Cardiology Flashcards
Opening
Snap - MS
Click - MVP
Closure
S1
S2
Loud S1
MS
Short PR (WPW)
Tachycardia
Thyrotoxicosis
Soft S1
MR
Long PR
inc’d LVEDP
S2 inspiration
A2 - AV closess first
P2 - PV closes last -> physiologist split
S2 expiration
both valves close at same time
S2 split inc’d
closese earlier - MR, VSD
Closes later PS, pulm HTN (loud P2) RBBB
Fixed S2 split
ASD
paradoxical S2 split
AS, HTN, LBBB
S3
inc'd flow chronic MR CHF TR, PDA BENIGN IN KIDS pregnancy
Inspiration
MORE BLOOD IN R HEART
S4
Decreased compliance Acute MR HOCM LVH AS Ischemia
Pericardial friction rub
Superficial scratch sound best heard when pt upright leaning forward and deep breath in pericarditis
Pericardial knock
constrictive pericarditis - sharp early diastolic sound (early 3rd sound)
Physioligc during expiration
Single S2
HTN/AS/LBBB
Paradoxical S2 split
ASD
Fixed split
Calcified AS
Single S2 (soft A2)
HTN
Loud A2
Pulm HTN
Loud P2
Physiologist split
A2 before P2
Pulsus tardus
slowly rising pulse
AS
Pulsus bisferients
rapid upstroke - bifid/trifid
HCM
Pulsus alternans
one heart snd normal, one abn severe HF cardiac tamponade SVC obstruction Pulm obstruction
Hyperkinetic
High output state
PDA
Thyrotoxicosis
Hypokinetic
Low output states
Kusmal
deep breath more blood into R heart - taemponade - R septum bulges into LV, dec’d BP on inspiration, JVP bulges
Auscultation
R IInd IC space (Aortic Area)
AS
AI
Left II IC Space (Pulm area)
PS, PR, AI, PDA
LLSB (Tricuspid area)
TS, TR
ASD, VSD
HOCM
Apex (Mitral Area)
MS
MR
AR
Palpation
Left parasternal area
Hyperdynamic implse (inc’d RV volume (ASD or TR)
Sustained L parasternal heave - RVH, (MS, pHTN, PS)
Apical area Hyperdynamic impulse Inc'd LV vol (Hyprthyroid, Anemia, preimary MR, AR with nl EF, PDA VSD) Susptained Apex lift/impulse LVH (HTN, Dil CM) IHD, AR with low EF Bifid/trifid apical impulse - HOCM
AV Valve Holosystolic murmur
MR, MR, VSD
V valves Mid systolic murmur
AS, PS
AV Valves Late systolic murmur
MVP - mid systolic click
Diastolic mumur
All in-flow to ventricles creates diastolic murmurs
AV valves Mid diastolic murmur
MS, TS
AV valve - late diastolic murmur, mid systolic plop
Arial Myxoma - > surgery
V valves Early diastolic murmur
AR, PR
Continuous murmur
PDA
Pt with fixed split 2nd heart sound and mid systolic -diastolic rumble dx?
ASD
Inspiration
inc’d flow to R side of heart, all R sided murmurs increase
Expiration
Inc’d flow to L side of heart - all L sided murmurs increase
Inc’d flow INCREASES all murmurs EXCEPT
HOCM/MVP (decrease)
Inc’d flow
Sitting, squatting, leg raising
Dec’d flow
Standing, Valsalva
Handgrip
increases afterload, increases flow to murmurs that flow backward (AI, MR, VSD)
What happens to murmur during handgrip or phenylephrine
Handgrip inc’d afterload, LV cavit size inc’s so ALL murmurs increase including MR
Except: dec’s HOCM, MVP, AS
What happens to murmurs with amyl nitrate use
Decreaes afterload, so its easy for blood to be pushed into systemic cir, LV cavity decreased MR dec's MVP inc's HOCM inc's AS inc's
What happens to murmur post PVC
PVC=inc’d volume, dec’d afterload
HOCM/AS increase
MVP dec’s
What happens to blood that returns to heart during valsalva maneuver
Increases intrathoracic pressure and DEcreases blood return to heart
Kussmaul’s sign
Neck vins DISTENTION on INSPIRATION
constrictive pericarditis
cardiac tamoponade
RV infarct
Application of pressure in the RUQ causes engorged Right jugular vein - rapidly improved upon release of pressure - indicates…
Increased jugular venous pressure
inspiration
inc’d R side murmurs
Dec’d L side murmurs
Expiration
inc’d L side murmurs
Dec’s R sided murmurs
Standing/valsalva
Inc’d HOCM, MVP
Dec’d all other murmurs
Squatting/Sitting
Dec’d HOCM, MVP
Inc’d All other murmurs
Hand grip
Dec’d HOCM, AS, MVP
Inc’d MR, MVP
Post PVC
Inc’d HOCM, AS
Dec’d MVP
AS
inc’d standing, valsalva, post-PVC
dec’d with handgrip
MR
inc’d standing, valsalva
Dec’d Post=PVC, handgrip
MVP
Dec’d standing, valsalva, post-PVC
Inc’d with handgrip
HOCM
Dec’d Standing, valsalva, handgrip
Inc’d Post-PVC
16yo pw routine checkup - PE reveals a murmur at LSB radiating thru pre-cordium - no change with valsalva or respiration - exam LVH dx?
VSD
RCA
inferior
II, III aVF
Posterior V1, V2 (early R wave progression)
RV -> V3R-V4R (no nitrates - IVF + atropine if HR dec)
LAD
Anterioseptal V2-4
Anterior V3-5
Cirumflex
Apicolateral V5-6
Circumflex branch (OM1) or LAD branch (diag)
High lateral
I, aVL
Pt h/o CP EKG stress reveals depression in lateral leads - nuclear iaging reveals anteroseptal ischemia
High grade LAD stenosis
48yo F exertional CP, stress done - stopped in 50 min from CP and ST dep V4-6
High grade LAD stenosis
Epidemiology
900,000 deaths/yr
1/3 from CAD
smoking doubles risk
INc’d LDL and total chol risk factor
1% dec LDL = 2-3% ec risk of CAD
Every 1mm dec in BP - 2-3 % dec in r/o MI
Death rates with heart dz MORE in females
Risk factors for atherosclerosis
Modifiable HLD tob Psychocsocial stressors DM HTN Obesity Etoh Physical activity Diet low in fruits/vegies
Unmodifiable:
Age
Male
Family h/o premature CAD (LP (a))
Pt no meds - wants advice on dec’ing CAD risk - smoker, HTN, LDL 100 wtd?
Quit smoking
ACS
ST elev -> Q wave MI - TPA or PCI
NSTEMI - w+CE - ASA, plavix +- IIb/IIIa
no CE (U/A) - no TPA - hep gtt, ASA, plavix
Workup for suspected CAD - middle aged woman pw chest pain, chest discomfort or atypical CP - wtd?
EKG - if normal stress test (exc if can walk)
If pt with COPD then
Dobutamine stress (no adneosine, dyprimadole)
45yo F vague CP on exertion - EKG normal - exc stress non-sp changes - wtd?
Exc stress with imaging
If can’t walk - or non-sp ST chagnes with LBBB, LAHB, repolariz change then persantine/thallium study
Which can under EKG stress?
RBB (not LBBB or paced)
Pt with peripheral vascular dz scheduled for bypass surgery - wheezing on exam - HTN controlled to 150.90 from 170/110
Dob stress test (can’t use adenosine or dipyridamole with wheezing)
Who gets gated pool studies or MUGA scan
IN pt to dtermine LVEF and WMA (dec’d LVEF poor prognostic factor on MUGA
When NOT to do stress test
U/A
AS with sx
45yo DM2 with CP, EKG neg - test LEAST likely to be accurate is…
Exercise stress test
Obese woman with atypical CP undergoes EST - stops test after 5 min due to fatigue, no CP, HR inc’d by 50%, no EKG chagnes wtd?
Adenosine stress or stress echo
When is EST positive
Flat or down sloping ST depressions>1mm & longer than 0.08s
If ST elevated then high grade stenosis
When do you stop a stress test
ST dep >2mm
SBP dec >15mm Hg
VT
Chest pain/SOB
Poor prognostic factors on stress test
>2mm ST depression Persistant ST dep 5 min post excercise Fall in BP > 15mmHg ST elev Vent ectopy/VT global ischemic changes
Who gets cardiac cath/angiogram
Presence of poor prognostic factor on stress test
Post infarct angina
U/A on med tx still with sx or ST dep or troponin +
Unstable Angina
New onset severe angina < 2 months
Angina at rest
Recent inc’d freq
Post infarct angina
Pt with angina controlled on BB, ASA, nitrates pw inc’d freq and now chest pain lasting > 30 min -> EKG ST dep II, III, aVF - most likley mechanism for CP
Atherosclerotic plque with intermittent rupture and thomobolysis
Pt h/o chornic angina controlled on ASA, nitrates with inc freq angina wtd?
Add BB
Pt now on ASA, nitrates (with 12 hr nitrate free interval) and BB with inc’d freq angina
Check CBC for anemia
Check for infxn (in’d HR-> ischemia)
Abv pt with low Hg and EKG with ST dep - PRBC tx’d wtd?
Coronary angiogram
Pt on ASA, nitrates, BB, statin, Hg normal - no signs infxn or stress with increasing episodes angion a on exertion - angiogram MV dz not amenable to revascularization - wtd?
Ranoxazine (ranexa)
Antiplts
ASA - thromboxane
Plavix ADP
GB IIb/IIIa
Pt with CP, ST depression present
Welen’s syndrome -> persistent twi on EKG - cath lab
LMWH + GP IIb/IIIa + Plavix + ASA
If angina or ST depression perissts with or without troponin (+)
Cardiac cath
Pt stopped ASA 2 months ago 2/2 PUD - started on PPI now pw CP wtd?
start ASA
45yo M non-smoker, no DM pw new onset CP more than 1/2 hr duration while shoveling snow - no EKG changes in ER wtd?
Admit pt to chest pain unit
If CE neg, no ekg chages o/n -> stress test
65yo M woke up early AM with severe retrosernal CP x 40min, sweating, diaphoresis - EKG ST dep, Twi, started on ASA, IV nitrates BB, LMWH gpIIb/IIIa inhib - anginal pain resolves - 24 hrs later ST dep still persists
Dx: silent ischemia
Cardiac Cath pt
-> if angioplasty/PCI done - would decrease recurrent ischemia at 6 months (not reduce MI freq)
Multislice CT helpful to evaluate CP in what group of pts
Exclude dx in LOW risk patients
Exertiona dyspnea w/o chest pain in a pt may represent and anginal equivalent in absenseof pulm dz - mc seen in…
DM
Women
Elderly
Post CABG
Pathogenesis of SOB
Ischemia-> inc’d LVEDP-> Pulmonary edema
Dx: Empiric NTG or stress test or radionuclide studies
65yo with murmur MR during excercise and disappers post exc - S4 + echo shows mild hypkinesisa and EF 60% etio?
Ischemic
46yo M CP lasting 15 min - resolved in ED - HR/BP ok, no ST elev - deep Twi 1-4 - wellen’s sign wtd?
Check echo, cath
The followin gare true in pts with DM
CAD lesions are proximal
CABG better tha PTCA in pt with CAD
DM patients more likely to have silent ischemia
Among DM - more women athan men die of CAD
DM more prone to CAD than non-DM
Pt pw CP, EKG neg - Thalimum stress with reversible ischemia, cath neg dx?
microvascular angina
Tx: CCB, BB, nitrates
Elderly man with h/o syncope - EKG on prsenation normal - feels dizzy after dinner - ST dep in II, III aVF - EKG after 15 min normal dx?
Post prandial ischemia
tx: cardiac cath
Least likely to cuase ST elevation is?
Unstable angina
Transmural MI, LV aneursym post MI, acute pericarditis, Prinzmetals angina ll aan cause ST elev
Young man brought to ER with severe CP - EKG shows ST elev and MI dx - caused by which drug?
Cocaine
tx: PCI
Cardiac enzymes
Troponin - + 3-6hrs after MI
Peak 10-25hrs
Normal 5-15 days
CPK-MB + 3-8hr
Peak 10-36hrs
Normal 3 days
LDH + 8 to 18hrs
Peaks 2-3 days
Returns to normal 6-10 days
Myoglboin - 0-85= normal
inc’d immediately peaks in 1-4 hrs and normal in 24 hrs
Pt with CP, ST elv trop elevated - s/p TPA ST resolve - CP resolved - next blood draw trop more elevated wtd?
Nothing - pt who reperfused have faster peak and higher peak of trop than pt NOT perfused
Pt pw CP and ST elev - PTCA done next day has CP best marker?
Myoglobin (peaks 1-4 hrs, normal 24 hrs)
65yo M aw PNA to MICU on IV abx - EKG NSR - trop 1.3 wtd?
Echo
Low level trop see in
CHF, critial illness, LVH, coronary vasopalsm, pulm embolism, CKD
Pt pw chest pain and low BP - you suspect RV infarct - next dx step?
R EKG - V3R-V4R
Acute MI
Q wave MI and non-Q wave MI both similar long term survival
Always admit pt with new onset classic CP - relieved by SL nitro even if pt young or EKG normal
PTCA better than TPA
thrombolytics NOT given for non-Q wave MI - instead give gpIIb/IIIa inhibitors just like for U/A and ST depression
INdications for thrombolysis
Chest pain typical for infarction > 30 min with LBBB
ST elev 1mm in two continguous leads
2hrs away from PTCA center and NOT in shock
Contraindication for TPA
Absolute Prev hmorrhagic stroke Other CVA events < 1 yr IC neoplasm Active internal bleed
Relative CVA> 1 yr recent internal bleed or major trauma < 2-4 wks BP>180/110 Pregnancy Active PUD
Indications for PTCA (PCI or angioplasty)
Acute ST elev MI ST elevation with CP > 12hrs MI with shock and Pt is < 75yr STEMI post CABG pts If tPA contraindicated
Plavix
Thienopyridine ADP Plt inhibitor
Pt with MI allergic to ASA -> use plavix
Pt going for PTCA needs plavix
Pt goign for CABG - NO PLAVIX
When is CABG better than PTCA
Left Main dz
3 vessel dz with dec’d LVEF
two vessel dz with prox LAD and decreased EF
DM with CAD
Pt with CAD s/p PTCA with stent palcement - what meds on d/c
ASA + Plavix
60yo pt undergoes CABG - couple months later he is doing fine but has problems keep ing accounts occasionally
Dx: neurocognitive defect
Pt with retrosternal CP>1, diaphoretic -> EKG LBBB, ST elev in ant leads - old EKG not availabe to compaire - CK and trop pending wtd?
Cath lab
Pt with Chest pain, ST elev ant leads - s/p tPA with BP of 90/60 - 2hrs later ST elev in lateral leads BP drops to 80 pt SOB - no new murmurs - CXR pulm edema wtd?
Cath - IABP-> PIC
If allergic to ASA then desensitization
Elderly pt with IWMI gets tPA - pt becomes hypotensive and HR 38 wtd?
atropine
HR 74, BP stable, pt confused, both puils dilated - dx?
ANtichoinergic delierum
Pt with 14hrs CP, taken antacids without relief - EKG with ST elevatins in anterior leads - BP 140/80 - given ASA to chew - IV nitrates, IV BB and IV morphine - closest PTCA at least 1 hr away wtd?
Transfer for PTCA
60yo pw CP AWMI to small community hospital - nearest PTCA 2 hours away wtd?
TPA then tx for PTCA
Pt aw MI - 3 day slater Cp relieved with NTG wtd?
Cath
Pt has cath - 2 days later pain in R groin - exam with erythematous and pulsatile mass wtd?
US r/o pseduoaneurysm
Pt with MI - 9 days later with persistent CP, worse on deep breath - pericardial friction rub - CXR with effusion - EKG diffuse ST elevation with concatvity upwards
Dressler’s syndrome - secondary pericarditis
Indomethacin, ASA
Factors shownto improve survival in MI
PTCA thrombolytic therapy after Q wave MI BB ASA ACE in EF < 35%
Pt with CP, ST elev in II, III, avF all are true
ACEi improve survival
BB imporove survival
statins improve survival
(CCB DO NOT improve survival)
Pt p/w CP - AWMI tx’d in CCU wihtout complciations EF 30%, on D/C what meds
ASA, plavix, BB, ACEi, warfarin 3-6 months, Statin, ICD 40 days later - if high risk for VT then wear lifevest
65yo with angina CVABG 2ya HR BP ok, no DM, EF normal wtd to reduce chance of another cardiac event
ACEi (ramipril)
Pt had MI, stabilized - few months later stress tes ab - underwent cath - 70% Cx - started on ASA - what will inc survival?
Statin (NOT CABG or PTCA)
Complications of MI (arrythmia)
48hrs
VT (scar tissue -> need amiodarone-> ICD
NSVT
Complication of MI (ruptures)
Papillary muscle rupture -> Acute MR
Septal rupture -> Acute VSD
Free wall rupture -> Tamponade
Ventucular arrythmias during acute MI
Ventricular ectopy or NSVT during AMI should NOT be treated
VT/VFib occuring within 24 hrs of MI are independent risk factors for in house mortality BUT not risk for subsequent mortality from arrhthmia fter d/c
These DO NOT NEED long term antiarrhythmic therapy
Pt pw CP - EKG shows MI tx’d with tPA, heparin, nitrates, BB, ACEi - w/in 24 hrs pt has NSVT <30s wtd?
Observe
Mechanism of reperfusion arrhythmias?
Triggered activity; change in cardiac frequency due to accumulated Ca+
Reperfusion arrythmia
If unstable (dec’d BP, CP) - DCCV
If stable - amiodarone
wtd next - cath
Pt with NSVT reverts to SR and is otherwise uneventful - 5 days later pt ready for d/c does pt require long hterm anti arrythmic?
No
Pt with VT or VF 48hrs afte rMI - no evidence of reinfarction wtd?
tx VTACH
Vtach/VF 48 hrs after MI or more - independent risk factor for mortality after d/c - after acute tx wtd?
ICD
Pt has 2 discharges from ICD in 2 months wtd?
start amiodarone
Pt with ICD on amiodarone still getting shocks 4 months later wtd?
RF catheter ablation