Cardiovascular Physiology Part G: Circulatory Shock Flashcards
Circulatory Shock
inadequate blood flow (⇓ O2, nutrients to cells)
Hypovolemic Shock
- ⇓ blood volume
- due to: blood loss, severe burns, diarrhea, vomiting
Vascular Shock
- blood volume normal, but vessels expanded
- due to: systemic vasodilation of blood vessels ⇒ ⇓ bp
Anaphylactic Shock
- example of vesicular shock
- allergic reactions
- due to: lots of histamine released from mast cells
Septic Shock
- example of vesicular shock
- due to: bacterial toxins
Cariogenic Shock
- example of vesicular shock
- pump failure ⇒ ⇓ CO
- heart cannot sustain blood flow
3 Stages of Shock
- Compensatory
- Progressive
- Irreversible
Which stage of shock has mechanisms to restore homeostasis and involves baroreceptors, chemoreceptors and schema (lack of O2) of medulla?
Compensatory
Compensatory stage of shock
trigger SNS, which……
- ⇑ HR, generalized vasoconstriction (except to heart, brain) = ⇑ bp
- ⇓ blood flow to kidneys triggers renin release - get angio II, aldosterone, ADH release ∴ vasocon, ⇑ Na+, H2O retention (maintain blood volume), ⇑ thirst
Which stage of shock has mechanisms inadequate to restore homeostasis- requires intervention?
Progressive
What happens in the progressive stage of shock?
- ⇓ CO ∴ ⇓ bp in cardiac circulation ∴ ⇓ cardiac activity
- ⇓ blood to brain ⇒ ⇓ cardiovascular control
- damage to viscera due to ⇓ blood flow, especially kidneys (can lead to renal failure)
What happens in the Irreversible stage of shock?
- ⇓ CO ⇒ too little blood to heart ⇒ ⇓ CO
2. self-perpetuating cycle - leads to death