Cardiac SEE Flashcards

1
Q

What is

Inotropy
Chronotropy
Dromotropy
Lusitropy

A

Inotropy - Contractility
Chronotropy - HR
Dromotropy - Conduction velocity
Lusitropy - Myocardial relaxation during diastole

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2
Q

What is the RMP and TP of the cardiac myocyte?

A

TP, -55
RMP, -70

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3
Q

What happens to the RMP when potassium is increased or decreased

A

Decreased K - Decreases RMP
Increased K - Increases RMP

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4
Q

What is the primary determinant of TP? How does hyper/hypo affect it?

A

Ca

Increased Ca - TP becomes positive
Decreased Ca - TP becomes more negative

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5
Q

What happens when RMP becomes closer to TP? What about further away?

A

Closer - more easily depolarized
Further - Harder to depolarize

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6
Q

What is the sodium-potassium ATPase pump?

A

Restores balance towards RMP

For every 3 Na lost, 2 K enters the cell

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7
Q

What drug inhibits the Sodium-potassium ATPase pump?

A

Digoxin

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8
Q

Cardiac Conduction

A
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9
Q

What happens in phase 0 of the myocyte action potential

A

Sodium enters the ICF

(depolarization)

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10
Q

What happens in phase 1 of the myocyte action potential

A

Cl- enters the ICF
K+ leaves the ICF

(Initial repolarization)

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11
Q

What happens in phase 2 of the myocyte action potential

A

Ca+ enters and K+ leaves

(Plateau)

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12
Q

What happens in phase 3 of the myocyte action potential

A

K leaves the ICF

(Final repolarization)

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13
Q

What happens in phase 4 of the myocyte action potential

A

Resting phase

K out

Na/K/ATPase pump working

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14
Q

Between what phases is the absolute refractory period?

A

End of phase 1 to middle of phase 3

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15
Q

When is the relative refractory period?

A

End of phase 3

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16
Q

What is the conduction pathway through the heart?

A

SA node
Internodal Tracts
AV node
Bundle of HIS
Bundle branches
Purkinje fibers

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17
Q

Cardiac conduction potential

A
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18
Q

What is phase 4 of the cardiac conduction potential?

A

Spontaneous depolarization

Na in through leaky channels

Ca channels open (T type)

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19
Q

What is phase 0 of the cardiac conduction potential?

A

Depolarization

Ca enters through L channels

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20
Q

What is phase 3 of the cardiac conduction potential?

A

Repolarization

K out

21
Q

What are the RMP and TP of cardiac conduction?

A

RMP, -60
TP, -45

22
Q

What is Reynolds number? What does it signify?

A

Can predict flow

<2,000 laminar
2000-4000 transitional
>4000 turbulent

23
Q

How much does atrial kick contribute to Cardiac output?

24
Q

Wiggers Diagram

25
On the wiggers diagram when do the aortic and mitral valves open and close?
Opposite corners
26
On the wiggers diagram when does isovolumetric contraction and relaxation occur?
When the valves are closed
27
Cardiac Cycle
28
Normal EF? Severe?
Normal >50% Mild > 41-49% Moderate > 26 - 40% Severe < 25%
29
Increased Preload on diagram
30
Decreased Preload on diagram
31
Increased contractility on diagram
32
Decreased contractility on diagram
33
Increased afterload on diagram
34
Decreased afterload on diagram
35
What does the Left coronary artery divide to?
Left anterior Descending and the circumflex
36
What does the LAD perfuse? What leads?
anterolateral and apical walls of the LV and the anterior two thirds of the septum V1 V2 V3 V4
37
What does the circumflex artery perfuse? What leads?
Left atrium and posterior walls of LV Lead I aVL V5 V5
38
What does the RCA perfuse? What leads?
R atrium R ventricle II III aVF
39
What does the PDA perfuse? Where does it arise from?
inferior wall RCA
40
What does the Great Cardiac Vein drain?
LAD
41
What does the middle cardiac vein drain?
PDA
42
What does the anterior cardiac vein drain?
RCA
43
Where does almost the blood return to?
Coronary sinus
44
Cardiac Leads
45
What is the best TEE view for LV ischemia?
Midpapillary muscle level short axis
46
How much cardiac output does the coronaries get?
5%
47
What does the coronary blood flow autoregulate to?
MAP 60-140
48
What is a potent coronary vasodilator?
Adenosine (by product of ATP metabolism)
49