Cardiovascular: Hypertension Flashcards
What is BP target for <80 yearss old?
<140/90
What is BP target for <80 years old with
- atheosclerotic CV
- diabetes with kidney/eye/cerebrovascular disease
<130/80
What is BP target for renal disease?
<140/90
What is BP target for:
- CKD
- Diabetes
- Proteinuria
<130/80
What is BP target for type 2 diabetic (without complications) in <80 and >80
<80= <140/90 (only lower if complications) >80= <150/90
In what circumstances would you treat (medically) stage 1 hypertension (140/90)?
All >80 Only <80 if: - target oran damage e.g. CVT/ventricular hypertrophy/retinopathy - CVD and QRISK >10% - renal disease - diabetes
What is classed as stage 2 hypertension
160/100
What is stage 1 and 2 treatment for <55 (or type 2 diabetes)
ACE or ARB
Step 2: CCB or thiazide like diuretic
What is step 1 and 2 management for black african/caribbean or >55?
- CCB
2. ACE or ARB or thiazide like diuretic
What is target BP for HTN in pregnancy?
<150/100 chronic
<140/90 chronic and if target organ damage or given birth
What anti-hypertensives are used in pregnancy
Labetalol
Methyldopa
MR nifedipine
Name side effects of ACEi
Dry cough angioedema hyperkalaemia Anaphylactoid reactions Renal nephrotoxic in AKI Cholestatic jaundice - LFT 3xUL ulcers Taste disturbancee hypoglycaemia
What are side effects of calcium channel blockers
oedema /swelling flushing headaches gingival hyperplasia erectile dysfunction
which CCB are used in HTN and why?
Dihydropyridines - more selective for the vasculature
- amlodipine/felodipine/lacidipine/lercandipine/nifedipine
What interactions are involved with CCB?
Enzyme inhibitors can increase CCB concentrations e.g. grapefruit juice, ssodium valp, fluconazole, cimetidine, macrolides, quinolones, omeprazole
