Cardiology Flashcards
Define atherosclerosis
Combination of atheroma’s - fatty deposits - and sclerosis - hardening or stiffening - affecting medium to large arteries, caused by chronic inflammation leading to deposition of lipids and formation of plaques.
Risk factors for atherosclerosis
Age
FH
Male
Smoking
Alcohol
High sugar and fat diet low fruit and veg
Low exercise
Obesity
Poor sleep stress
Diabetes
HTN
CKD
Rheumatoid
Atypical antipsychotics
Complications of atherosclerosis
Angina
MI
TIA
Stroke
Peripheral vascular disease
Mesenteric ischaemia
Prevention of CVD
Diet, exercise and weight improvement
Stop smoking
Stop drinking
Tightly treat co-morbidities
Score the determine risk of stroke or MI in next 10 years
QRISK3 - if >10% risk, offer statin
Secondary prevention of CVD
AAAA
Aspirin
Atorvastatin
Atenolol
ACE inhibitor
Define stable angina
Narrowing of the coronary arteries such that during time of high demand, exercise, insufficient blood supply to the hear causing chest pain. Stable when symptoms are relieved by rest or GTN.
Investigations in stable angina
CT coronary angiogram - gold standard diagnostic
Physical examination
ECG
Bloods - FBC, UE, LFT, Lipid, Thyroid, HbA1c
Management of stable angina
RAMP
Refer to cardiology
Advise about diagnosis management and when to phone ambulance
Medical treatment
Procedural or surgical interventions
GTN - every 5 mins
Beta blockers, CCBs are first line
Long acting nitrites, ivabradine, nicorandil, ranolazine
2dry prevention - AAAA
Surgery - PCI, stents, balloon dilation, CABG
Define acute coronary syndrome
Term used to describe a range of conditions associated with sudden reduced blood flow to the hear.
Main types of ACS
Unstable angina
STEMI
NSTEMI
What is supplied by the Right Coronary artery
Inferior aspect
Right atrium
Right ventricle
Inferior aspect of left ventricle
Posterior aspect of septal area
What is supplied by the circumflex artery
Lateral aspect
Left atrium
Posterior aspect of the left ventricle
What is supplied by the Left anterior descending
Anterior aspect
Anterior aspect of the left ventricle
Anterior aspect of the septum
How to differentiated types of ACS
Chest pain = ECG
ST elevation - STEMI
No elevation = troponin
Raised trops +- other ECG changes - NSTEMI
Trops normal - unstable angina (or msk pain)
History of ACS
Central crushing chest pain
Nausea and vomiting
Sweating and clamminess
Feeling of impending doom
Shortness of breath
Palpitations
Pain radiates to jaw/arm
Symptoms continue at rest
Diabetic often have silent MIs - no pain
ECG changes in STEMI
ST segment elevation
New left bundle branch block
ECG changes in NSTEMI
ST depression
Deep T wave inversion
Pathological Q waves
Alternative causes for raised troponins
Chronic renal failure
Sepsis
Myocarditis
Aortic dissection
Pulmonary embolism
Investigations in ACS
Physical exam
ECG
Bloods - FBC, UE, LFT, Lipid, Thyroid, HbA1C
CXR
Echo - post event
CT coronary angiogram
Immediate management of ACS
MONA
Morphine
Oxygen (if low sats)
Aspirin 300mg
Nitrates - GTN
Management of STEMI
Primary PCI - if available within 2 hours
Thrombolysis - in PCI not available
Management of NSTEMI
BATMAN
Betablockers
Aspirin 300mg
Ticagrelor 180mg stat
Morphine
Anticoagulation - fodaparinux
Nitrates GTN
Complications of MI
Heart failure DREAD
Death
Rupture of heart septum or papillary muscles
Edema - heart failure
Arrhythmia + Aneurysm
Dressler’s Syndrome
Define Dressler’s syndrome
Also called post MI syndrome. Usually occurs 2-3 weeks post MI. Caused by local immune response and causes pericarditis. Pleuritic chest pain, low grade fever, pericardial rub , effusion./
Secondary prevention post MI
6 As
Aspirin - 75g OD
Another antiplatelet
Atorvastatin
ACE inhibitor
Atenolol
Aldosterone - if heart failue
Define left ventricular failure
The left ventricle is unable to adequately move blood throught the left side of the heart. Causes back pressure into the pulmonary system and they leak fluid causing pulmonary oedema.
Common causes of left ventricular failure
Iatrogenic - aggressive fluids in frailty
Sepsis
MI
Arrhythmia
History of left ventricular failure
Shortness of breath - worse on lying.
Cough p frothy white/pink sputum
Clinical signs of left ventricular failure
High RR
Low O2
Tachycardia
3rd heart sound
Bilateral basal crackles
Hypotension
Peripheral oedema
Investigations in left ventricular failure
ECG
ABG
CXR
Bloods - BNP
Echo
CXR findings in heart failure
ABCDE
Alveolar oedema - bat wings
Kerley B lines - interstitial oedema
Cardiomegaly
Dilated prominent upper lobe vessels/Upper lobe Diversion
Effusion
Management of left ventricular failure
Pour sod
Pour away IV fluids - fluid balance
Sit up
Oxygen
Diuretics
History of chronic heart failure
Breathlessness worse on exertion
Cough - white pink frothy sputum
Orthopnoea - SOB on lying
Paroxysmal nocturnal dyspnoea
Peripheral oedema
Management of Chronic heart failure
ABAL
ACE inhibitor
Beta Blocker
Aldosterone - when controled with A or B
Loop diuretics - furosemide for symtom management
Define Cor pulmonale
Is right sided hear failure caused by respiratory disease, increased pressure in the pulmonary arteries results in right ventricle being unable to pump effectively causing back pressure.
Common causes of Cor Pulmonale
COPD
Pulmonary embolism
Interstitial lung disease
Cystic fibrosis
Primary pulmonary hypertension
History of Cor Pulmonale
Shortness of breath - also caused by respiratory condition
Peripheral oedema
Syncope
Chest pain