Cardiology Flashcards
3 types of cardiomyopathy
- Dilated
- Hypertrophic
- Restrictive
Etiology of dilated cardiomyopathy
Idiopathic, alcoholism (thiamine deficiency), genetics, myocarditis, chemo (doxorubicin), cocaine, heroin, glue sniffing, peripartum (last trimester or within 6 mo PP)
Clinical features of dilated cardiomyopathy
- Massive enlargement of heart with all chambers dilated
- Mitral & tricuspid valve regurgitation
- L and R sided S3 and S4 sounds
- Narrow pulse pressure due to decreased stroke vol
- Arrythmias (block in bundle of His, leading to atrial and ventricular arrythmias)
- **Sudden death **
Etiology of hypertrophic cardiomyopathy
Autosomal dominant inheritance (chromo 14 missense mutation that codes for cardiac sarcomere protiens)
Clinical features of hypertrophic cardiomyopathy
- Palpitations
- Dizziness
- Angina w exercise
- SOB/DOE, CHF, arrhythmias
- Split S2, S4, harsh systolic ejection (crescendo-decrescendo) murmur best hear along lower L sternal border or apex
- Murmur best heard during valsalva
- Palpable souble apical impulse
Eitology of restrictive cardiomyopathy
- Amyloydosis, sarcoidosis
- Myocardial finrosis post open-heart surgery
- Radiation
Clinical features of restrictive cardiomyopathy
- Worsening SOB
- Progressive exercise intolerance
- Fatigue
- CHF w normal L ventricular systolic function
- Arrhythmias
- Elevated JVP
- Loud early diastolic filling sounds (S3) may be present
- Murmurs due to mitral and tricuspid regurg may be heard, but are secondary to the disease
Investigations of cardiomyopathy (all 3)
- Dilated: CBC, electrolytes, BNP, troponin, CK, CK-MB, nonspecific ST-T and Q wave changes, CXR (enlarged heart, plural effusion).
- Hypertrophic: Prominent Q wave, short PR, 2D echocardiography is diagnostic, cardiac MRI to assess severity.
- Restrictive: Normal ECG or nonsepcific ST-T wave changes, low QRS volatage, CXR mild cardiac enlargement, ventricular biopsy can determine etiology
ACS/MI
Dilated Cardiomyopathy
Hypertrophic/Obstructive Cardiomyopathy
Restrictive Cardiomyopathy
CHF (Right sided)
CHF (Left sided)
Endocarditis
Pericarditis
Rheumatic Heart Disease
Afib
Atrial flutter
Heart Block