Cardiac and Respiratory Actions Flashcards
Adenosine (Adencard) Cardiac Drug
Class 5 Antidysrhythmic
Act: Slows conduction through the AV node; can interrupt re-entrance pathways; slow heart rate by acting directly on the sinus pacemaker cells by slowing impulse formation. The drug of choice for re-entry SVT. Can be used diagnostically for stable, wide-complex tachycardia of unknown origin after two doses of lidocaine.
ASA (Aspirin, ASA, Bayer) Cardiac Drug
Act: Prevents platelets from clumping together, or aggregating, and forming embolism
Amiodarone (cordarone, pacerone) Cardiac Drug
Class 3 Antidysrhythmic
Act: Blocks sodium channels and myocardial potassium channels, delaying re-polarization and increasing the duration of the action potential.
Atropine Cardiac Drug
Class: Anticholinergic
Act: Inhibits the action of acetylcholine at post ganglionic parasympathetic neuroeffector sites. Increases heart rate in life-threatening brady dysrhythmias.
Calcium Chloride Cardiac Drug
Act: Increases Cardiac Contractile state (positive inotropic effect). May enhance ventricular automaticity.
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Diltiazem (Cardizem) Cardiac Drug
Class 4 Antidysrhythmic
Act: Slow calcium channel blocker that blocks calcium ion influx during de-polarization of cardiac and vascular smooth muscle decreases peripheral vascular resistance and causes relaxation of the smooth muscle, resulting in a decrease of BP. reduces pre- after load or reduces myocardial oxygen demand.
Epinephrine (Adrenalin) Cardiac Drug
Class: Alpha/Beta Agonists
Act: Direct-acting alpha and beta agonist. Alpha: vasoconstriction. Beta-1 Positive Inotropic, Chronotropic, and dromotropic effects. Beta-2: bronchial smooth muscle relaxation and dilation of skeletal vasculature. Blocks histamine receptors.
Furosemide (Lasix) Cardiac Drug
Class: Diuretic
Act: Blocks the absorption of sodium and chloride at the distal and proximal tubles and the loop of Helen, causing increased urine output.
Labetalol (Normadyne, Trandate) Cardiac Drug
Class: Beta blocker
Act: BP Reduction without reflex tachycardia; total peripheral resistance reduced without significant alteration in cardiac output.
Lidocaine Hydrochloride (xylcaine) Cardiac Drug Class 1 Antidysrhythmics
Act: Decreases automaticity by slowing the rate of spontaneous phase 4 depolarization. Used for pt with ICP
Nitroglycerin (Nitrostat, Nitro-Bid, Tridill) Cardiac Drug
Act: Smooth muscle relaxant acting on vascular, bronchial, uterine, intestinal smooth muscle. dilation of arterioles and veins in the periphery. Reduced pre- and after load, decreasing workload of the heart and thereby myocardial O2 demand.
Etomidate (Amidate) Respiratory Drug
Act: Short-acting hypnotic that acts at the level of the articular activating system.
Dexamethasone Sodium Phosphate (Decadron) Respiratory Drug
Class: Corticosteroids
Act: Suppresses acute and chronic inflammation: immunosuppressive.
Albuterol (Proventil, Ventolin) Respiratory Drug
Class: Beta 2 Agonists
Act: Selective Betas-2 agonist that stimulates adrenergic receptors of the sympathomimetic nervous system. results in smooth muscle relaxation in the bronchial tree and peripheral vasculature.
Oxygen
Act: Reverses Hypoxemia
Succinycholine Chloride (Anectine) Respiratory Drug Class: Neuromuscluar blocker Depolarizing
Act: Ultra-short-acting depolarizing skeletal muscle relaxant that mimics acetylcholine as it binds with the cholinergic receptors on the motor end plates, producing a phase 1 block as manifested by fasciculations. used for pt with increase levels of K+
Rocuronium Bromide (Zemuron) Respiratory Drug Class: Neuromuscular blocker, Non -depolarizing
Act: Antagonizes acetylcholine at the motor end plates producing skeletal muscle paralysis.
Terbutaline Sulfate (Brethine) Class: Beta Agonists
Act: Selective beta-2 adrenergic receptor activity resulting in relaxation of smooth muscle of the bronchial tree and peripheral vasculature with minimal cardiac effects.
Vercuronium Bromide (Norcuron) Respiratory Drug
Act: Neuromuscular agent with intermediate duration of action that competes with acetylcholine for receptors at the motor end plate, resulting in neuromuscular blockade.
Levalbuterol (Xopenex) Respiratory Drug
Class: Beta 2 Agonists
Act: Stimulates Beta-2 receptors resulting in smooth muscle relaxation of bronchial tree and peripheral vasculature.
Methylprednisolne Sodium Succinate (Solu-Medrol) Respiratory Drug Class: Corticosteroids
Act: Highly potent synthetic glucocorticoid that suppresses acute and chronic inflammation; potentiates vascular smooth muscle relaxation by beta-adrenergic agonists.
Ipratropium (Atrovent) Respiratory Drug
Class: Anticholinergics
Act: interaction of acetylcholine at receptors sites of bronchial smooth muscle, resulting in decreased cyclic guanosine monophasphate and bronchodilation
