Cardiovascular Flashcards
Pericarditis presentation
- Central chest pain worse lying flat
- ?Fever
- ?Pericardial rub
- ECG- saddle shaped
Diastolic Murmurs
- Aortic Regurg
- Mitral Stenosis
Heart Failure Management
- Acute- sit up, morphine, GTN, furosemide, NIV
- ACEi/ ARB, Aspirin, Atorvastatin, Beta blocker, Diuretic
- Avoid NSAIDs, CCB!
Features of Aortic Stenosis
- Murmur- upper R sternal border –> carotids. Systolic crescendo-decrescendo
- Sx Triad- Chest pain, SOB, syncope
- Cause- esp senile calcification
- Tx- valve replacement
Features of Mitral Regurgitation
- Murmur- Apex –> axilla. Pansystolic rumble. S
- x- palpitations, SOB
- Causes- senile, infectiove endocarditis, marfans
- Tx- valve replacement
Syncope differentials
- Orthostatic BP- hypovolaemia, drug induced, PD, diabetic neuropathy
- Neurally mediated- Carotid sinus sensitivity, situational
- Neurocardiogenic- vasovagal
- Cardiac- arrhythmias
- Cardiac- structural
- Cardiocascular- MI, PE, aortic dissection
- Non-syncopal- CVA, metabolic, epilepsy, intoxication, falls
Heart Failure CXR findings
- Alveolar oedema (bats wings)
- kurley B lines
- Cardiomegaly
- Dilated upper lobe vessels
- Effusion (pleural)
Management of ACS
- ABCDE
- Morphine + metoclopramide
- Aspirin 300 mg 1 dose –> 75mg
- GTN spray
- Clopidogrel/ ticagrelor
- LMWH- Fundoparineux
- Revascularisation- PCI/ CABG
Hypertensive Crisis and Tx
- Hypertensive crisis= BP >200/120
- Absence of end organ damage –> PO
- End organ damage –> IV hydralazine/labetalol/nitroprusside/ GTN
Pericarditis treatment
NSAIDs, colchicine
Wolf-Parkinson-White ECG
Short PR interval and delta wave
Degrees of Heart Block and ECG features
- 1st- Consistently prolonged PR
- 2nd degree Mobitz 1- PR progressively lengthened –> dropped QRS
- 2nd degree Mobitz 2- Prolonged PR, QRS regularly dropped
- 3rd degree- no relation between p waves and QRS ==> Tx: pacemaker
Features of cardiac syncope
- Sudden onset and recovery
- No prodrome
- Sx- palpitations, SOB, chest pain FHx????
Infective Endocarditis management
- ABx- ampicillin + flucloxacillin + gentamicin IV
- Surgical debridement/ valve replacement
Types fo ACS
- Unstable Angina
- NSTEMI
- STEMI
Causes of sudden cardiac death
- Coronary artery disease
- Cardiomyopathies- Dilated, hypetrophic (children/athletes), restrictive, arrhythmogenic R ventricular cardiomyopathy
- Inherited arrhythmia syndromes- long QT, CPVT
- Valvular heart disease
- Channelopathies eg Brugada syndrome
What is this ECG?

Atrial Fibrillation
Heart Failure Ix
ECG, BNP, ECHO
Symptoms of RHF
PeRipheral Oedema:
- Ankle swelling
- Ascites
- Nausea
- Anorexia
- Facial engorgement
- Epistaxis
Signs of familial hyperlipidaemia
- Tendon xanthoma
- Corneal arcus
- Xanthelasma
- Palmar xanthoma
- Tuberoeruptive xanthoma
- Eruptive xanthoma
- Lipaemia retinalis
Narrow complex tachycardias + Tx
- AF –> beta blocker/ diltiazem –> digoxin –> amiodarone
- SVT –> vagal manoevers –> adenosine 6mg –> 12mg –> 12mg Atrial flutter –> HELP! and beta blocker
Treatment of bradycardia
- Atropine 500 micrograms IV (repeat max 3mg)
- Isoprenaline
- Adrenaline
- Transcutaneous pacing
What is the Cushing’s reflex?
Raised ICP –> bradycardia and hypertension
Features making SVT more likely than sinus tachycardia
- ++HR and drops suddenly
- Rate doesn’t vary with respiration
- Hard to see p waves
- Responds to vagal manoevers
- ++ Sx and palpitations
Broad complex tachycardias + Tx
- VT –> amiodarone/ D/C cardioversion. PULSE?
- AF with BBB
- Torsades de Pointes –> Magnesium 2g IV over 10mins
Presentation of Infective Endocarditis
- New heart murmur
- Fever + signs of sepsis
- Immune complex deposition- vasculitis, AKI, glomerulonephritidies, Roth spots, splinter haemorrhages, osler nodes
- Embolic phenomena- Abscesses, janeway lesions
Infective Endocarditis diagnostic criteria
Dukes:
- Major: +ve blood culture x2, + ECHO
- Minor: Predisposed, Fever >38, Vascular/ immunological signs, +ve blood culture/ ECHO that don’t meet criteria.
- Dx: 2x major OR 1x major and 3x minor OR 5x minor
What is QRISK2?
- 10 year CVD risk. >10% –> treat with statins. Involves:
- Age
- Sex
- Ethnicity
- Post-code
- Smoking status
- DM
- MI
- <60y
- CKD
- BP
- RA
- BMI
MI Diagnostic criteria
Troponin 99th Percentile + rise or fall of 20% and 1 of the following:
- Ischaemic Sx
- ECG- ST elevation/ new LBBB
- ECG- pathological Q wave
- Imaging- loss of viable myocardium
- Angiography- intracoronary thrombus
Hypertension Stages
- >140/90 (135/85)
- >160/100 (150/95)
- >180/110. EMERGENCY
Features of Aortic Regurgitation
- Murmur- LSE, ++ leaning forward. Early diastolic decrescendo.
- Sx: SOB, collapsing pulse, palpitation, syncope
- Causes: Infective endocarditis, Marfan’s
- Tx: ACEi, valve replacement
Symptoms of LHF
PuLmonary Oedema:
- SOB, orthopnoea, PND
- Poor exercise tolerance
- Nocturnal cough +/- pink frothy sputum
- Cold peripheries
- Weight loss
Definition of Hypotension
SBP <100 mmHg
Types of Hyperlipidaemia
- Common primary (70%)
- Familial primary hyperlipidaemia
- Secondary hyperlipidaemia- Cushing’s, hypothyroid, nephrotic syndrome, renal failure, drugs eg corticosteroids
Systolic Murmus
- Aortic Stenosis
- Mitral Regurg
Target BP
- <80y= 140/90
- >80y= 150/90
- Established CVD, DM + kidney/eye disease= 130/80
Secondary causes of hypertension and Ix
- Renal artery stenosis –> urine dip
- Phaeochromocytoma –> urine catecholamines and plasma metanephrines
- Conn’s
- Thyroid dysfunction –> TFTs
- Acromegaly –> IGF-1
- Cushings –> urinary free cortisol and dexamethasone suppression
- Obstructive Sleep apnoea
Treatment of hyperlipidaemia
- 1st = lifestyle
- 2nd= atorvastatin
- 3rd= fibrates
ACS Post-Hospital discharge
- ACEi/ Aspirin
- Beta blockers/ BP<140
- Cholesterol (atorvastatin)
- Diet/ Diabetes control/ Driving (stop 1-4w)
- Education/ Exercise
- Cardio rehab
Rheumatic Fever management
Bed rest, analgesia, Ben Pen
Definition of postural hypotension
BP drop >20/10mmHg measured 1 min after standing from lying position
Features of Mitral Stenosis
- Murmur- Apex, ++ rolling patient to side. Mid-diastolic rumble.
- Sx: SOB, malar flush, haemoptysis, chest pain, palpitations
- Causes: Esp rheumatic fever
- Tx: AF control, diuretics, valve replacement
Time course of Rheumatic fever
Pharyngeal infection with Strep –> RF 2-4w later
AF management
- Rhythm control <48h- D/C electrical shock or amiodarone/ flecainide
- Rate control- beta blocker/ CCB (verapmil, diltizem)
- Anticoagulation based on CHA2DS2VASc and HASBLED
Tachyarrhythmia + adverse features action
D/C shock x3 –> Amiodarone 300mg –> Repeat shock –> Amiodarone 900mg over 24h
Treatment of Hypertension
- <55y= ACEi/ ARB >55y or Afro-Caribbean= CCB eg amlodipine (hydralazine for Afro-Caribbean)
- ACEi + CCB
- ACEi + CCB + Thiazide diuretic
- ACEi + CCB + Thiazide diuretic + Increase dose of diuretic/ switch diuretic, or add beta blocker
Management of angina pectoris
- Stop CVS RF
- 75mg aspirin
- PRN GTN (2x –> ambulance)
- Antianginals: beta blocker/ CCB –> isosorbide mononitrate
- Revascularisation
Causes, features, Ix, Tx of cardiac tamponade
- Causes- trauma, lung/ breast Ca, MI, pericarditis
- Signs:
- Pulsus paradoxus
- Beck’s triad- falling BP, rising JVP, muffled HS
- Raised JVP on inspiration
- Ix:
- ECG- electrical alternans
- CXR- globular heart
- ECHO diagnostic
- Tx: pericardiocentesis ASAP!