Cardiovascular Flashcards
An ECG showing an irregularly irregular heart rate and absent p waves are characteristic signs of which ECG pattern?
Atrial Fibrillation
This is when the left atrium loses refractoriness before the end of atrial systole, causing recurrent, uncoordinated contraction
What classification system is used to classify severity of cardiovascular disability in heart failure
The New York Heart Association (NYHA) Classification system
ECG features of First Degree Heart Block
Prolonged PR interval (>200ms)
How is first degree heart block managed
It is a benign condition and does not need treating. However, any pathological underlying cause should be reversed.
What inheritance pattern is Hypertrophic obstructive cardiomyopathy
Autosomal dominant
Hypertrophic obstructive cardiomyopathy are at an increased risk of which conditions
Heart failure
Myocardial infarction
Arrhythmias
Sudden cardiac death
ECG features of Complete Heart Block
No relationship between the P waves and the QRS complexes.
This occurs when the electrical impulses do not pass successfully from the atria to the ventricles
ECG features of Second degree type 2 heart block
Fixed prolonged PR interval with intermittently absent QRS complexes following a P wave
ECG features of Second degree type 1 heart block
Gradual lengthening PR interval which eventually leads to an absent QRS complex
Also known as Wenkebach
Characteristic CXR feature of granulomatosis with polyangiitis
Bilateral nodular and cavitating infiltrates
What three body systems are typically affected in Granulomatosis with polyangiitis (Wegener’s granulomatosis)
Upper respiratory tract e.g. Epistaxis, chronic sinusitis
Lower respiratory tract e.g. Cough, haemoptysis
Renal e.g. Haematuria
A high NT-proBNP is suggestive of what condition
A high NT-proBNP suggests ventricular stretch and a likely diagnosis of congestive cardiac failure and pulmonary oedema
What is the gold standard investigation to confirm the definitive diagnosis of heart failure
Echocardiogram (ECHO)
What is the ECG pattern:
Broad complex tachycardia without P-waves
Ventricular tachycardia (VT)
What is the ECG features of P pulmonale?
Right atrial enlargement produces a peaked P wave (P pulmonale)
Sign of cor pulmonale i.e. right heart failure secondary to long-standing pulmonary arterial hypertension
Tall, peaked T waves, QTc shortening and ST-segment depression on ECG is characteristic of which electrolyte disturbance
Hyperkalaemia
T wave inversion, QTc prolongation and visible U waves on ECG is characteristic of which electrolyte disturbance
Hypokalaemia
Isolated QTc shortening on ECG is characteristic of which electrolyte disturbance
Hypercalcaemia
Isolated QTc elongation on ECG is characteristic of which electrolyte disturbance
Hypocalcaemia
None
None
Short PR intervals and delta waves (slurred upstroke in the QRS complex) is the classical ECG pattern of what condition?
Wolff-Parkinson-White syndrome (a type of supraventricular tachycardia)
How is Wolff-Parkinson-White syndrome managed?
Ablation of the accessory pathway
ECG finding in hypothermia
Jesus its bloody freezing = J waves, irregular rhythms, bradycardia, first degree heart block
J-wave/Osborne wave are positive deflection is seen occurring at the junction between the QRS complex and the ST-segment.
P pulmonale is an ECG finding of what condition
Right atrial enlargement
P pulmonale refers to peaked P wave i.e. P waves have a large amplitude
ECG findings of pericarditis
Widespread saddle-shaped ST elevation
PR depression
Likely Dx:
Pleuritic chest pain that radiates to the back
Pain relieved by sitting up
Pain worse on lying flat
Recent Hx of viral infection
Pericarditis (inflammation of the pericardium)
What is the definitive treatment for cardiac tamponade
Pericardiocentesis i.e. insertion of a needle into the pericardium to drain the built up fluid
Atropine is not working for acute bradycardia with haemodynamically unstable features secondary to beta blocker overdose
What is the next best step
Glucagon
What is the first line management in acute pericarditis
Exercise restriction and NSAIDs
Gold standard investigation to diagnose aortic dissection
CT angiogram
A false lumen is a key finding in diagnostic of aortic dissection
What is the initial management of aortic dissection
Dissection occurs when a tear in the tunica intima of the aorta creates a false lumen whereby blood can flow between the inner and outer layers of the walls of the aorta.
First line is ABCDE with resuscitation if required
Control the blood pressure to prevent further extension of the dissection with IV beta blocker, most commonly IV metoprolol
Radio-radial delay and radio-femoral delay are clinical signs of what condition
Aortic dissection
What affect does Clarithromycin have on ECG
Prolongs the QTc interval
What is the normal QT interval
< 440ms (two large squares)
When is the QT interval considered prolonged
> 450 ms (two large squares)
A collapsing pulse is pathognomonic feature of what condition
Aortic regurgitation
Name the murmur
Early diastolic murmur which is heard best over the left sternal edge
Aortic regurgitation
Malar flush is a feature of what type of murmur?
Mitral stenosis
Malar = Mitral
Wide pulse pressure is associated with what type of murmur?
Aortic regurgitation i.e. the systolic and the diastolic are wide apart such as 157/61 mmHg
The pulse is wide so you have to Reach for it (Reach = Regurgiation)
Narrow pulse pressure is associated with what type of murmur?
Aortic stenosis i.e. the systolic and the diastolic are close together
Narrow valve flaps in stenosis= narrow pulse pressure
What is the first line imaging investigation for infective endocarditis
Transthoracic echocardiogram
Although not the first line imaging investigation for infective endocarditis. Which test is the most sensitive diagnostic test
Transoesophageal echocardiogram
What is the name of the criteria used as a diagnostic guide for infective endocarditis (IE), but should be used together with clinical judgement.
Modified Duke criteria
Definite IE :-
Two major criteria
OR
One major + three minor criteria
OR
All five minor criteria
Why is prolonged PR interval on ECG, with evidence of aortic valve involvement on echocardiogram an indication for surgery in infective endocarditis
This finding is highly associated with an aortic root abscess, a potentially fatal complication of infective endocarditis
An aortic root abscess requires prompt and extensive surgical debridement of infected and necrotic tissue, with subsequent prosthetic valve reconstruction.
What type of heart block is this?
ECG finding: PR interval >200ms
First degree heart block
Caused the prolonged conduction of electrical activity through the AV node
Name a cause of first degree heart block
High vagal tone (e.g. athletes)
MI (mainly inferior)
Electrolyte abnormalities (e.g. hyperkalaemia)
Drugs: NHP-CCBs, beta-blockers, digoxin, cholinesterase inhibitors
How is first degree heart block managed
First degree heart block itself is benign and does not need treating. However, any pathological underlying cause should be reversed.
What type of heart block is this?
Progressive lengthening of the PR interval until the P wave drop beat occurs
2nd Degree heart block - Mobitz type I
Usually due to reversible conduction block at the AV node
Usually a pattern such as 2:1
Name a cause of 2nd Degree heart block - Mobitz type I
High vagal tone (e.g. athletes)
MI (mainly inferior)
Myocarditis
Cardiac surgery
Drugs such as beta/calcium channel blockers, digoxin
Management of 2nd degree heart block Mobitz Type I
Generally asymptomatic and does not require any specific management as the risk of high AV block/ complete heart block is low.
If symptoms do arise, ECG monitoring may be required, exclude precipitating drugs and if bradycardic may require atropine.
What type of heart block is this?
Random P wave block (no pattern)
Constant PR intervals and then randomly a block occurs
Second degree heart block Mobitz type II
Usually caused by conduction system failure, especially at the His-Purkinje system
Different to Mobitz type I as type I has a prolonging PR interval before a drop beat and usually a pattern e.g. 3:1 block.
Name a cause of second degree heart block Mobitz Type II
Infarction particularly anterior MI which damages the bundle branches
Surgery: mitral valve repair or septal ablation
Inflammatory/autoimmune: rheumatic heart disease, SLE, systemic sclerosis, myocarditis
Fibrosis: Lenegre’s disease
Infiltration: sarcoidosis, haemochromatosis, amyloidosis
Medication: beta-blockers, calcium channel blockers, Digoxin, amiodarone
What is the definitive management of second degree heart block mobitz type II
Second-degree requires Secondary input
Permanent pacemaker as these patients are at risk of risk of complete heart block and becoming haemodynamically unstable
What heart block is this?
Severe bradycardia and dissociation between the P waves and the QRS complexes.
Third degree heart block
Name a cause of Third Degree Heart Block
MI (mainly inferior)
Drugs acting at the AV node (beta blockers, calcium channel blockers)
Idiopathic fibrosis
What is the definitive management of Third Degree Heart Block
Permanent pacemaker due to the risk of sudden death
Delta waves is an ECG finding of what condition
Delta waves are intermittent QRS complexes with pre-excitation
Wolff-Parkinson-White syndrome
What is the definitive management of Wolff-Parkinson-White syndrome
Catheter ablation of the accessory conduction pathway
What is the management of Wolff-Parkinson-White syndrome in unstable patients
Urgent direct current (DC) cardioversion
Unstable patients (blood pressure <90/60mmHg or with signs of systemic hypoperfusion or fast atrial fibrillation)
What is the first line management option for Wolff-Parkinson-White syndrome in a stable patient
Vagal manoeuvres (carotid sinus massage or Valsalva manoeuvre)
Vagal manoeuvres (carotid sinus massage or Valsalva manoeuvre) is the first line management option for Wolff-Parkinson-White syndrome in a stable patient.
If that fails what is second line?
IV adenosine
De Musset’s sign is when there is a rhythmic head nodding or bobbing in-sync with each heart beat.
Which type of murmur is this associated with?
Aortic regurgitation
What criteria is used to classic findings to aid the diagnosis of Rheumatic Fever
Jones criteria
Classifies the findings into major and minor manifestations
What drug may be used fourth-line in hypertensive patients who have a potassium greater than 4.5 mmol/L
Beta blocker e.g. Propranolol
What drug may be used fourth-line in hypertensive patients who have a potassium less than 4.5 mmol/L
Mineralocorticoid receptor antagonists e.g. Spironolactone as it is potassium-sparing, which means it can increase potassium levels
First-line treatment for hypertension in patients of any age with a history of type 2 diabetes
ACE-inhibitor e.g. Ramipril
If unable to tolerate ACE-inhibitor then switch to Angiotensin Receptor Blocker e.g. Candesartan
First-line treatment for hypertension in patients over 55 years of age with no history of type 2 diabetes
Calcium channel blocker e.g. Amlodipine