Cardiovascular Flashcards
what’s the 2 types of thoracic aortic aneurysms? which one is more common?
ascending (more common) and descending
what’s the MCC of ascending aortic aneurysm?
cystic medial necrosis
what’s the MCC of descending aortic aneurysm?
atherosclerosis
what are the s/s of thoracic aortic aneurysm?
commonly asx
Chest, back, flank, abdominal pain: compression or distortion of local anatomy
Cold foot: thromboembolism preventing blood flow to area
what’s the PE of thoracic aortic aneurysms?
commonly normal
if rupture -> hemorrhagic shock (tachy and decreased. BP)
what’s the best imaging study for dx of thoracic aortic aneurysm?
CT angiogram
what will you see on CXR if it’s a thoracic aortic aneurysm?
wide mediastinum (only if aneurysm is large enough)
what type of thoracic aortic aneurysm can ECHO (TTE) dx?
proximal ascending aorta
when do you use MRI for dx of thoracic aortic aneurysm?
if pt can’t get IV contrast for CTA
what’s the tx for thoracic aortic aneurysm?
Beta blockers(especially for pts w/ Marfan)
ACEIs/ARBs
(limit expansion and r/o rupture)
Endovascular repair→ catheter guided stent graft placed
-Closed procedure (preferred)
when do you do surgical repair or placement of prosthetic graft for thoracic aortic aneurysm?
Symptomatic
Ascending aneurysm >5.5 cm
Descending aneurysm >6.5 cm
where does abdominal aortic aneurysm MC occur?
infrarenally - at level of renal arteries
at what size is part of the abdominal aorta considered an aneurysm?
> 3.0 cm
what is the MC RF for development of AAA? what’s a major RF?
atherosclerosis = MC RF
smoking = major RF
what are the RFs for development of AAA?
***Atherosclerosis = MC RF
***Age >60 y/o
***Smoking: major RF - promotes rate of aneurysm formation, growth and rupture
Male, Caucasians
Hyperlipidemia, ***connective tissue d/o (Marfan’s syndrome), Syphilis, HTN
what’s the s/s of AAA?
Most are asx until they rupture
(often incidental finding on US, CT, MRI)
Acute leakage/rupture
Classic presentation: older male (>60 y/o) with:
- Severe back or abdominal pain who presents with syncope or hypotension & tender, pulsatile abd mass
- +/- Cullen’s sign (flank ecchymosis)
what’s the classic presentation of AAA?
older male (>60 y/o) with: -Severe back or abdominal pain who presents with syncope or hypotension & tender, pulsatile abd mass
- +/- Cullen’s sign (flank ecchymosis)
at what size of AAA is there an increased rupture risk?
> 5cm
how and who do you screen for AAA?
Abd U/S indicated for:
- Men 65-74 y/o with h/o smoking
- Sibling or offspring of persons w/ AAA
- Pts w/ thoracic aortic or peripheral arterial aneurysms
- Pts w/ connective tissue d/o’s → Marfan’s and Ehlers-Danlos
how do you dx AAA?
Abd U/S → best imaging study
-Alternatively: CT or MRI
Angiography = gold standard
what’s the BEST imaging study for AAA?
Abd U/S
what’s the GOLD STANDARD imaging study for AAA?
angiography
what’s the definitive tx of AAA?
surgical repair
what’s the tx for AAA 3-4 cm?
monitor by U/S every year
what’s the tx for AAA 4-4.5 cm?
monitor by U/S every 6 months
what’s the tx for AAA >4.5 cm?
vascular surgeon referral
what’s the tx for AAA >/= 5.5 cm OR >0/5 cm expansion in 6 months?
IMMEDIATE SURGICAL REPAIR (even if asx), symptomatic pts or pts w/ acute rupture
what’s the tx after endovascular repair of AAA?
long-term surveillance w/ CTA or MRA
what’s an aortic dissection?
tear in the innermost layer of aorta (intima) -> creates false lumen (channel)
what’s the MC place to have an aortic dissection?
ascending aorta (high mortality)
what’s the MOST IMPT. predisposing factor of aortic dissection?
HTN
what’s the s/s of aortic dissection?
Chest Pain: MC; sudden onset of severe, tearing (ripping, knife-like)* chest/upper back pain*
-a/w N/V, diaphoresis
Decr. peripheral pulses
-Variation in pulse (>20mmHg difference b/w the right and left arm)***
what sx is MC in distal ascending aortic dissection?
HTN
what sx occurs in a ascending dissections?
acute new-onset aortic regurgitation
what’s the BEST imaging study for aortic dissection? what’s the GOLD STANDARD?
CTA = best imaging study
MRI angiography = gold standard
what do you see on CXR for aortic dissection?
WIDENING OF THE MEDIASTINUM
what’s the initial tx for aortic dissection?
HR and BP control w/ Esmolol
Pain relief w/ morphine
what’s the tx for acute dissection of ascending aorta?
surgical emergency!!!
what’s the tx for acute dissection of descending aorta?
Treat medically first
Surgery → progression w/ organ ischemia or continued hemorrhage into pleural or retroperitoneal space
what’s the long-term management for aortic dissection?
Medical therapy: minimize aortic wall stress (lifelong BB and maintaining goal BP <120/80)
Serial imaging: 3mo → 6mo → 12mo
q1-2 yrs thereafter