Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Cardiac/Vascular/analgesics > Flashcards

Cardiac/Vascular/analgesics Flashcards

1
Q

blockes ACE from converting angiotensin 1 to angiotensin 2 leading to decrease in BP. Decrease in aldosterone production and increase in serum K levels with NA+ and fluid loss DO NOT USE WITH ARB; treatment of hypertension, HF, diabetic nephropathy, and left ventricular dysfunction after an MI (ACE inhibitor)

A

MOA of Captopril

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

hypertension, HF, diabetic nephropathy, left ventricular dysfunction after MI

A

Indications of Captopril

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

tachycardia, MI, rash, pruritus, gastric irritation, aphthous ulcers, peptic ulcers, dysgeusia, proteinuria, bone marrow suppression, cough

A

Adverse effects of Captopril

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

treatment for hypertension, diabetic nephropathy with elevated serum creatinine and proteinuria with pts with type 2 diabetes and hypertension (ARB)

A

MOA of Losartan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

hypertension, diabetic nephropathy with elevated serum creatinine and proteinuria pts with type 2 diabetes and hyper tension

A

Indications of Losartan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

dizziness, headache, diarrhea, abdominal pain. URI, cough, back pain, fever, muscle weakness, hypotension

A

Adverse effects of Losartan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

inhibits movement of calcium ions across membrane of cardiac and arterial muscle cells, depressing impulse and leaving slowed conduction, decreased MI contractibility and dilation of arteries which lowers BO and decrease myocardial oxygen consumption; treatment for hypertension in extended release form; DO NOT CRUSH

A

MOA of Diltiazem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

essential hypertension in extended release form

A

Indications of Diltiazem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

dizziness, light headedness, headache, peripheral edema, bradycardia, atrioventricular block, flushing, nausea

A

Adverse effects of Diltiazem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

acts directly on vascular smooth muscle to cause vasodilation and drop in BP, does not inhibit CV reflexes and tachycardia, renin release will occur; vasodilatior

A

MOA of Nitroprusside

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

severe hypertension, maintenance of controlled hypertension during anesthesia, acute HF

A

Indications of Nitroprusside

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

apprehension, headache, retrosternal pressure, palpitations, cyanide toxicity, diaphoresis, nausea, vomiting, abdominal pain, irritation at injection site

A

Adverse effects of Nitroprusside

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

increase intracellular calcium, and allows more calcium to enter myocardial cell during depolarization, causing positive inotropic effect (increase in contraction), increase renal perfusion with diuretic effect and decrease renin release (negative chromotropic- slower HR) and slow conduction through AV node; cardiotonic agent

A

MOA of Digoxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

HF, atrial fibrillation

A

Indications of Digoxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

headache, weakness, drowsiness, visual disturbances, arrhythmias, GI upset

A

Adverse effects of Digoxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

blocks enzyme phosphodiesterase, which leads to an increase in myocardial cell cAMP, increase calcium levels in the cell, causing stronger contractions and prolonged response to sympathetic stimulation, directly relaxes vascular smooth muscle; phosphodiesterase inhibitor

A

MOA milrinone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

short term treatment for HF in patients who do not respond to digitalis, diuretics or vasodilators

A

Indications for Milrinone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

arrythmias, hypotension, nausea, coming, thrombocytopenia, pericarditis, pleuritis, fever, chest pain, burning at injection site

A

Adverse effects of Milrinone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

competitively blocks beta-adrenergic receptors in the heart and kidney, has a membrane stabilizing effect and decreased influence on sympathetic nervous system

A

MOA of Propranolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

cardia arrhythmias, SVT, ventricular tachycardia induces by digitalis or catecholamines

A

indications of Propranolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

bradycardia, HF, arrhythmias, heart block, CVA, pulmonary edema, gastric pain, flatulence, nausea, vomiting, diarrhea, impotence, decreased exercise tolerance, antinuclear development

A

Adverse effects of Propranolol

22
Q

acts directly on the heart muscle cells to prolong repolarization and refractory period, increasing the threshold on ventricular fibrillation, also acts on peripheral smooth muscle to decrease peripheral resistance

A

MOA of Amiodarone

23
Q

treatment of life threatening ventricular arrhythmias

A

Indications of Amiodarone

24
Q

malaise, fatigue, dizziness, HF, cardiac arrhythmias, cardiac arrest, constipation, nausea, vomiting, hepatotoxicity, pulmonary toxicity, corneal microdeposits, vision changes

A

Adverse effects of Amiodarone

25
Q

binds with bile acids in the intestine, allowing excretion in the feces instead of reabsorption, causing cholesterol to be oxidized in the liver and serum cholesterol levels to fall

A

MOA of Cholestyramine

26
Q

reduction of elevated serum cholesterol in patient with primary hypercholesterolemia pruritus associated with partial biliary obstruction

A

Indications of Cholestyramine

27
Q

rash, headache, anxiety, vertigo, dizziness, constipation due to impaction, exacerbation of hemorrhoids, cramps, flatulence, nausea, increased bleeding tendencies, vit A and D deficiencies, muscle and joint pain

A

Adverse effects of Cholestyramine

28
Q

inhibits platelet aggregation by inhibiting platelet synthesis of thromboxane A2

A

MOA of aspirin

29
Q

reduction in current TIA, or history of TIA, MI prophylaxis, anti-inflammatory, analgesic, and antipyretic

A

indications of aspirin

30
Q

acute aspirin toxicity with hyperpnea, fever, coma, CV collapse, nausea, dyspepsia, heartburn, epigastric discomfort, GI bleed, occult blood loss, dizziness, tinnitus, difficult hearing, anaphylactoid reaction; anticoagulant

A

Adverse effects aspirin

31
Q

inhibit thrombus and clot production by blocking the conversion of prothrombin to thrombin and fibrinogen to fibrin

A

MOA of Heparin

32
Q

prevention and treatment of venous thrombosis or PR, treatment of AF with emboli, diagnosis and treatment of DIC, prevention of blood clotting samples and heparin lock sets

A

Indications of Heparin

33
Q

hair loss, bruising, chills, fever, osteoporosis, and suppression of renal function

A

Adverse effects of Heparin

34
Q

natural glycoprotein that stimulates RBC production in the bone marrow; erythropoiesis- stimulating agent

A

MOA of Epoetin alfa

35
Q

treatment of anemia associated with chronic renal failure related to
HIV treatment, or chemotherapy in cancer patients, to reduce the need for
allogenic blood transfusions in surgical patients

A

Indications of Epoetin alfa

36
Q

transfusions in surgical patients
ADVERSE EFFECT headache, arthralgias, fatigue, asthenia, dizziness,
hypertension, edema, chest pain, vomiting, diarrhea

A

Adverse effects of Epoetin alfa

37
Q

MOA inhibits prostaglandin synthesis by blocking COX-1 and COX-2 receptor
sites, leading to an anti-inflammatory effect, analgesia, and antipyretic

A

MOA of Ibuprofen

38
Q

signs and symptoms of rheumatoid arthritis, osteoarthritis, relief
of mild to moderate pain, dysmenorrhea, fever reduction

A

Indications of Ibuprofen

39
Q

headache, dizziness, somnolence, fatigue, rash, nausea,
dyspepsia, bleeding and constipation

A

Adverse effects of Ibuprofen

40
Q

MOA acts directly on the hypothalamus to cause vasodilation and sweating,
which will reduce fever, mechanism of action of analgesic in UNK

A

MOA of Acetaminophen

41
Q

treatment of mild to moderate pain, fever, s&S of common cold or
flu, musculoskeletal pain associated with arthritis, and rheumatic disorders

A

Indications of Acetaminophen

42
Q

rash, fever, angina, liver toxicity, renal failure, bone marrow suppression

A

Adverse effects of acetaminophen

43
Q

genetically engineered TNF receptors react with and deactivate TNF
release by active leukocytes, keeping inflammatory response in check

A

MOA of Etanercept

44
Q

reduction of s&s, improvement of function with rheumatoid
arthritis, polyarticular juvenile idiopathic arthritis, psoriatic arthritis, ankylosing
spondylitis and plaque psoriasis

A

Indications of Etanercept

45
Q

serous fatal infections, lymphoma, and other cancers,
demyelinating disorders, MI, HF, and injection site reactions

A

Adverse effects of Etanercept

46
Q

activates human cellular immunity and inhibit tumor growth through
increase in lymphocytes, platelets, and cytokines

A

MOA of Aldesleukin

47
Q

metastatic renal cell carcinoma in adults, treatment of metastatic
melanomas

A

Indications of Aldesleukin

48
Q

mental status change, dizziness, hypotension, sinus tach,
arrhythmias, pruritis, nausea, vomiting, diarrhea, anorexia, GI bleed, bone
marrow suppression, respiratory difficulties, fever, chills, pain

A

Adverse effects of Aldesleukin

49
Q

reversible inhibits immunocompetent lymphocytes, inhibits T helper cells
and t suppressor cells, lymphokine production, and release or interleukin 2 and t
cell growth factor

A

MOA of cyclosporine

50
Q

prophylaxis for organ rejection for liver, kidney and heart transplant
(with corticosteroids) treatment for chronis rejection in pts previously tested for
other immune suppression, rheumatoid arthritis, recalcitrant psoriasis

A

Indications of Cyclosporine

51
Q

tremor, hypertension, gum hyperplasia, renal dysfunction,
diarrhea, hirsutism, acne, bone marrow suppression, interleukin receptor
antagonist.

A

Adverse effects of Cyclosporine

52
Q

blocks ACE from converting angiotensin 1 to angiotensin 2 leading to decrease in BP. Decrease in aldosterone production and increase in serum K levels with NA+ and fluid loss DO NOT USE WITH ARB; treatment of hypertension, HF, diabetic nephropathy, and left ventricular dysfunction after an MI (ACE inhibitor)

A

MOA of Captopril

Pharmacology (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions