cardiovascular Flashcards
Functions of the blood
- Transport of gases, nutrients, and waste products.
- Transport of processed molecules
- Transport of regulatory molecules
- Transport of pH and osmosis
- Maintenance of body temperature
- Protection against foreign substances
- Clot formation
What is Plasma?
a yellow fluid that consists of 91% water, 7% proteins, and 2% other components
Albumin
58% in the plasma proteins. The osmotic pressure of blood
Globulins
38% of plasma proteins. Part of the immune system and some are clotting factors
Fibrinogen
Clotting factors that constitutes of 4% plasma proteins
Serum
is a plasma without clotting factor
RBC or erythrocytes
95% of the volume of the formed elements
WBC or leukocytes
5% of the volume of the formed elements. Larger than RBC. Lack of hemoglobin
hematopoiesis
process of blood cell production
All formed elements of blood are derived from a single population of cells
Stem cells or hemocytoblasts
responsible for the cells red color
hemoglobin
Functions of RBC
- transport of oxygen from the lungs to the various tissues of the body
- transport of carbon dioxide from the tissues to the lungs
Give rise to the RBC line
proerythroblasts
Low blood oxygen levels stimulate red blood cell production by increasing the formation and release of the glycoprotein
Erythropoietin
Yellow pigment molecule. Normally taken up by thr liver and released into small intestine
bilirubin
WBC and platelets make up _. A thin white layer of cells between plasma and RBC
buffy coat
WBC can leave the blood and travel by
ameboid movemenet
2 functions of WBC
- protect the body against invading microorganisms and other pathogens
- to remove dead cells and debris from the tissues by phagocytosis
Containing large cytoplasmic granules
Granulocytes
Very small granules that cannot be seen easily
agranulocytes
3 kinds of granulocytes
- neutrophils - most common type of WBC, have small cytoplasmic granules that stain with both acidic and basic dyes.
- basophils - least common of WBC, have large cytoplasmic granules that stain blue. Promote inflammation, prevents the formation of clots.
- eosinophils - cytoplasmic granules ghat stain bright red. Involved in inflammatory responses associated with allergies and asthma.
2 of agranulocytes
- Lymphocytes - smallest of WBC. Body immune response. Production of anti bodies that destroy microoorganisms
- Monocytes- largest of WBC.
Phagocytize bacteria, dead cells, cell fragments, and any other debris within the tissues
Macrophages
Minute fragmemts of cells
Platelets
Large cells
megakaryocytes
immediate but temporary constriction of blood vessel that results when smooth muscle within the wall of vessel contracts
Vascular spasm
Accumulation of platelets that can seal up a small break in a blood vessel
Platelet plug
Platelets stick to the collagen exposed by blood vessel damage
platelet adhesion
Protein produced and secreted by blood vessel endothelial cells
Von Willebrand factor
As platelets become activated, they express surface receptor
Fibrinogen receptors
Fibrinogen forms bridges between the fibrinogen receptors of numerous platelets, resulting in a platelet plug
Platelet aggregation
When a blood vessel is severely damaged, results in the formation of a clot
Blood clotting or coagulation
network of thread like protein fibers
clot
traps blood cells, platelets, and fluid
fibrin
Formation of blood clot depends on a number of proteins within plasma
Clotting factors
analysis of blood that provides much useful information.
CBC
Red Blood Count for male and female
Male - 4.6 - 6.2 million RBC per microliter of blood
Female - 4.2 - 5.4 million RBC per microliter of blood
overabundance of RBC
erythrocytosis
Hemoglobin measurement for male and female
male - 14-18g per 100mL of blood
female - 12-16g per 100 mL of blood
abnormally low hemoglobin measurement. Reduced number of RBC
anemia
percentage of the total blood volume that is composed of RBC
hematocrit
The blood’s ability to clot can be assessed by the platelet count and the prothrombin time measurement
Clotting
Platelet count
250,000 - 400,000 platelets per microliter of blood
platelet count is greatly reduced
thrombocytopenia