Cartilage And Bone Flashcards
What kind of tissue is cartilage?
Supportive Connective Tissue
Does cartilage contain blood vessels?
Cartilage is Avascular
What does cartilage contain?
Chondroblasts
Chondrocytes
Extracellular matrix
What are chondroblasts
Cartilage cells that produce a semi-solid gel-like matrix which actively divide
What are Chondrocytes
Cartilage cells which are surrounded by matrix and occupy small spaces called lacunae
Functions of cartilage
Supporting soft tissues (ie. trachea and ear)
Gliding surface at articulation
Embryonic model of bone
What are the three types of cartilage
Hyaline
Fibrocartilage
Elastic
Hyaline cartilage
Most common but weakest
Found in: fetal skeletons, ends of articulating bones, in trachea, larynx and nose
Fibrocartilage
Densely interwoven fibres = very durable for shock absorption
Found in: intervertebral disc, pubic symphysis, menisci of the knee
Elastic cartilage
Main feature are the elastic fibres
Fibres can be stretched but will snap back to their original shape
Found in: epiglottis and external ear
Bone make up
Solid connective tissue
Osteocytes (mature bones)
Extracellular matrix
Covered by Periosteum (dense irregular CT)
Functions of bone
Support and Protection
Movement
Hemopoiesis
Storage of mineral and energy reserves
Different classifications of bones
Long bones
Short bones
Flat bones
Irregular bones
Gross anatomy of a long bone
Diaphysis
Epiphysis
Metaphysis (contains epiphyseal plate)
Articular cartilage
Medullary cavity (space in diaphysis, contains yellow marrow in adults)
Periosteum
Endosteum
Cells of Bone (4)
Osteoprogenitor cells
Osteopblasts
Osteocytes
Osteoclasts
Osteoprogenitor cells
Stem cells which produce more stem cells or osteoblasts
Found in: Endosteum and Periosteum
Osteoblasts
Secretes bone matrix (osteoid)
Once trapped in matrix it becomes an osteocytes
Osteocytes
Mature bone cells
Are within lacunae
They maintain matrix and mechanical stress on bone
Osteoclasts
Large and multinuclear
Derived from bone marrow
Dissolves bone matrix; removes bone and releases Ca
Bone matrix
Organic (1/3): cells, collagen fibres, ground substance
Inorganic: mainly hydroxyapatite
Hydroxyapatite
The main inorganic component of bone matrix
Calcium phosphate and calcium hydroxide
The crystals deposit around collagen fibres which harden the bone matrix
Two types of bone
Compact bone
Spongy bone
Compact bone
AKA: dense, cortical
Solid, relatively dense
External surfaces of long and flat bones
Spongy bone
AKA: cancellous, trabecular
Open lattice of narrow plates called trabeculae
Internal surface of bones
Porous
Flat bone structure
Spongy bone sandwiched between 2 layers of compact bone
Compact bone (microscopic anatomy)
Osteon (the big round layered thing)
Central canal, carries BV and nerves
Concentric lamellae, rings of bone around the central canal
Osteocytes, housed in lacunae between concentric lamellae
Canaliculi, interconnecting channels within bone that extend between lacunae, allows osteocytes to connect and communicate