what does causation guide veterinarian’s approach in

A

prevention
diagnosis
treatment

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5
Q

what do causal factors lead to

A

exposure and occurrence of disease

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6
Q

what are the agent factors that impact upon disease occurrence

A

infection
pathogenic
virulence

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7
Q

what is the ability of the agent to establish itself in a host

A

infection

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8
Q

what is the ability of an agent to produce disease in a host

A

pathogenic

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9
Q

what is the measure of severity of disease due to agent

A

virulence

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10
Q

true or false:
the stronger the association between a presumed causal factor and disease or outcome, the more likely a cause - effect relationship occurs

A

true

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11
Q

what is the evidence provided reflecting that your exposure or cause preceded the outcome

A

temporal precedence

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12
Q

what is occurring when the cause-effect relationship can be explained by biological mechanisms

A

biological plausibilty

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13
Q

what is specificity

A

the causal relationship is specific, meaning there is only one exposure that causes one outcome

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14
Q

what is supported by any new piece of biological evidence that’s discovered should solidify what is already known about a biological mechanism for a disease

A

coherence

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15
Q

what is a causal relationship between a cause and an outcome, already established for a similar exposure or disease

A

analogy

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16
Q

what do causal relationships need to be supported by

A

results from randomized controlled trials

17
Q

what is used to measure the strength of association between causal factor and disease

A

relative risk
odds ration

18
Q

what ratio is used in cohort studies

A

relative risk

19
Q

what ratio is used in case-control studies

A

odds ratio

20
Q

what factors impair making causal inferences

A

lengthy time interval between “cause” and “effect”
multiple “causes” leading to same “effect”
causal factors requiring other factors for “effect”

21
Q
A