Cardio Pulmonary Exam Flashcards

1
Q

Sleep apnea

A

Daytime sleepiness and objective findings of airways narrowing/obstructing at night

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2
Q

Sleep apnea hallmark

A

Airway narrow at night and collapse

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3
Q

Three types o f sleep apnea

A

central, obstructive, mixed

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4
Q

Central sleep apnea

A

altered chemosensitivity, decreased signals to respiratory muscle

Brain injury, encephalopathy

Premature infants < 40 weeks conceptual age

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5
Q

Obstructive Sleep apnea syndrome

A

repeated episodes of apnea > 10 seconds

Partial or complete pharyngeal collapse during sleep, leading to either reduction (hypopnea) or cessation (apnea) of breathing.

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6
Q

What happens do the pressure of muscles for someone who has OSAS?

A

Negative pressure during inspiration triggers a reflex which results in relaxation of pharyngeal muscles

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7
Q

What happens to the chemoreceptors for sleep apnea?

A

Dampening of the chemoreceptors during sleep, worsening the loss of airway tone

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8
Q

Classifications of Sleep Apnea:

A

● SEVERE: >30 episodes per night

● MODERATE: 15-30 episodes per night

● MILD: 5-14 episodes per night

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9
Q

sleep apnea risk factors (Adults)

A

Age, family, gender, Elevated BMI

Neck circumference:

Men greater than 17 inches
women greater than 16 inches

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10
Q

Sleep apnea risk factors (kids)

A

boys more than girls, increase CMI, african american, large adenoids or tonsils, low tone children, craniofacial abnormalities, chronic nasal obstruction

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11
Q

Signs and symptoms for adults with OSAS

A
⦿ Bed partner complaints
⦿ Sleep disturbances
⦿ Feel tired, groggy despite “sleeping” a full 8 hours
⦿ Morning headaches
⦿ Irritability
⦿ Diminished memory
⦿ Dry mouth
⦿ Car accidents
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12
Q

Signs and symptoms: children

A

Hyperactivity (primary symptom; opposite from adults)

Difficulty concentrating

Poor school performance

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13
Q

Long term consequences OSAS

A

HTN, coronary artery disease, heart failure, dysrhythmias, cerebrovascular disease (stroke, dementia, TIA, depression, erectile dysfunction)

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14
Q

Untreated OSAS have a higher death rate by how much?

A

3x higher

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15
Q

What is Obesity hypoventilation syndrome?

A

daytime hypercapnia PaCO2 > 45 mmHg and sleep disorder breathing

Altered breathing results in daytime low PaO2 and Daytime Elevated PCO2

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16
Q

Signs and symptoms hypoventilation syndrome?

A
Sleepiness
Depression
SOB with activity
Irritability
Signs of Cor Pulmonale
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17
Q

OHS risks:

A
HTN
Cor Pulmonale
Sexual dysfunction
Dysrhytmia
Polycythemia
CVA
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18
Q

Treatment of Sleep Apnea with non invasive ventilation .

A

Goal : airway stenting

Goal: increase functional residual capacity

Increases VT by 25% and decreases by 30%

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19
Q

What is functional residual capacity?

A

the volume in the lungs after a normal expiration

  • limits or decreases “de-recruitment” of alveoli
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20
Q

Continuous Positive Airway Pressure does what and how?

A

constant pressure during expiration to prevent patient from exhaling all the volume of lungs

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21
Q

Bilevel positive airway pressure

A

has two different pressures during inhale and exhale

Higher pressure during inhale for stenting

Lower pressure during exhale to facilitate blowing off of CO2

22
Q

Indications for lung transplant

A
  • Adv lung disease functional class 3/4
  • progressive lung disease
  • refractory to maximum medical intervention
  • estimate survival chance of <50% in 2 years
23
Q

Contraindications for Lung Transplant

A
  • active malignancy w/I last 2-5 years

adv and untreatable disease of any organ

significant chest wall or spine deformity

documented non compliance

Untreatable psychiatric condition

no reliable social support

susbstance abuser

24
Q

Relative contraindications for lung transplant

A

Age > 75 years

poor functional status with low potential for rehab

colonization with high resistant micro-ogranisms

obesity (BMI >30)

severe symptomatic osteoporosis mechanical ventilation

25
Lung allocation score
formulas that predict the probability of: survival in the next year without transplant, length of survival post-transplant LAS 0-100 with higher numbers indicating the patient is more likely to benefit from a lung transplant
26
LAS: factors
diagnosis, age, BMI, diabetes, functional capacity defined by NYHA, % predicted FVC, six minute walk test distance adults <400m correlated with higher mortality, mechanical vent, creatinine in blood, cardiac index, bilirubin levels, CO2 levels
27
What determination of LAS in adults?
lung transplant depends on: LAS and distance from organ
28
Lung Transplants listing: <12 years what are the main priorities ?
Medical status Blood type Size of donor/recipient Proximity of donor/recipient
29
Drugs Main Course: calcinurin inhibitors
Tacrolimus & cyclosporin
30
Drugs Main Courses: side effect
- kidney injury - HTN - Headache - Tremor - trouble shooting - high blood sugar - Electrolyte abnormalities Low magnesium, high potassium - cosmetic effects - seizures
31
Drug Side dishes:
Mycophenelate Imuran
32
Drug side dishes: common effect
mycophenelate: N/V, diarrhea, leukopenia, thrombocytopenia, anemia Imuran: leukopenia, thrombocytopenia
33
Drug salads:
They can replace main course if major side effects or more is needed Sirolimus and Everolimus
34
What is an issue with salads?
they delay wound healing
35
Bread and butter: steriods
Methylprednisolone and prednisone maintenance immunosuppression used for rejection episodes
36
What changes do you see in people with COPD?
Atrophy type 1 fibers Increased muscle fatigue lower lactic acid threshold
37
Side effect of corticosteroids?
Atrophy type 1 fibers atrophy of proximal hip and shoulder musculature
38
Cyclosporine interferes with what?
mitochondria function affecting oxidative capacity
39
As a PT to monitor effectiveness of lung transplant what are you looking into?
● oxygen saturation ● ability to clear secretions ● functional mobility ● signs of rejection
40
Normal WBC
3.9-10.7 k
41
Normal HgB
male: 14-17 g/dl female: 12-16 g/dl
42
Normal Postassium
3.5-5.0 mg/dl
43
Normal pH
7.35 - 7.45
44
Normal Pa CO2
35-45 mmHg
45
Normal Pa O2
80-100 mmHg
46
Normal HCO3
22-26 mEq/L
47
signs and symptoms of intolerance: Lower intensity
HR increases > 20-30 bpm above resting SBP increases > 20-23 mmHg increased accessory muscle use dizzy, nausea/vomit mild agitation
48
signs and symptoms of intolerance: terminate exercise
> 20% decrease in resting HR HR < 40 bpm, >130 bpm MAP < 65 , > 110 mmhg Orthostatic hypotension severe agitation RASS >2 Sedation or coma RASS < -3 SpO2 decreases 4% or 88-90% RR <5 breaths/min, >40 breaths/min, intolerable dsypnea patient discomfort
49
signs and symptoms of intolerance: ventilator - specific
ventilator alarms for disconnect FiO2 > 0.60, PEEP >10 Patient ventilator asynchrony mode of assist control tenous airway
50
In the Outpatient settings PT will monitor for rejection how?
``` ● Decrease in ex tolerance ● Decrease in microspirometry ● Signs of heart failure ● Auscultation ● Pain ● Shortness of breath, desaturation ● Medication side effects (tremors, joint aches) ● Fever ● Flu-like symptoms ```