Cardio Flashcards

1
Q

AntiHTN for blacks

A

CCBs

thiazide diuretics

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2
Q

Angioedema

A

Edema of dermis and mucosa (lips)
Due to insufficient Bradykinin degradation by ACE
Cause by ACEi

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3
Q

Thiazide diuretic MOA

A

Work in DCT
inhibit an-cl symporter
5% an reabsorption

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4
Q

Diuretic effect on heart

A

Decrease preload by decreased venous return

Relieve edema

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5
Q

Thiazide diuretic drugs

A

Chlorthalidone
Indapamide
Hydrochlorothiazide

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6
Q

Carbonic anhydride inhibitors MOA

A

Inhibit NaHCO3 reabsorption in PCT

TX glaucoma chf edema and altitude sickness

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7
Q

Carbonic anhydrase inhibitor drug

A

Acetazolamide

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8
Q

Loop diuretic MOA

A

Inhibit Na-K-Cl2 co transporter in thick ascending limb
25% Na reabsorption
Tx severe edema, chf, hypercalcemia and renal disease

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9
Q

Loop diuretic drug

A

Furosemide

NSAIDs and lithium decrease effectiveness

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10
Q

K sparing diuretics MOA

A

Inhibit Na influx in CT and distal tubule

1-2% Na reabsorption

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11
Q

K sparing diuretic drugs

A

Spironolactone

Triamterene

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12
Q

ACEi MOA

A

ACE inhibition and prevent bradykinin degradation for vasodilation

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13
Q

ACEi indication

A

HTN
MI
HF
diabetes

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14
Q

ACEi side effects

A

First dose hypotension
Cough
Angioedema

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15
Q

ACEi contraindications

A

Preg cat x
Hyperperfusion
Use caution with NSAIDs

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16
Q

ACEi drugs

A

Enalapril
Isinopril
Quinapril

17
Q

ARB MOA

A

Block type 1 ang II receptors

Decrease pre and after load, inhibits cardiac remodeling, promotes Na excretion, downregulates syp adrenergic activity

18
Q

ARB drugs

A

Losartan

Valsartan

19
Q

CCB drugs

A

Dihyrdopiridines
Verapamil
Diltiazem

20
Q

CCB MOA

A

Block Ca inflict into l type Ca channels in heart
Vascular Smooth muscle vasodilation
Decrease after load and contractility

21
Q

HTN drugs

A
ACEi
ARB
Beta blockers
CCBs
thiazide diuretics
22
Q

CCB adverse effects

A

Hypotension
Peripheral edema
Headache

23
Q

Beta blocker indications

A

HTN to decrease CO
Angina and MI to inhibit remodeling
Arrhythmia: increases conduction velocity and SA node automaticity

24
Q

Beta blocker contraindications

A

Asthma
AV node block
Sinus bradycardia
Unstable LV HF

25
Q

Beta blocker drugs

A
Metoprolol
Propanelol 
Carvedilol 
Atenolol
Isosorbide
26
Q

Beta blocker MOA

A

Inhibit symp stimulation
Prevent NE binding
Decrease AP propagation

27
Q

Beta blockers used in CHF

A

Metoprolol

Carvedilol

28
Q

NO fxn on CV

A
Vasodilation 
Decrease pre and after load
Decrease oxygen demand on heart 
Antithrombotic 
Anti inflammatory
29
Q

Anti arrhythmic classes

A

Class 1 sodium block phase 0
Class 2 beta
Class 3 potassium block phase 3
Class 4 calcium block phase 4

30
Q

Quinidine

A

Class 1a anti arrhythmic

For SVT

31
Q

Lidocaine

A

Class 1b anti arrhythmic

For ischemic VA

32
Q

Flecainide

A

Class 1c anti arrhythmic
Stop PVC, tx SVT. Not to be used in HF
Pro arrhythmic

33
Q

Sotalol

A

Class 3 anti arrhythmic

For VT, contraindicated in asthma