Cardiovascular Drugs Flashcards
Anti-hypertensive Drugs?
Vasodilators Angiotensin Receptor Blockers B-Blockers Calcium Antagonists Diuretics
Diuretic mechanism for treatment of hypertension?
Inhibits reabsorption of water and Na+ in the loop of Henle or distal tubule –> reduces volume –> reduces BP
Diuretic example for hypertension?
Bendrofluazide
Bendrofluazide
Thiazide diuretic
Used for treatment of hypertension
Side effects - tiredness, arrthymias, diabetes, gout
B-blocker mechanism for treatment of hypertension?
Block B1 receptors - blocks stimulation of Gs
B-blocker example for hypertension?
Atenolol
Atenolol
B-blocker
Used for treatment of hypertension
Side effects - tiredness, cold peripheries..
Hypertensive drug never to be used in a patient with asthma/COPD?
B-blockers
Ca+ channel antagonist mechanism for treatment of hypertension?
Blocks L-type channels - decreased calcium entry, decreased contractility
Ca+ channel antagonist example for hypertension?
Amlodipine
Amlodipine
Ca+ channel antagonist
Used for treatment of hypertension
Side effects - ankle swelling
Vasodilator Drug Class
Alpha Blockers
ACEI
Alpha blocker mechanism for treatment of hypertension?
Blocks vascular alpha1-adrenoceptors - decreased TPR and MABP
Alpha blocker example for hypertension?
Prazosin
Prazosin
Alpha blocker
Used in treatment of hypertension
ACEI mechanism for treatment of hypertension?
Blocks the conversion of angiotensin I - angiotensin II
ACEI example for treatment of hypertension?
Lisinopril
Lisinopril
ACEI
Used in treatment of hypertension
Side effects - dry cough
NEVER USE IN PREGNANCY
Class of diuretics that act on the distal tubule
Thiazide diuretics
Class of diuretics that act on the thick ascending loop of Henle
Loop diuretics
Has side effects that include
tiredness, arrthymias, diabetes, gout
Bendrofluazide
Has side effects that includes tiredness and cold peripheries
B-blockers
Atenolol
Has side effects including ankle swelling
Amlodipine ( ca2+ channel antagonisti)