Cardio Flashcards

0
Q

RE-LY - 2009

A

Noninferiority trial

Dabigatran vs Warfarin

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1
Q

Warfarin reduces stroke risk by

A

~55%

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2
Q

AFFIRM - 2002

A

Pts w non-valvular AF
Rate vs rhythm control non-inferior,
Rhythm control shows trends towards increased mortality

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3
Q

RACE II -2010

A

Lenient (HR <80/min) in preventing cardiovascular events

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4
Q

Antiarrythmic drugs - Class I

A

NaCB
1a - procainamide, quinidine
1b - lidocaine
1c - flecanaide, propafenone

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5
Q

Anti arrhythmic drugs - Class II

A

BBs

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6
Q

Anti arrhythmic drugs - Class III

A

KCBs

Amiodarone, sotalol, dofetilide

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7
Q

Anti arrhythmic drugs - Class IV

A

CCBs

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8
Q

Digoxin

A

Na-K ATPase inhibitor: increases contractility (IC Na increases, resulting in Ca influx)
AV node blockade - increases effective refractory period, slows heartrate

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9
Q

Inotropic effect

A

+ increases myocardium contractility

- decreases myocardium contractility

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10
Q

Chronotropic effect

A

+ increases HR

- decreases HR

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11
Q

Dromotropic effect

A

+ increases AV node conduction speed

- decreases Av node conduction speed

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12
Q

Maintenance of Sinus rythtm if no Heart disease (and HTN without LVH)

A

1st choice: flecanaide, propafenone, sotalol

2nd line: amio, dofetilide, cath ablation

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13
Q

Maintenance of sinus rhythm if HTN & LVH

A

1st line: amio

2nd line: cath ablation

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14
Q

Maintenance of sinus rhythm if CAD

A

1st line: dofetilide, sotalol

2nd line: amio or cath ablation

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15
Q

Maintenance of sinus rhythm if CHF

A

1st line: amio, dofetilide

2nd line: cath ablation

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16
Q

Dronedorone

A

Amio derivate
Not in CHF
Causes GI upset
Causes incr of creatinine 2ry to decreased tubular secretion

17
Q

Complications of AF ablation

A

Stroke
PV stenosis
LA tachycardias

18
Q

SCT-HEFT

A

Pts w NYHA II/III and EF<35% mortality benefit of Prophylactic ICD

19
Q

MADIT II.

A

Post-MI w EF=< 30% mortality benefit from prophylactic ICD

20
Q

Biventricikar device Tx

A

NYHA III/IV w EF120-130 ms

NYHA I/II w LBBB QRS>130 and EF=<30%

21
Q

When to Echo a murmur?

A

All diastolic
=< 2/6 if symptoms
=> 3/6 all

22
Q

When to intervene? - MS

A

Valvuloplasty, if
Symptoms; AF; increased PAP on exercise

(Severe, if VA 60 or PAP >30 mmHg on exercise)

23
Q

When to intervene! - AS

A

AVR - if symptomatic; if asymptomatic but EF4.0m/s, mean gr >40 mmHg)

24
Q

When to intervene? - MR

A

MV repair or MVR, if symptomatic, or if LV dysfunction (ESD >= 40, EF60 cc, regurg orifice area: >= 0.4 cm2, vena contracta >= 0.7 cm)

25
Q

When to intervene? -AR

A

AVR, if symptomatic, or LV dysfunction (ESD >= 55 mm, EF0.6 mm, regurg volume >60 cc, regurg orifice area >0.3 cm2)

26
Q

Electrical alterans

A

Dg for pericardial fluid

27
Q

Electrical alterans + hemodynamical instability

A

Pericardial Tamponade

28
Q

Pericarditis

A

Rub= 2 systolic, 1 diastolic
Relieved by leaning forward
Diffuse ST-elevation & PR depression

29
Q

Constructive pericarditis

A

Kussmaul’s sign

30
Q

HOCM - incidence 1/500; no vigorous sports!!

ICD recommendations

A

Symptomatic (syncope or sudden cardiac death)

Asymptomatic high risk (family Hx of sudden cardiac death, septum >30 mm)

31
Q

A/C in pregnancy

A

1st trimester - UFH or LMWH
Then - warfarin until wk 36
At the end cont UFH drip until delivery

32
Q

Coarctation aortae

A

Distal to L subclavian
50-80% a/w bicuspid aortic valve
UE HTN
CXR: 3-sign, rib-notching

33
Q

Smoking cessation and all cause mortality in pts w IHD

A

36%

34
Q

Anti-platelet in U/A - NSTEMI if medical therapy only

A

Asa 81 mg indefinitely

Plavix 75 mg x 1/12, ideally for 1yr

35
Q

Dual antiplatelet in pt w DES

A

Asa 81 mg x indefinitely
Plavix 75 mg x min 1yr, or
Prasugrel 10 mg, or ticagrelor 90 mg bid

36
Q

Dual antiplatelet Tx for U/A or NSTEMI w BMS

A

Asa 81 mg indefinitely
Plavix 75 mg x 1/12, ideally x1yr, or
prasugrel 10 mg daily or ticagrelor 90 mg bid

37
Q

Acute MR on PA catheter

A

PCWP 25 (elevated) & v waves to 40 mmHg

38
Q

Cardiogenic shock on PA catheter

A

PCWP 25 (elevated), w CI 1.5 (decreased)

39
Q

Tamponade on PA catheter

A

Equalization of pressures:

RA 20 mmHg, PAP 40/20, PCWP 20

40
Q

VSD on PA catheter

A

Sat 88% in PA

41
Q

Pulmonary embolism on PA catheter

A

PAP 50/30,PCWP 4