Cartilage, Bone and Bone Development

Question 1

Mesenchmayl cell

Answer 1

mulipotent stromal stem cells that can differentiate into a variety of cells including osteoblasts

Question 2

osteocyte

Answer 2

origonate from osteoblasts, maintain bone matric
occupy lacunae
extend filopodia through canaliculi
form gap junctions with neighboring cells

Question 3

osteoblasts

Answer 3

matrix formation, secrete type 1 collagen,
regulate mineralization
positioned in external to osteiod matric
become osteocytes

Question 4

periosteum

Answer 4

a fibrous connective tissue layer that covers outer/external surface of bones
site of insertion of muscles, tendons and ligaments

Question 5

endostium

Answer 5

inner delicate connective tissue surface of bone

lines trabeculae of spongy bone

Question 6

osteoclasts

Answer 6

digest bone and play a role in Ca homeostasis
large multinucleated cells with ruffled edge
originate from pluripotent stem cells of bone marrow

Question 7

diaphysis

Answer 7

middle of long bone

Question 8

epiphysis

Answer 8

end of bones

Question 9

physis

Answer 9

growth plate, epiphyseal plate

hyaline cartilage

Question 10

osteons

Answer 10

functional unit of mature bone

Question 11

osteonal canal

Answer 11

aka haversion canal
canal of blood vessels, and nerves that run through
run longitudinal

Question 12

communicating canal

Answer 12

run transversely

communicate with osteonal canal

Question 13

canaliculi

Answer 13

canals between lacanae of bone

used for communication

Question 14

concentric lamellae

Answer 14

surround haversion canal

Question 15

interstitial lamellae

Answer 15

space between osteons

Question 16

howships lacunae

Answer 16

depression that osteoclasts occupy

Question 17

ruffled border

Answer 17

on osteoclast, facilitates Ca diffusion

has enzymes that will digest bone

Question 18

osteoid

Answer 18

extracellular matrix of bone

Question 19

trabeculae

Answer 19

spongy bone,

aka cancellous