Cardiovascular interventions Flashcards
manual defib
restores the electrical function of the heart by overriding undesirable ventricular rhythms
delivers randomly timed electrical current to restore sinus rhythm
synchronised cardioversion
used when pt is presenting with narrow complex tachycardias
requires sedation of the pt
lower joule setting than defib
transutaneous cardiac pacing
delivery of shock through the wall of the pts chest to stimulate contraction
indicates to use on bradycardic pts who are symptomatic
thrombolytic therapies
therapeutic drugs that inhibit thrombus formation or work to reduce the size of a thrombus that has formed
aim is to restore perfusion to ischaemic area
thrombolytic therapies used
streptokinase
urokinase
tissue plasminogen activator
recombinant, or genetically engineered, tPA
precautions of thrombolytic therapies
clotting disorder, history of internal bleeding, pregnancy, endocarditis, advanced age, recent surgery or injury, poorly controlled hypertension, diabetic retinopathy
streptokinase
antigenic
binds with free circulating plasminogen to form a complex that can convert additional plasminogen to plasmin
urokinase
used more often for peripheral intravascular thrombus and occluded catheters
indicated for massive pulmonary embolism
thrombolytic agent that is produced in renal parenchymal cells
tissue plasminogen activator (tPA)
synthesized and made available by cells of the vascular endothelium
physiologic thrombolytic agent responsible for most of the body’s natural efforts to prevent thrombus formation
recombinant or genetically engineered r-PA
works more rapidly and has a lower bleeding risk than the first generation agent alteplase
non pharmacological reperfusion therapies
CAGS
angioplasty
stenting
CAGS
blood supply restored to an ischaemic area by grafting in another artery
surgical equivalent of collateral circulation
ideal for pts with multiple occlusions
angioplasty (PTCA)
cathetor inserted into artery groin or axilla
balloon on cathetor
balloon inflated to increase diameter of lumen
complications of angioplasty
abrupt closure of the dilated coronary artery within the first few hours after the procedure
given with anticoagulant drug to minimise clotting post procedure
stents
manufactured support inserted into a natural passage in the body to prevent, or counteract a disease-induced, localised flow constriction
can be bare metal or drug eluting