Cardio - Anti-Angina Flashcards

1
Q

What is the drug class for Isosorbide Dinitrate?

A

The drug class for Isosorbide Dinitrate is Vasodilators: Nitrates

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2
Q

What is the MOA for Isosorbide Dinitrate?

A

The MOA for Isosorbide Dinitrate is smooth muscle dilation of attires and veins

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3
Q

What are the indications for Isosorbide Dinitrate?

A

The indications for Isosorbide Dinitrate are frequent stable angina, CHF

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4
Q

What is the drug class for Nitroglycerin?

A

The drug class for Nitroglycerin is Vasodilators: Nitrates.

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5
Q

What is the MOA for Nitroglycerin?

A

The MOA for Nitroglycerin is smooth muscle dilation of arteries and veins.

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6
Q

What are the indications for Nitroglycerin?

A

The indications for Nitroglycerin are angina, congestive heart failure.

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7
Q
What is the drug class for Dihydropyridine:
Amlodipine?
A
The drug class for Dihydropyridine:
Amlodipine is vasodilators: calcium channel blockers
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8
Q

What is the MOA for Dihydropyridine:

Amlodipine?

A

The MOA for Dihydropyridine:

Amlodipine is vasodilation due to blocking calcium channels in vascular smooth muscle and myocardium.

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9
Q

What are the indications for Dihydropyridine:

Amlodipine?

A

The indications for Dihydropyridine:

Amlodipine are angina (chronic stable and vasospastic), HTN

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10
Q
What is the drug class for Dihydropyridine:
Nifedipine?
A
The drug class for Dihydropyridine:
Nifedipine is vasodilators: calcium channel blockers
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11
Q

What is the MOA for Dihydropyridine:

Nifedipine?

A

The MOA for Dihydropyridine:

Nifedipine is vasodilation due to blocking calcium channels in vascular smooth muscle and myocardium

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12
Q

What are the indications for Dihydropyridine:

Nifedipine?

A

The indications for Dihydropyridine:

Nifedipine are angina (chronic stable and vasospastic), HTN

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13
Q
What is the drug class for Nondihydropyridine:
Diltiazem?
A
The drug class for Nondihydropyridine:
Diltiazem is vasodilators: Calcium Channel Blockers
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14
Q

What is the MOA for Nondihydropyridine:

Diltiazem?

A

The MOA for Nondihydropyridine:

Diltiazem is to dilate coronary arteries &; decrease myocardial oxygen demands

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15
Q

What are the indications for Nondihydropyridine:

Diltiazem?

A

The indications for Nondihydropyridine:

Diltiazem are angina, HTN, PSVT, A fib, A flutter

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16
Q
What is the drug class for Nondihydropyridine:
Verapamil?
A
The drug class for Nondihydropyridine:
Verapamil is vasodilators: Calcium Channel Blockers
17
Q

What is the MOA for Nondihydropyridine:

Verapamil?

A

The MOA for Nondihydropyridine:

Verapamil is to dilate coronary arteries & decrease myocardial oxygen demands

18
Q

What are the indications for Nondihydropyridine:

Verapamil?

A

The indications for Nondihydropyridine:

Verapamil are angina, HTN, PSVT, A fib, A flutter

19
Q

What is the drug class for Propranolol?

A
The drug class for Propranolol is Beta Blockers:
Nonselective  (B1 & B2)
20
Q

What are the indications for Propranolol?

A

The Indications for Propranolol is angina, HTN, tachyarrhythmias, essential tremor, migraine Px, anxiety

21
Q

What is the MOA for Propranolol?

A

The MOA for Propranolol are adrenergic B1 and B2 receptor inhibitor; reduction in myocardial oxygen demand

22
Q

What is the drug class for Metoprolol Tartrate
and
Metoprolol Succinate?

A

The drug class for Metoprolol Tartrate
and Metoprolol Succinate is Beta Blockers:
Selective (B1)

23
Q

What is the MOA for Metoprolol Tartrate

and Metoprolol Succinate?

A

The MOA for Metoprolol Tartrate

and Metoprolol Succinate is Selective B1 adrenergic receptor inhibitor

24
Q

What are the indications for Metoprolol Tartrate

and Metoprolol Succinate?

A

The indications for Metoprolol Tartrate

and Metoprolol Succinate are angina, HTN, hemodynamically stable MI

25
What is the drug class for Atenolol?
``` The drug class for Atenolol is beta Blockers: Selective (B1): ```
26
What is the MOA for Atenolol?
The MOA for Atenolol is selective B1 adrenergic receptor inhibitor
27
What are the indications for Atenolol?
The indications for Atenolol are angina, HTN, hemodynamically stable post-MI
28
What is the drug class for Carvedilol?
``` The drug class for Carvedilol is Beta Blockers: Nonselective (B1, B2, Alpha 1) ```
29
What is the MOA for Carvedilol?
The MOA for Carvedilol is Mixed alpha, beta receptor inhibition
30
What are the indications for Carvedilol?
The indications for Carvedilol are angina (off-label), HTN, stable HF, stable post-MI
31
What is the drug class for Ranolazine?
The drug class for Ranolazine is anti-anginal Agent: Miscellaneous
32
What is the MOA for Ranolazine?
The MOA for Ranolazine is that it inhibits inward sodium channel in ischemic cardiac myocytes during repolarization thereyb reducing Na+/Ca++ exchange which relaxes cardiac muscle and reduces myocyte oxygen consumption (proposed mechanism)
33
What are the indications for Ranolazine?
The indications for Ranolazine are chronic angina