Cardio - Cavanaugh Flashcards
Clinical signs of CHF in dogs and cats stem from what 3 major events?
- Fluid accumulation
- Low BP
- Tissue perfusion from low tissue out put
Dyspnea, tachypnea, lethargy, and syncope are main stay clinical signs of CHF in which species?
Cat
Dyspnea, tachypnea, cough, exercise intolerance, and syncope are mainstay clinical signs of CHF in which species?
Dogs
What are signs leading us to suspect L-CHF in cats?
- Cough (rare)
- Pulmonary effusion
- Pulmonary edema
2 & 3 —> due to draining into left and right atrium
What are some signs leading us to suspect R-CHF in cats?
Diarrhea (if large volume of ascites)
—>abdominal dissension
What are some signs that would lead us to suspect R-CHF in dogs?
- Pleural effusion ONLY (pleura empties into the Ratrium)
2. Diarrhea if large volume of ascites (abdominal distension)
_______ _________ (two words) is a compensatory mechanism in HF to improve cardiac output.
Sinus tachycardia
Why is spironolactone a useful drug?
- It’s a weak diuretic but K+-sparing
- It’s CARDIOPROTECTIVE (anti-fibrotic)
- Use in cases of Addison’s dz
Why would we use an ACE inhibitor?
- To decrease afterload (indirect vasodilator)
- CARDIOPROTECTIVE against myocardial fibrosis
- Combats the effects of CHRONIC RAAS activation
What are adverse effects of ACE inhibitors? When are they contraindicated?
Systemic hypotension;
Contraindicated if Pt is dehydrated or has Renal Dz (or NSAID use)
Name the drug:
Vasodilator (specifically pulmonary arteriodilator) that inhibits phosphodiesterase 5 and is used for pulmonary hypertension
Slidenafil
How would we treat ventricular tachycardia (emergency)?
Lidocaine (2mg/kg for dogs); (0.2 mg/kg for CATS)
How would we manage chronic ventricular tachycardia?
Mexiletine (PO - class 1 Na+ channel blocker)
Sotalol (PO - class 3 K+ channel blocker)
What drug can we us to treat atrial fib, supraventricular tachycardia, and myocardial relax in HCM?
DILTIAZEM: class IV Ca2+ channel blocker (0.1mg/kg IV SLOW over 5 min - in cats and dogs)
Beta blockers are great cardioprotective drugs for decreasing heart rate AND contractility. However, there’s a caveat… what is it?
ONLY give to stable patients!!
Do NOT give if they’re sick and you don’t know the underlying dz, ESPECIALLY if they have ventricular systolic dysfunction!
T or F:
Pertaining to dietary adjustments in Heart Failure, omega-3 FAs, sodium restriction, and protein restriction may be implemented to help improve the condition.
FALSE; everything is correct up until the protein restriction - they need to maintain muscle mass!
Congenital Disease characterized by volume overload (dilated eccentric hypertrophy) to LEFT side of heart.
Left (o2) —> Right (no O2) shunt!
And continuous heart murmur at Lbase - high grade!
—>check left Axillary region
—>left chamber enlargement on thor radiographs
—>turbulent flow into pulmonary artery on echo
PDA! (Dogs)
What would we see with REVERSE PDA? How do we cure it?
Severe pulmonary hypertension; not curable :(
What dog breeds are predisposed/associated with Subaortic stenosis (SAS)?
Large breeds: Goldens Newfies Rotties, Shepherds, Boxers
Concentric pressure overload in dogs with SAS is toward which side of the heart?
Left!
Upon examination of a young, large breed dog, you hear a systolic murmur at the LEFT base of the heart, near the 3-4th intercostal arch. What fits this murmur description?
SAS
In a dog with SAS, what radiographical findings would we expect?
Prominent ascending aorta + LEFT sided cardiomegaly
How do we cure SAS?
Wellll, we dont. There is no cure, but most are asymptomatic and live a normal life span.
Also, atenolol may help.
Concentric pressure overload in dogs with Pulmonic Stenosis goes toward which side of the heart?
RIGHT!
What breeds of dogs are predisposed/associated with pulmonic stenosis?
Terrier, bulldog, chihuahua, labs
Upon examination of a young dog, you hear a systolic murmur at the left base of the heart. Additional, radiographs reveal a PA bulge at 1-2 o’clock. What are these findings consistent with?
Pulmonic stenosis
Cats with ventricular septal defect (VSD) have a defect in the IV septum leading to eccentric volume overload to what 2 locations?
Lungs + LEFT side of heart
Perimembranous region “high”
In cats, what is VSD commonly seen in combination with?
Pulmonary stenosis/pulmonary hypertension
In cats with VSD, what is characteristic of the murmur?
Systolic; the smaller the defect, the LOUDER the murmur…
*no Tx if murmur is loud
Who is predisposed/associated with Tricuspid valve dysplasia?
Cats + labs
What would we see on rads if Tricuspid valve dysplasia is present?
R ventricle and atrium enlarged
In patients with tricuspid valve dysplasia, eccentric volume overload would be to which side of the heart?
RIGHT