Cardiovascular Drugs Flashcards
Anti-hypertensive Drugs?
Vasodilators Angiotensin Receptor Blockers B-Blockers Calcium Antagonists Diuretics
Diuretic mechanism for treatment of hypertension?
Inhibits reabsorption of water and Na+ in the loop of Henle or distal tubule –> reduces volume –> reduces BP
Diuretic example for hypertension?
Bendrofluazide
Bendrofluazide
Thiazide diuretic
Used for treatment of hypertension
Side effects - tiredness, arrthymias, diabetes, gout
B-blocker mechanism for treatment of hypertension?
Block B1 receptors - blocks stimulation of Gs
B-blocker example for hypertension?
Atenolol
Atenolol
B-blocker
Used for treatment of hypertension
Side effects - tiredness, cold peripheries..
Hypertensive drug never to be used in a patient with asthma/COPD?
B-blockers
Ca+ channel antagonist mechanism for treatment of hypertension?
Blocks L-type channels - decreased calcium entry, decreased contractility
Ca+ channel antagonist example for hypertension?
Amlodipine
Amlodipine
Ca+ channel antagonist
Used for treatment of hypertension
Side effects - ankle swelling
Vasodilator Drug Class
Alpha Blockers
ACEI
Alpha blocker mechanism for treatment of hypertension?
Blocks vascular alpha1-adrenoceptors - decreased TPR and MABP
Alpha blocker example for hypertension?
Prazosin
Prazosin
Alpha blocker
Used in treatment of hypertension