Cardiology Qs Flashcards
What drugs can cause torsades de pointes
Macrolides [-mycin] e.g. azithromycin/ erythromycin
Antiarrhythmics e.g. amiadarone, sotalol
Tricylic antidepressants
Which drugs is contraindicated in a patient with ventricular tachycardia
Verapamil
What arrythmia can a subarachnoid haemorrhage cause?
Bleed = tosardes de pointes *polymorphic ventricular tachycardia
Why can heart block occur following and MI?
basc in a STEMI you can get heart block features. such as LBBB. But also in the occlusion of the RCA so the inferior leads are affected, the AV node has become ischaemic = block
What is the preferred route of access for a primary PCI?
Radial access
Usually Prasugrel is given when arranging for an urgent PCI for MI, when is clopidogrel given instead?
If the patient is already taking an oral anticoagulant e.g. apixiban, give clopidogrel
Complication of post MI:
- weeks after MI
- persistent ST elevation
- Bibasal crackles
- 3rd + 4th heart sound
Left ventricular aneurysm
Complication of post MI:
- within 48 hours
- chest pain
- Muffled heart sounds
Left ventricular free wall rupture
What is special about a posterior STEMI on ECG?
Will only be depression noted on V1-V3
this is because on a 12 lead elevation will not be noticible
When is angioplasty with stenting done for limb ischaemia?
if the stenosis in leg is focal or limited to a small area e.g. a thrombus
When is open bypass graft done for a patient with limb ischaemia?
if the vascular block is long or multifocal, best revascularisation option is open bypass graft
CXR should be done for PE, when?
CTPA is crutial to do after WELLs score, do CXR prior to this to rule out other pathologies
Can a CTPA for a PE be done without contrast
no cause u wont see nothing so its not diagnostic, if someone is allergic to contrast cannot do this at all, so give DOAC whilst waiting for next best option which is V/Q scan
when to stop the pill before surgery to reduce PE risk?
4 weeks
Common organism if infective endocarditis is <2 months post valve surgery?
staphylococcus epidermidis
infective endocarditis organism - hx with dental procedure/poor hygiene
streptococcus viridans
infective endocarditis organism linked with colorectal cancer?
streptococcus bovis
ARCC risk factors for aortic stenosis
A - advanced age
R - rheumatic fever
C - congenital bicuspid
C - chronic kidney disease
SADDD aortic stenosis sx
exertion syncope
angina
exertion dyspnoea
dizzy
decreased exercise tolerance
SADDD aortic stenosis sx
exertion syncope
angina
exertion dyspnoea
dizzy
decreased exercise tolerance
BPM for atrial fib
300-600bpm
Most common cause for Afib?
Ischaemic heart disease
( risk factor - advancing age )
pulmonary sign for ventricular tachy?
Bibasal crackles (oedema)
drug causes for Vtach?
Amiadarone
tricyclic antidepressant
erythromycin
ECG for Brugada?
Massive convex ST elevation followed by a negative T wave
elevated is 2mm+ and seen in 1+ Leads from V1-V3
most important cause of Vtach clinically
hypoK then hypoM
gut stroke?
gut angina?
colicky abdo pain + diarrhoea + fever but also rectal bleed?
gut stroke - good way to recall acute mesenteric ischaemia
gut angina - describes chronic mesenteric ischaemia well
rectal bleed alongside these hypoperfusion symptoms = ischaemic colitis
investigation for a pregnant women with PE and a wells score of 4+?
A wells score of 4+ = CT pul angiogram BUT cannot do this in pregnant ( or renal impairment or contrast allergy)
Do V/Q scan
gas gangrene organism
clostidium perfringes
wet vs dry gangrene management
wet - surgical debridement + broad spec abx
dry - IV heparin + surgical revasc, consider amputation is non viable
aortic aneurysm screening imaging?
aortic aneurysms rupture imaging?
stable px aortic dissection imaging ?
unstable px aortic dissection imaging?
aortic aneurysm screening imaging?
- USS (male 65+)
aortic aneurysms rupture imaging?
- CT angio
stable px aortic dissection imaging ?
- CT angio
unstable px aortic dissection imaging?
- Echo
if acute heart failure is not responding to tx (oxygen, furosemide?
CPAP
myocarditis summary?
Usually viral hx (flu like illness) in a younger patient
Coxsackie virus is key
acute chest pain
pulmonary oedema
bilateral infiltrates on CXR
ECG may show ST elevation + troponin etc elevated
Pericardial disease summary
Acute 4-6 weeks (coxsackie virus)
Chronic 3+ months –> leads to constrictive pericarditis (elevated JVP, positive kussmaul’s, heart failure)
cardiac tamponade –> worst, Becks triad of raised JVP, decrease BP, muffled heart sounds, pulsus paradox
A while after MI - autoimmune drusslers
Kidney failure - uraemic pericarditis
Signs = chest pain better on leaning forward, pericardial rub, signs of heart failure if bad
triad haemochromatosis?
Arthralgia
erectile dysfunction
fatigue
+
tanning/bronze skin
Aortic stenosis sounds (mumurs, radiation, heart sounds, pulse signs)
Ejection systolic murmur
radiates to carotids
Soft S2 sound
Slow rising carotid pulse
Narrow pulse pressure
Mitral stenosis sounds, murmurs, radiation, other signs?
Distolic mumur, low pitch rumble
radiates to apex
palpable apex beat - S1
malar flush
mitral regurgitation murmur, radiation, sounds
pansystolic murmur, heard as ‘blowing’
into th axilla
quiet S1 due to valve closure issue
Mitral regurgitation ECG?
P mitrale (broad notched P wave due to atrial enlargement)
Aortic regurgitation mumur, accentuation, pulse signs, other signs
early diastolic murmur, high pitched
px leaned forward over aortic area
widened pulse pressure + collapsing pulse
- traube’s sign pistol shot bruit femoral artery
- muller’s sign - pulsation uvula
- quinke’s sign - pulsation of the nailbeds
- de musset sign - head bopping
STEMI mx
Aspirin 300mg
PCI possible in 2 hours?
Yes = do it and give prusugrel (clopi if already on anticoag)
No = Thrombolysis with alteplase + antithrombin
Unstable angina/NSTEMI mx?
Aspirin 300mg + fondaparinux *
Calculate GRACE score
<3%: aspirin + ticagrelor (or clopi if risk)
> 3%: angiography with PCI in 72 hrs, again give aspirin + ticagrelor
- do not give fondaparinux in a very high bleeding risk or if PCI is to happen immediately, in that cayse give aspirin + unfractionated heparin ( can reverse easily with protamine sulfate)
Long term mx ACS (secondary prevention post MI)
Dual antiplatelet therapy, ACEi, Beta blocker, stain 80g