Case 43 - 21 yo M with sore throat

Question 1

Differential diagnosis

Answer 1

Infectious mononucleosis
Pharyngitis
Acute retroviral syndrome

Question 2

Diagnostic work-up

Answer 2

CBC with peripheral smear
Monospot test
Anti-EBV antibodies
Throat culture
HIV antibody and viral load

Question 3

Differential diagnosis

Answer 3

Infectious mononucleosis (sore throat, LUQ pain, ill contact, lymphadenopathy)
Pharyngitis (sore throat, low-grade fever, cigarette smoking, lymphadenopathy)
Acute retroviral syndrome (sore throat, two sexual partners, sexually active with men and women, h/o STDs)