Cardiovascular System Flashcards

1
Q

What is the function of the cardiovascular system?

A

To maintain homeostasis of ISF

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2
Q

What is the function of the heart?

A

To generate movement

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3
Q

What is the function of the vasculature?

A

To create a pathway for the blood

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4
Q

What is hematocrit?

A

The % of blood that is RBCs

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5
Q

What is flow rate?

A

The AMOUNT of blood that travels through the vessel at a given time.

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6
Q

What makes blood flow?

A

The pressure gradient

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7
Q

What is velocity of flow?

A

The DISTANCE traveled through the vessel during a given time.

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8
Q

Which vessel has the highest pressure?

A

Aorta

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9
Q

Which vessel has the lowest pressure?

A

Vena cava

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10
Q

Which vessels have the most change in pressure?

A

Arterioles

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11
Q

What influences the rate of flow the most?

A

Radius of the vessel

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12
Q

What is the membranous sac encasing the heart?

A

Pericardium

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13
Q

What lubricates the heart so it does not stick when it contracts?

A

Pericardial fluid

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14
Q

What is the pacemaker of the heart?

A

SA Node

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15
Q

Explain the funny current.

A

The influx of Na+ when reaching the threshold of HYPERpolarization.

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16
Q

Refractory period of the heart means?

A

Another heart beat cannot be stimulated.

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17
Q

What is contractility?

A

Strength of contraction

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18
Q

____ from postganglionic neurons and _____ from adrenal medulla bind to ___ receptors on cardiac myocytes.

A

Norepinephrine, epinephrine, beta1-adrenergic

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19
Q

During diastole the heart is contracted or relaxed?

A

Relaxed

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20
Q

During diastole are the AV and SL valves open or shut?

A

AV: open / SL: shut

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21
Q

During systole are the AV and SL valves open or shut?

A

AV: shut / SL: open

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22
Q

Which valves are closing during the 1st heart sound?

A

Atrial-ventricular valves (AV)

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23
Q

Which valves are closing during the 2nd heart sound?

A

Semilunar valves (SL)

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24
Q

What is the electrical conduction pathway?

A
  • SA node
  • AV node
  • Bundle of His
  • Bundle branches
  • Purkinje Fibres
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25
What does an ECG measure?
The electrical changes of the whole heart during a heartbeat
26
What does an action potential measure?
The electrical changes of one myocardium cell
27
What repolarizes the heart?
K+
28
What does the P wave stand for (ECG)?
Atrium depolarization
29
What does the QRS wave stand fro (ECG)?
Ventricular depolarization
30
What does the T wave stand for?
Ventricular repolarization
31
Why do you not see atrium repolarization on an ECG?
Because the ventricular depolarization is so strong, it overtakes the ECG's readings.
32
What is active hyperemia?
Increase in flow because of high demand - When there is less O2, more CO2 eg. exercising
33
What is reactive hyperemia?
The increase of blood flow following an occlusion (ischemia) | eg. leg falling asleep
34
What is myogenic autoregulation?
Constricting/dilating of the vessels due to stretch, | - Stretch-activated channels in the SM of arterioles causes these channels to intake Ca2+ to constrict again.
35
What are 3 examples of local control in the cardiovascular system?
- active hyperemia - reactive hyperemia - myogenic autoregulation
36
What is the AV node?
- controls the heart rate | - slowing the electrical signal from the SA node
37
What is the SA node?
- group of cells on the right atrium - pacemaker - generates actin potentials
38
At what point is the heart most full of blood?
End of diastole
39
What does end-diastolic volume mean?
The volume of blood in the heart at the end of diastole. (full of blood)
40
What does end-systolic volume mean?
The volume of blood in the heart at the end of ejection (systole).
41
What is stroke volume?
The amount of blood that is ejected from the left ventricle
42
Which vessel has the smallest diameter and thinnest walls?
Capillaries
43
What are the three types of capillaries?
- continuous - fenestrated - sinusoid
44
Does blood move slowly or quickly through capillaries?
The slowest rate.
45
What is bulk flow?
mass movement of fluid between blood and ISF
46
What is the most compliant vessel?
Veins
47
Resistance, diameter of veins?
Low resistance, large diameter
48
What kind of muscle do veins use? Sympathetic or parasympathetic vasoconstriction?
Smooth muscle, sympathetic
49
Where does most exchange take place?
Capilleries
50
What are the 2 Starling forces?
- hydrostatic pressure | - osmotic pressure
51
For a sympathetic contraction epinephrine and norepinephrine bind to what kind of receptors on the myocyte cells?
Beta1-adrenergic receptors
52
Is the relaxed heart in diastole or systole? The contracted heart?
Relaxed - diastole | Contracted - systole
53
During isovolumetric contraction what part of the heart is filled with blood?
The ventricles
54
During vigorous exercise where does most of the blood fro the heart go to?
The muscles
55
What is the function of the barorecptors?
To maintain homeostasis of blood pressure
56
Where are the two locations of baroreceptors?
Aortic arch and carotid arteries
57
What is the heartbeat initiated by?
The conducting system of the heart | - all of its nodes control itself, heart can keep beating after you die
58
Depolarization during the action potential of a pacemaker cell in the SA node is due to an
influx of Ca2+
59
What is hemostasis?
Blood clotting
60
What is hematopoiesis?
Blood cell production
61
How are RBCs destroyed? And after roughly how many days?
~ 120 days | by spleen
62
What is anemia?
Decreased ability to carry O2 in blood
63
Where do platelets come from?
The are fragments of MEGAKARYOCYTES in the bone marrow
64
What converts fibrinogen to fibrin?
thrombin