Case Based Learning

Question 1

What are Shneider’s first rank symptoms of schizophrenia?

Answer 1

A - Auditory Hallucinations.
B - Broadcasting of Thought.
C - Controlled Thought (delusions of control).
D - Delusional Perception

Question 2

What are the genetic incidences of schizophrenia?

Answer 2

No relative with schizophrenia 1 in 100
1 parent 1 in 10
1 identical twin 1 in 2
1 non-identical twin 1 in 8

Question 3

What is the only known anti-psychotic to not cause any tardive dyskinesia?

Answer 3

Clozapine

Question 4

What are the side effects of clozapine?

Answer 4

Neutropenia
Seizures
Idiopathic hyperthermia
Weight gain
Salivation

Question 5

How is metabolic syndrome characterised?

Answer 5

Obesity, Hypertension, Dyslipidaemia and Abnormal Glucose Metabolism. It is 2-4 times more common in people with Serious Mental Illness

Question 6

When can metabolic syndrome be diagnosed?

Answer 6

if 3 or more of the following are present:
BP >130/85
Serum HDL Cholesterol >1.04 (male) or >1.29 (female)
Serum Triglyceride >1.69
Fasting Glucose >6.1
Waist Circumference >102cm (male) or >88cm (female)

Question 7

What are the most problematic anti-psychotics in causing obesity, diabetes and metabolic syndrome?

Answer 7

Clozapine

Olanzapine

Question 8

Which drugs are most likely to cause hyperprolactinaemia?

Answer 8

Amisulpride
Risperidone
Typical antipsychotics

Question 9

What are the features of hyperprolactinaemia?

Answer 9

Galactorrhea.
Menstrual irregularities.
Sexual dysfunction.
Osteoporosis.
Increased risk breast cancer.
Serum Prolactin levels should be checked if any pt reports such symptoms.

Question 10

What is the only psychological therapy not shown to aid in schizophrenia?

Answer 10

Individual psychodynamic therapy