Cardio Flashcards
What’s the physiology of Eisenmenger’s?
Associated with septal defects and patent DA. In a VSD, a left to right shunt exposes right ventricle to left v higher pressures, till the R ventricle hypertrophies enough that the shunt is reversed. This causes cyanosis and pulmonary hypertension.
Features of Eisenmenger’s and mx
Cyanosis, clubbing, murmur that disappears. Tx with heart-lung transplant
What is a globular heart a sign of?
ASD
What murmur does a VSD cause?
Blowing pan-systolic murmur
What psych drugs cause prolonged QT?
Anti-psychotics: haloperidol
TCAs: imipramine, noratriptylline, amitryptilline
SSRIs: citalopram
Seratonin receptor antagonists: ondansetron (also anti-emitic)
What AB can cause prolonged QT?
Erythromycin
What anti-arrhythmics can cause prolonged QT?
Amiodarone, sotalol
What electrolyte imbalances can prolong QT?
HYPOMg, Ca, K
Other causes of long QT
Hypothermia, subarachnoid haem
Mx of long QT
Beta blocker, avoid strenuous activity (can precipitate). Defib if high risk (implantable).
What investigation would you order for a patient with frequent collapse but normal resting ECG?
24 hour tape
What does long QT risk causing?
VT, then torsades (mono to polymorphic). Monomorphic VT is typically caused by MI.
Mx of VT
Adverse signs (CP, heart failure, hypotensive): immediate cardioversion. Stable: amiodarone. If drugs fail- DC shocks.
Is VT broad or narrow complex QRS?
Broad. SVT = narrow (s for small)
HOCM- demographic and inheritance pattern
Young, athletic individuals.
Autosomal dominant.
Causes thickened myocardium. LVH = reduced cardiac output.
Warfarin rules and targets for surgery
Stop warfarin 5 days prior to surgery. INR should be below 1.5.
Target for VTE and AF = 2.5
Target for recurrent VTE = 3.5
What can potentiate warfarin?
P450 inhibitors (amiodarone, ciprofloxacin).
Liver disease.
Anti-platelets.
Signs of heart failure
Third heart sound Displaced apex beat Bibasal crackles Pink, frothy sputum Raised JVP Oedema
Sx of heart failure
Sob, reduced exercise tolerance, swollen ankles/calves, fatigue.
Inv. for heart failure
ECG, bloods, BNP, echo, CX
Left V aneurysm appearance on ECG
Persistent ST elevation. Anticoagulate- stroke risk.
List complications after MI
VF (most common cause of death following CA)
Pericarditis, Dressler’s
LV Aneurysm or free wall rupture
Papillary muscle rupture (can cause mitral regurg and thus a murmur).
Cardiogenic shock
How does orlistat work?
Inhibits pancreatic and gastric lipase to reduce digestion of fat.
Unstable AF
Emergency: Immediate synchronised DC cardioversion
Bradycardia mx
Atropine 500mcg
If unsuccessful, repeat atropine or do transcutaneous pacing.
Beware of asystole.
What valve disease is PKD associated with?
Mitral valve prolapse. Beware of mitral regurg and arrhythmias
Side effects of amiodarone and baseline investigations
Pulmonary fibrosis, pneumonitis - CX
Hepatitis and fibrosis - LFTs
Thyroid issues either way- TFTs
Us and Es- can prolong QT so make sure they don’t have hypokalaemia