Case 16 Flashcards
(47 cards)
What is shock?
A life threatening condition where there is circulatory failure (decreased blood flow). There is inadequate tissue and organ perfusion.
What is hypovolemic shock?
Shock caused by significant loss of fluids from body
Causing decreased blood flow
Eg caused by diarrhea, vomiting or bleeding
What is cardiogenic shock?
Heart failure (pump failure)
Causing decreased blood flow
What is obstructive shock?
Obstruction of blood flow within circulatory system
Causing decreased blood flow
Eg due to cardiac tamponade, pulmonary embolism, tension pneumothorax
What is distributive shock?
Includes septic shock, anaphylactic shock, neurogenic shock
What is septic shock?
A form of sepsis
Widespread inflammatory response leading to impaired blood flow to vital organs
What is anaphylactic shock?
Life threatening allergic reaction
Immune system overreacts triggering widespread release of histamine
This causes sudden drop in blood pressure and airway constriction
Sharp decrease in blood flow to vital organs
What is neurogenic shock?
Caused by disruption of autonomic nervous system
Leads to vasodilation and decreased vascular tone
This leads to sudden drop in blood pressure and impaired blood flow to vital organs
Often associated with spinal cord or brain injury
What is cardiac tamponade?
Fluid accumulation in pericardial sac (around heart) causing compression of heart chambers
Explain the 4 stages of shock?
1)INITIAL - Initial response to low O2
-Body responds by increasing hr and peripheral vasoconstriction
2)COMPENSATORY - Body can maintain blood pressure to some extent but is working very hard to compensate
3)PROGRESSIVE - Compensatory mechanisms begin to fail
- Organs begin to fail due to inadequate perfusion
4)REFRACTORY - Body can no longer respond to medical treatment and the shock is irreversible
-Severe organ failure and high risk of death
Symptoms of shock?
Tachycardia
Tachypnoea
Pale, cool, clammy skin
Weakness and fatigue
Dizziness
Confusion and disorientation
Low blood pressure
Prolonged capillary refill time (due to peripheral vasoconstriction)
Enlarged pupils
Nausea or vomiting
Decreased level of consciousness
Changes in mental state or behaviour (eg anxious or agitated)
State physiological effects of shock and trauma on the cardiovascular system?
-Hypotension (low blood pressure)
-Tachycardia (in response to the LBP)
-Decreased cardiac output
-Cardiac arrhythmias
-Myocardial ischaemia - inadequate blood supply to heart muscle
… this can manifest as angina or myocardial infarction (HA)
-Peripheral vasoconstriction
-Activation of coagulation system - causing widespread clotting in small blood vessels leading to organ dysfunction and bleeding complications
What is hypovolemia?
Fluid loss from body
What is third spacing?
When fluid accumulates in interstitial spaces rather than remaining in blood vessels or compartments in cells
Causes of hypovolemia?
-Insufficient fluid intake
-Excessive sweating
-Increased urinary output
-Haemorrhage (blood loss)
-Vomiting
-Diarrhea
-Burns (causing fluid loss through damaged skin)
-Third spacing (when fluid accumulates in interstitial spaces rather than remaining in blood vessels)
What is fluid replacement therapy?
Fluid injected into veins
Increases volume of intravascular fluid
Leads to an expansion of circulating blood volume
This fluid moves via osmosis throughout the body replacing lost fluids
What are the 3 different fluid compartments in the body?
Intravascular compartments - blood
Interstitial compartments - surrounds cells of tissues and organs
Intracellular compartments - inside cells
2 types of fluid used for fluid replacement therapy?
Crystalloids
Colloids - eg albumin
What are crystalloids?
Solutions of water and electrolytes used for fluid replacement therapy
What are colloids?
Solutions of liquid containing large molecules (eg protein and starches) used for fluid replacement therapy
The large molecules exert oncotic fluid pressure in intravascular space which helps retain fluid
- Eg albumin
What is albumin?
Natural colloid derived from plasma
Made of protein components of plasma suspended in saline
What are Packed Red Blood Cells transfusions used for?
Restore oxygen carrying capacity and improve tissue oxygen levels in patients with acute blood loss or anaemia
What are Fresh Frozen Plasma transfusions used for?
Used to correct coagulation abnormalities by replenishing clotting factors
What is contained in Fresh Frozen Plasma?
Liquid portion of blood separated from red blood cells and platelets
Contains clotting factors, fibrinogen, albumin and other proteins used for coagulation and haemostasis