Cardiovascular Function & Perfusion Flashcards
Where is the heart located?
In the Mediastinum
Serous layer of the heart, it’s function is to protect the heart =
Epicardium
The muscle layer of the heart that’s function is for pumping =
Myocardium
This layer of the heart makes up the lining of the heart and heart valves =
Endocardium
The sac that surrounds the heart =
Pericardium
The sac that surrounds the heart =
Pericardium
What are the names of the different layers of Pericardium?
Visceral Pericardium
Parietal Pericardium
This layer of Pericardium covers the heart’s surface =
Visceral Pericardium
This layer of the Pericardium makes up the lining of the Pericardial Sac =
Parietal Pericardium
What does the Interventricular Septum do?
Separate the Ventricles
What does the Interatrial Septum do?
Separate the Atria
What joins Arteries and Capillaries?
Arterioles
What joins Capillaries and Veins?
Venules
Between the Arteries and Veins, which carries high-pressure blood and low-pressure blood?
Arteries = High-Pressure Blood
Veins = Low-Pressure Blood
These permit gas exchange, the transfer of nutrients and the removal of waste between blood and the fluid of tissues =
Capillaries
What is the outer-most layer of the blood vessels called?
Tunica Adventitia
What is the middle layer of the blood vessels called?
Tunica Media
What is the inner-most layer of the blood vessels called?
Tunica Intimae
The normal cardiac output in a healthy adult at rest is-
5 to 6 L/min
The force that the Myocardium generates during contraction =
Contractility
What does a Heart Murmur indicate?
Turbulent blood flow through normal or abnormal valves
An abnormal heart sound that’s typically heard over the left sternal border (Grating Sound) =
Pericardial Friction Rub
What are the different types of Myocardial Infarction called?
ST Elevational Myocardial Infarction (STEMI)
Non-ST Elevation Myocardial Infarction (NSTEMI)
What is the difference between Stable Angina and Unstable Angina?
Stable Angina is Chest Pain that has a trigger (Stress or Exercise)
Unstable Angina is Chest Pain that occurs without a trigger (Occurs at rest)
How can Angina be treated?
Rest
Nitroglycerin
STEMI, NSTEMI, Stable Angina, and Unstable Angina can all be caused by-
Coronary Artery Disease
An Acute Coronary Syndrome can cause-
A STEMI, NSTEMI, or Unstable Angina
A STEMI occurs due to-
An abrupt disruption of blood flow to an area of the heart
An NSTEMI has characteristics that are comparable to-
Unstable Angina
What is the difference between a NSTEMI and Unstable Angina?
Cardiac Markers are Elevated with an NSTEMI
What are the Risk Factors of Coronary Artery Disease?
Sedentary Lifestyle, Sex, Family History, Lack of Sleep, Hypertension, Diabetes, Race/Ethnicity, Homocysteine Levels, Lipid Levels, Smoking, Obesity, Stress, Age
What is Coronary Artery Disease?
When plaque narrows the arteries and blocks blood flow to the heart
After enough time passes while untreated, what can Coronary Artery Disease cause?
A Weakened Heart, Heart Failure, Arrhythmia
Mental health disorders can contribute to Cardiac Disorders. True or false?
True
What are the initial symptoms of Coronary Artery Disease?
It’s Asymptomatic at first
What’s the most common complaint of CAD?
Angina
What are some of the symptoms of CAD?
Tightness, Fullness, Pressure in Midsternal Area, Stable & Unstable Angina
Pain radiates to the left arm, neck, jaw, or back
Diaphoresis, Dizziness, N/V, SOB, Lightheadedness, Weakness
What types of pt’s experiencing an MI may not experience Angina (the Angina could also be atypical) =
Females, Elderly, People with Diabetes
What does the Parietal Pericardium attach to?
The Great Vessels, Diaphragm, Sternum, and Vertebral Column
What deoxygenated blood uses the Superior Vena Cava to get to the heart?
Deoxygenated blood that comes from the head and neck
What deoxygenated blood uses the Inferior Vena Cava to get to the heart?
Any deoxygenated blood that doesn’t come from the head and neck
What are the bodies Major Arteries?
Common Carotid Arteries
Brachial Arteries
Radial Arteries
Ulnar Arteries
Common Iliac Arteries
Femoral Arteries
Arch of the Aorta
Abdominal Aorta Artery
What are the bodies Major Veins?
Internal Jugular Veins
Superior Vena Cava
Inferior Vena Cava
Cephalic Veins
Basilic Veins
Common Iliac Veins
Femoral Veins
Where do the Coronary Arteries originate from?
From the base of the aorta just above the Aortic Valve
The Right and Left Coronary Arteries deliver oxygenated blood to the rest of the body during-
Diastole
What are the Left Coronary Artery’s branches?
Left Main Coronary Artery
Left Anterior Descending Artery
Circumflex Artery
What are the Right Coronary Artery’s branches?
Marginal Artery
Posterior Descending Artery
What are the factors that affect Cardiac Output?
Vasoconstriction, Compliance of the Arteries, Arterial Pressure, the amount of blood entering the heart from the veins, exercise
How should you auscultate for S3 and S4 sounds?
With the bell of the stethoscope
S3 sounds can be normal in patients who are-
Children or adults up to 40 years old
An S3 sound can indicate-
Heart Failure + Decreased Ventricular Compliance
What is an S4 sound caused by?
Decreased Ventricular Compliance
What can decreased ventricular compliance be caused by?
Hypertension, Aortic Stenosis, CAD, or Cardiomyopathy
What is Cardiomyopathy?
Heart Enlargement
What are the different types of Heart Murmurs?
Diastolic Murmurs
Systolic Murmurs
When can Diastolic Murmurs be heard?
Between S2 and S1
When can Systolic Murmurs be heard?
Between S1 and S2
What is a Pericardial Friction caused by?
Inflammation, Infection, or Infiltration in the Pericardial Sac
How are Pericardial Friction Rubs treated?
By treating what’s causing the problem
What is Atherosclerosis?
The closing or narrowing of Arteries
When does Plaque Formation occur in a person’s arteries?
Begins in childhood, continues into adulthood
What can cause Stable Angina to occur during exercise or stress?
When the body is undergoing exercise or stress, the body needs more blood to function properly. When the arteries are clogged with plaque, the amount of blood that’s needed isn’t available
Ischemia =
Not enough blood is getting to where it needs to be
When does CAD begin to develop?
During childhood
Are Homocysteine levels a modifiable factor?
Yes
What chronic diseases cause CAD?
Hyperlipidemia, Thyroid Disease, Depression, Joint Pain, BMI of 30 or higher, Gout, Osteoarthritis, Cancer
Female pt’s suffering from an MI may present with-
Extreme Fatigue, Dizziness, Abdominal Pain, Nausea, Pressure in Chest
If a pt with Diabetes has an MI, how might their pain differ from those who don’t have diabetes that have an MI?
Their pain is less severe and can their pain can occur in atypical locations
Where are some atypical locations that a pt with diabetes who is suffering from a MI may feel pain?
Right side of chest + Epigastric region + Back of neck + May experience none
What types of pt’s may suffer from an MI, have no chest pain, but still have N/V, SOB, Diaphoresis, and Syncope?
Older Adults over the age of 85 + Diabetic Pt’s (Due to nerve damage, may not feel pain)
What is it called if you are passing out?
Syncope
What are the lab studies that are important to keep in mind when thinking about CAD?
Cholesterol
Homocysteine
C-reactive Protein
Cardiac Enzymes
What are the different types of Cholesterol lab studies?
Total Cholesterol
High-Density Lipoprotein (LDL)
Low-Density Lipoprotein (HDL)
What are the different types of lab studies for Cardiac Enzymes?
Troponin 1
Troponin T
Creatine Kinase-MB (CK-MB)
The total cholesterol can be described as-
The total amount of HDL and LDL combined
What is LDL?
Bad cholesterol, primary source of plaque buildup in the arteries
What is HDL?
Good cholesterol, carries cholesterol away from the arteries
What breaks Homocysteine down into other substances that the body needs?
Vitamin B12
Vitamin B6
Folic Acid
By the time that Homocysteine is broken down, how much should still be left in the blood?
Very little
What problems can excess Homocysteine cause?
Damage to the lining of the arteries
Blood Clots
Blockages in the Blood Vessels
What does C-reactive protein do?
It detects inflammation in the body
Troponin 1 and T are both highly sensitive to-
Cardiac Injury
When can Troponin 1 and T be found in a pt’s blood serum?
Within 4 hours from the onset of acute MI manifestations
How long does it take for Troponin to peak?
Within 24-48 hrs
How long can Troponin levels remain elevated?
Days
CK-MB is an enzyme specific to the-
Heart
After an MI, CK-MB can be detected within-
4 hrs
After an MI, CK-MB levels will peak within-
24 hrs
After an MI, CK-MB will return to normal within-
48-72 hrs
This lab study can be useful for detecting re-infarction in pt’s =
CK-MB
ST Segment Elevation, ST Depression, and T Wave Inversion all suggest-
CAD
Outside of an EKG, what are the different ways to diagnose CAD?
Cardiac Catheterization
Stress Tests
X-Ray