Cardiomyopathy Flashcards

1
Q

cardiomyopathy definition:

A

-a group of diseases of varying etiologies in which the main featuer is myocardial involvement

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2
Q

dilated cardiomyopathy definition:

A
  • a disorder of myocardial muscle resulting in dilation and weakening of the left ventricle
  • bad systole!
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3
Q

hypertrophic cardiomyopathy definition:

A
  • disorders of myocardial muscle resulting in hypertrophy, left ventricular dysfunction and arrhythmias
  • usually familial
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4
Q

restrictive cardiomyopathy definition:

A

a group of disorders resulting in excessive myocardial stiffening with resultant ventricular dysfunction

-cant fill very well - bad diastole

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5
Q

Most common cause of cardiomyopathy in western hemisphere?

A

-chagas disease - VIRAL

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6
Q

Functional classifications:

A

1) dilated-ventricular dilation and contractile dysfunction
- MOST COMMON
2) hypertrophic-thickened walls (symmetric or asymmetric) with preserved contractile function
- FAMILIAL
3) restrictive-impaired diastolic filling without dilation

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7
Q

Dilated cardiomyopathy

-etiologies

A

most common to least:

  • idiopathic
  • ischemic
  • HTN
  • alcohol
  • infectious (chagas viral)
  • metabolic (beriberi, kwashiorkor, thyroid dis, DM)
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8
Q

Dilated cardiomyopathy - history:

A
  • angina or previous MI
  • systemic arterial HTN
  • alcohol or other toxins
  • foreign travel/residence
  • other diagnoses - DM
  • signs/symptoms of HF (LV, RV or both)
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9
Q

symptoms of LV failure:

A

1) fatigue
2) weakness
3) dyspnea
- exertional
- orthopnea (venous return inc when laying = more blood everywhere including lungs = need to sit up bc not gettign good V/Q)
- PND (after youve been asleep)
4) pallor, tachycardia

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10
Q

Signs of LV failre:

A
  • pale, often dyspneic
  • vital signs cary - tachycardia often
  • cardiac apex displaced left and down
  • apical lift and/or thrill
  • S1 and S2 normal
  • P2 varies
  • S3 always present - VOLUME OVERLOADED LV
  • many different murmurs (MR, AS)
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11
Q

symptoms of RV failure

A
  • same as LV but dyspnea improves as RV fails (lungs clear up a little)
  • anorexia
  • early satiety & abdominal fullness (congestion)
  • pallor, tachycardia
  • elevated jugular venous pulsations (no valves!)
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12
Q

most common cause of RV failure?

A

LV failure!

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13
Q

signs of RV failure:

A
  • jugular venous pulses elevated
  • cardiomegaly, RV lift
  • P2 varies
  • RV and LV S3 universal
  • various murmurs
  • pulsus alternans (weak heart- and each beat some muscle fibers cant recover but next cycle they can so the R wave gets bigger and smaller)
  • hepatomeg/splenomeg
  • ascites
  • peripheral edema
  • evidence of poor nutrition (muscle wasting)
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14
Q

Dilated cardiomyopathy - imaging:

A
  • chest x-ray = big heart
  • echocardiogram
  • radionuclide studies
  • cardiac catheterization
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15
Q

Dilated cardiomyopathy-cardiac catherterization

A

1) Hemodynamics
- inc LV end diastolic pressure (LVEDP)
- inc PA, and RV pressures
- dec LV ejection fraction (LVEF)
2) left ventriculogram
- abnormal dilation
- wall motion reduced
3) coronary arteries

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16
Q

common consequence of chronic alcoholism?

A

-atrial fib!

17
Q

Alcoholic cardiomyopathy - tx?

A

-tx like other + thiamine

pt must stop drinking!! or DEAD within 3 years

18
Q

Alcoholic cardiomyopathy - common reasons for death?

A

v-fib or pump failure

19
Q

Hypertrophic cardiomyopathy

-terminology:

A

1) IHSS - idiopathic hypertrophic subaortic stenosis
2) HOCM - hypertrophic obstructive cardiomyopathy
- hypertrophic, obstructive
- equivalent to IHSS
3) HCM - hypertrophic cardiomyopathy
- hypertrophic, obstructive
- hypertrophic, non-obstructive (most)
- best terminology

20
Q

pathology of hypertrophic cardiomyopathy:

A

1) macroscopic:
- inc myocardial mass
- asymmetric septal hypertrophy
- concentric hypertrophy
- apical hypertrophy
2) microscopic
- myofibrillary dysarray - whorls of deformed myocytes
- prominent fibrosis
- abnormal intramural coronaries

21
Q

Hypertrophic cardiomyopathy

-clinical manifestations:

A

1) symptoms
- young onset (age 26)
- sudden death
- dyspnea
- angina pectoris
- fatigue
2) signs
- slight displaced, bifid LV impulse
- bisferiens carotid pulse
- S4 very common-stiff ventricle
- systolic murmur of variable qualities

22
Q

Hypertrophic cardiomyopathy

-ECG?

A
  • inc voltages in anterior leads
  • ST and T wave changes (repol abnormality)
  • Q-waves (usually inferior, lateral)
23
Q

Diagnostic for Hypertrophic cardiomyopathy

A

-echocardiogram!

24
Q

Tx for hypertrophic cardiomyopathy?

A
  • reduce physical activty
  • Drugs: - beta blockers (reduce contractility)
  • myotomy/myectomy - carve out a piece of the septum
25
Q

restrictive cardiomyopathy -what is the hallmark?

A

diastolic dysfunction

26
Q

issue with restrictive cardiomyopathy?

A
  • amyloid in the heart muscle walls
  • heart gets too stiff
  • heart cant fill/pump properly

==> you die!