CARDIAC PHARMACOLOGY (HYPERTENSION) Flashcards
responsible for the conversion of ANGIOTENSIN I TO ANGIOTENSIN II
ACE- ANGIOTENSIN CONVERTING ENZYMES
responsible for regulating blood volume thus increases BP
ANGIOTENSIN II
functions of ANGIOTENSIN II
- increases sympathetic activity
- facilitates ALDOSTERONE SECRETION responsible for regulating salt and water in our body
- arteriolar vasoconstriction is present due to increase in BP caused by increase in blood volume
- facilitates ADH secretion for water retention
agent that decreases sympathetic activities and prevents vasoconstriction
a1- blockers
trade name for DOXAZOCIN
ALFADIL XL
trade name for TERAZOCIN
HYTRIN
trade name for PRAZOCIN
MINIPRESS
a1-blockers
- DOXAZOCIN
- TERAZOCIN
- PRAZOCIN
agent that decreases sympathetic activities and facilitates vasodilation
b-blockers
trade name for ALTENOLOL
CARDIOTEN
trade name for METOPROLOL
BETALOC, NEOBLOC
trade name for BISOPROLOL
BISOTEN
trade name for CARVEDILOL
DUOBLOC
b-blockers
ATENOLOL, METOPROLOL, LABETALOL, BISOPROLOL, CARVEIDILOL
reduces BP and HEART RATE
b-blockers
prevents conversion of ANGIOTENSIN I to ANGIOTENSIN II
ACE INHIBITORS
ACE INHIBITORS
BENAZEPRIL
CAPTOPRIL
ENALAPRIL
trade name for BENAZEPRIL
LOTENSIN
trade name for CAPTOPRIL
CAPOTEN
trade name for ENALAPRIL
HYPACE
prevents the binding of ANGIOTENSIN II RECEPTORS
ANGIOTENSIN RECEPTOR BLOCKERS
ANGIOTENSIN II RECEPTOR BLOCKERS
LOSARTAN VALSARTAN CANDESARTAN OLMESARTAN IRBESARTAN
trade name for LOSARTAN
COZAAR
trade name for VALSARTAN
DIOVAN
inhibition of ACE may result to
accumulation of substrates that may be harmful for the body
it is a non specific enzyme and does not only act on ANGIOTENSIN I
ACE- ANGIOTENSIN CONVERTING ENZYMES
agents that has the ability to protect the kidneys and is recommended to be taken by patients with kidney problems and hypertension
ACE & ARB
agent responsible for lowering intravascular volume by increasing water and sodium excretion
DIURETICS
it known as a weak anti-hypertensive agent and is most of the time combined with other anti-hypertensive agents
DIURETICS
DIURETICS
CHLOROTHIAZIDE
HYDROTHIAZIDE
FUROSEMIDE
SPIRONOLACTONE
trade name for FUROSEMIDE
LASIX
trade name for SPIRONOLACTONE
ALDACTONE
SE of DIURETICS
frequent urination that may be a problem for elderlies with weak sphincters
most common diuretics combined with therapy
HYDROTHIAZIDE
block Ca channel into myocardial and vascular smooth muscle cells causing it to relax
Ca CHANNEL BLOCKERS
Ca CHANNEL BLOCKERS
DILITIAZEM VERAPAMIL AMLODIPINE FELODIPINE NICARDIPINE DIFEDIPINE
trade name for DILITIAZEM
DILZEM,CARDIZEM, ANGIOZEM
trade name for VERAPAMIL
ISOPTIN
trade name for AMLODIPINE
NORVASC
trade name for FELODIPINE
PLENDIL
trade name for NICARDIPINE
CARDENE
trade name for DIFEDIPINE
PROCARDIA, ADALAT