Cardio Flashcards
AntiHTN for blacks
CCBs
thiazide diuretics
Angioedema
Edema of dermis and mucosa (lips)
Due to insufficient Bradykinin degradation by ACE
Cause by ACEi
Thiazide diuretic MOA
Work in DCT
inhibit an-cl symporter
5% an reabsorption
Diuretic effect on heart
Decrease preload by decreased venous return
Relieve edema
Thiazide diuretic drugs
Chlorthalidone
Indapamide
Hydrochlorothiazide
Carbonic anhydride inhibitors MOA
Inhibit NaHCO3 reabsorption in PCT
TX glaucoma chf edema and altitude sickness
Carbonic anhydrase inhibitor drug
Acetazolamide
Loop diuretic MOA
Inhibit Na-K-Cl2 co transporter in thick ascending limb
25% Na reabsorption
Tx severe edema, chf, hypercalcemia and renal disease
Loop diuretic drug
Furosemide
NSAIDs and lithium decrease effectiveness
K sparing diuretics MOA
Inhibit Na influx in CT and distal tubule
1-2% Na reabsorption
K sparing diuretic drugs
Spironolactone
Triamterene
ACEi MOA
ACE inhibition and prevent bradykinin degradation for vasodilation
ACEi indication
HTN
MI
HF
diabetes
ACEi side effects
First dose hypotension
Cough
Angioedema
ACEi contraindications
Preg cat x
Hyperperfusion
Use caution with NSAIDs