Cardiology Pharmacotherapeutics

Question 1

What is the BP target for people with hypertension?

Answer 1

130/85

Question 2

1 blood pressure medication typical confers ___ mmHg of BP reduction

Answer 2

20/10

Question 3

What is the dosing regimen of amlodipine and nifedipine LA for HTN?

Answer 3

Amlodipine: Initiate 5mg OD, evaluate after 2-4 weeks, titrate to max dose of 10mg OD

Nifedipine LA: Initiate 30-60mg OD, evaluate after 2-4 weeks, titrate to max dose of 90mg OD

Question 4

What is the dosing regimen for lisinopril and enalapril for HTN?

Answer 4

Lisinopril: Initiate 5-10mg OD, evaluate after 2-4 weeks, titrate to max dose of 40mg OD

Enalapril: Initiate 5-10mg OD, evaluate after 2-4 weeks, titrate to max dose of 40mg OD

Question 5

What is the dosing regimen of valsartan, losartan, and telmisartan?

Answer 5

Valsartan: Initiate 80-160mg OD, evaluate after 2-4 weeks, titrate to max dose of 320mg OD

Losartan: Initiate 25-50mg OD, evaluate after 2-4 weeks, titrate to max dose of 100mg OD

Telmisartan: Initiate 20-40mg OD, evaluate after 2-4 weeks, titrate to max dose of 80mg OD

Question 6

What is the dosing regimen for hydrochlorothiazide for HTN?

Answer 6

Initiate 12.5 - 25mg OD, evaluate after 2-4 weeks, titrate to max dose of 50mg OD

Question 7

For elderly >80yo, treatment should only be started when SBP _________

Answer 7

persistently >160

Question 8

When should blood pressure treatment be offered (for most adults)?

Answer 8

when BP >140
if lower, offer non-pharm –> assess in 3 months

Question 9

What are the monitoring parameters for ACEi / ARBs?

Answer 9

Renal panel (potassium, SCr), angioedema, BP, cough

Question 10

What are the monitoring parameters for CCB?

Answer 10

peripheral edema, pulse rate (esp for NDHP)

Question 11

What are the monitoring parameters for diuretics?