Case-GIB Flashcards
What is a med class that predisposes pts to ulcers/UGIB
NSAIDS
What BUN:Cr is indicative of a GIB
> 30:1
occurs because blood is absorbed as it passes through the small bowel and patients may have decreased renal perfusion. The higher the ratio, the more likely the bleeding is from an UGI source
What would the etiology be if the Cr was >1 (if BUN >30)?
Renal
You have a pt whose BUN:Cr is 45:1? What is the etiology?
GIB
Normal AST range?
0-35IU
Normal ALT range?
0-35IU
Normal ALP range?
30-120IU
Normal total protein?
6-8g/dL
Normal total bili?
0-1mg/dL
Normal albumin?
3.5-6mg/dL
Normal Ca2+
8.5-10
When do you check for corrected Ca2+?
If albumin <3.5mg/dL
5 steps for initial GIB management in the ER
1. 2 large bore IVs (make pt NPO) 2. Type & Cross 3. 500- 1000cc Fluids (while waiting for blood) 4. Blood Transfusion (1unit PRBC) 5. find the bleed (call GI for EGD) ***stop the damn NSAIDS
What Hgb do we transfuse at w/o sx?
What Hgb do we transfuse at if pts have sx or cardiac dz?
7 or less
8
Ideal Time frame for endoscopy
< 12hrs
Classification for Grading GIBs?
Forest classification
Name the 6 Forest grades (worst to less bad)
- Active spurting vessel
- Oozing (active) vessel
- Visible vessel, not bleeding (high risk for bleed)
- Adherent Clot
- Flat-pigmented spot
- Ulcer, clean w/o blood
(risk for rebleed)
Tx options for GIB during EGD?
What can we add to the 2 Tx options?
**Clips
**Thermal coagulation (heat)
can add on Epinephrine (constriction of vessel)- NO FINGERS, NOSE, TOES, PENIS
You can D/C a GIB if 3 things are present…
No comorbids
Hgb NL
Stable VS
Every GIB should receive this med class (&dose)!
PPI
(pantoprazole/ esomeprazole)
80mg
T/F: PPI for GIB can be given PO (acutely)?
False! IV only
What are the positives of giving a PPI for a GIB (4)?
• Suppress gastric acid (increase pH of stomach)
(Up to 36hrs)
• Promote faster healing of ulcer
• Control PUD sx
• Stabilize blood clots /promotes hemostasis
(via higher pH)
T/F: H2 blockers/combo PPI & H2 blockers work just as well as a PPI alone (IV)
False. not as good
How long to continue PPI for GIB? can you do PO after bleed stopped 72hrs?
4-12 weeks
yes
Education of GIB prevention (3):
Which is an independent risk factor for PUD?
- Stop smoking
- Stop drinking >1drink/d
- Stop NSAID use (4x increase of PUD, as well as more refractory ulcers and increased rate of complications like bleeding)
- Always ask about OTC drugs!!!!!
Smoking is an individual risk factor for GIB
DDx for PUD?
Esophagitis (reflux esophagitis) Mallory Weiss Tear Esophageal Varices from portal HTN Upper GI tumor Angiodyspasia (Varicose Vein in GIT)
Etiology in this case?
How did our pt get a GIB?
What else can cause the etiology?
PUD
NSAIDS, ETOH, Smoking
-H. pylori
T/F: Bx for H.pylori is accurate if taken during an EGD?
True, but if bleeding, a (-) result cant r/o H. Pylori
Use urea breath or stool Ag to confirm (-) test
What drug can be used to reduce splanchnic blood flow & inhibit gastric acid secretion & useful if EGD not avail for 72hrs?
Octreotide (SST)
When should a pt go back on ASA after a GIB? What circumstances?
After bleeding stopped.
IF Hx of CVA, CAD
What Physical Exam is SUPER IMPORTANT for suspected GIB?
DRE
What part of Hx is super important for GIB?
Medications
=NSAIDS
What part of Objective is SUPER important for GIB?
Labs
How do we calculate who is low risk and can be managed as outpatient or discharged early after EGD for GIB?
-Glasgow Blatchford Score (GBS) or Rockall score calculate risk
Using the risk scores, we can calc who is low risk and can be dc’d early/ managed output.
Which risk score can be calculated before EGD? After EGD?
Glasgow-Blatchford Scale-Calculated before EGD results Uses: BUN Hgb SBP pulse presence of melena syncope hepatic Dz, and/or HF.
Rockall-After EGD results Based on: age presence of shock comorbidity Dx EGD results.
T/F:All patients with PUD should undergo testing for H. pylori.
True
When can you switch from IV to PO PPI in GIB from PUD?
72hrs after endoscopy (stop bleed)
Some Signs of GIB (5)
Slightly pale. Tachycardic. Mild generalized abd tender (+)hemoccult stool dizzy when standing
If a pt needs ASA therapy after a GIB, what Rx should they use as maintenance therapy to reduce risk of ulcer complications/ reoccurrence?
PPI
Omeprazole
20mg QD