Cards Flashcards
Least interactions of statin
Pravastatin has the least interactions. atorvastatin, lovastatin, and simvastatin are primarily metabolized through the cytochrome P-450 3A4 isoenzyme and interact with diltiazem. Crestor interacts with CYP2C9 and can effect warfarin levels. Use atorvastatin in HIV patients
Management of mitral stenosis
Severe stenosis (>10 mmHg gradient, LA enlargement) is best managed with balloon valvuluplasty IF favorable anatomy (no calcification, no thickening, good mobility, no subvalvular thickening) and only mild regurgitation, otherwise need valve replacement
Evaluation of cardiac risk in younger woman
Best score is the Reynolds risk score as Framingham tends to under-estimate risk
Cheyene stokes respiration in heart failure
Medically optimize first, including dieresis. If persists can use servo controlled ventilation.
Murmur and need for echo
If: >3/6 diastolic continuous holosystolic late systolic click if it is radiating to the neck or back
Repair MR?
> LV 45 mm
LVEF
Repair a AAA?
Greater than 5.5 cm or >0.5 cm in 1 year growth
Bridge anticoagulation?
- Embolic stroke or systemic embolic event within the previous 12 weeks
- Mechanical mitral valve
- Mechanical aortic valve and additional stroke risk factors
- Atrial fibrillation and very high risk of stroke (eg, CHADS2 score of 5 or 6, stroke or systemic embolism within the previous 12 weeks)
- Venous thromboembolism (VTE) within the previous 12 weeks
- Recent coronary stenting
- Previous thromboembolism during interruption of chronic anticoagulation
Indications for BiV pacing
Class III-IV symptoms, LVEF 120
OR
Class II, LVEF 150
Constrictive pericarditis echo findings
shifting of the ventricular septum to and fro, not seen in restrictive cardiomyopathy
Anti-coagulate in mitral stenosis?
If they have Afib, do not go by Chads2 score
LA >5.5 cm
Previous embolic event