cardiovascular system Flashcards
3 components to cv system
- heart : pump, driving force
- blood vessels or vascular system : passageways, interconnected tubes
- blood : medium being pumped through passageways
plasma
blood minus the cellular components
blood volume
whole blood ~ 8 % of body weight
4-5 L for women
5-6L for mn
fluid connective tissue
-components
plasma 55%
formed elements 45%
plasma proteins
albumins 60% - osmotic pressure, transport
globulins 36% - transport, immune
fibrinogen 4% blood clotting
hematopoiesis
blood cell formation in red bone marrow ~100 billion new cells/day
-continuously proliferate and differentiate
types of hematopoiesis
erythropoiesis - erythrocyte production
thrombopoiesis- platelet production
leukopoiesis - leukocyte production
erythrocyte
small, biconcave disc, thin walled but membrane strong and flexible
-no nucleus or organelles in mature cells, contain large amounts of hemoglobin
hemoglobin
- 4 globin chains (2 alpha, 2 beta)
- 4 heme groups (each heme has 1 iron at its core that can can bind to 1 oxygen)
- can bind to O, CO2, H+, NO2
platelets
- smaller than erythrocytes, disc shape, no nucleus
- larger cell (megakaryocyte) fragments into 1000-3000 platelets
- each platelet has a plasma membrane and many vesicles
watch doctor matt and mike vids
cardiac output
volume of blood pumped out of each ventricle per unit time (mL/min or L/min)
composed of :
- heart rate (HR) (BPM)
- stroke volume (SV) : volume each ventricle ejects during each beat (mL/beat) end diastolic volume - end systolic volume = stroke volume