Cardiac Muscle Flashcards
Cellular Anatomy
form a highly branched cellular network in the heart
AP in Contractile Cardiac Muscle
Na+ increases rapidly, Ca2+ comes in slowly, and K+ comes out fast
Cardiac AP Steps
Na+ influx through voltage gated Na+ channels. • Plateau caused by voltage gated (L-Type) Ca2+ channels and.... – Decrease K+ permeability • End of AP caused by K+ efflux. • Entire AP lasts ~ 200 msec.
Cardiac Muscle Contraction
occurs due to the the binding of the myosin head to adenosine triphosphate ( ATP ), which then pulls the actin filaments to the center of the sarcomere, the mechanical force of contraction.
Pacemaker Cells
Autorhythmic Cells
• Non-contractile
• No resting membrane potential
• Pacemaker potential………
Pacemaker Potentials
the slow, positive increase in voltage across the cell’s membrane (the membrane potential) that occurs between the end of one action potential and the beginning of the next action potential.
ec coupling in cardiac muscle
the process from electrical excitation of the myocyte to contraction of the heart