Case 6 (MS) Flashcards
1
Q
What are the 3 main aspects of MS that are treatable ?
A
- anti-inflammation
- preventing relapse
- immunosuppression
2
Q
What drugs are used as anti-inflammatories in MS?
A
Corticosteroids …
- Prednisone
- Methylprednisolone
3
Q
What drugs are used to prevent relapse in MS?
A
- IFN-B
- Natalizumab
4
Q
What is the MOA of IFN-B?
A
Decrease T-cell proliferation
Decrease T-cell activation
Decrease T-cell migration
5
Q
What drugs are used as immunosuppressants in MS?
A
Terifluromide (aubagio)
6
Q
What is the MOA of terifluromide (aubagio)?
A
Inhibits DHODH = decreases T-cell function
