Cardiovascular Physiology I Flashcards
Valve from the r. atrium to the r. ventricle
Tricuspid valve
Valve from the l. atrium to the l. ventricle
Mitral/bicupsid
Valve exiting the l. ventricle
Aortic
Valve exiting the r. ventricle
Pulmonary
Direction of blood flow in heart
Vena Cava - RA - RV pulmonary circulation - LA - LV - Aorta - systemic circulation
Diastole vs systole
Ventricular relaxation; ventricular contraction.
Endocardium
Thin inner layer made up of endothelial cells. Acts as a blood-heart barrier.
Myocardial layer
Middle layer, composed of cardiac muscle and constituting the bulk of the heart wall. Generates the force for pumping function and conducts impulses.
Epicardium
Thin external layer, composed of mesothelial cells, fat, and connective tissues. Provides mechanical support and important for repair and development.
Cardiac muscle as syncytium
Many fused cardiac cell, connected by intercalated discs (gap junctions and desmosomes). Rich in mitochondria and composed of many microfibrils.
2 pumping cells of the heart
Contraction of cardiac muscles is triggered by action potentials. 1% conductive, 99% contractile.
Cardiac action potential
Transient reversible electromagnetochemical wave-front responsible for the generation of the cardiac impulse.
Pacemaker cell response
Slow AP propagation, absent phase-1, Vm -60mV
Contractile mycoytes response
Fast propagation, phases 0-4 present, resting Vm of -90mV.