Cardiac Flashcards
What is the threshold of the SA node
-40mV
What is the resting potential of a ventricular fiber
-80 to -90
What is the resting membrane potential of the SA node
-55 to -60mV
The SA node is composed of what
Special cardiac muscle fibers
The SA node connects to what
Directly to the Atrial fibers
The AV node receives signal form the SA node ____ after origin
.03 seconds
How long is the signal delayed in the AV node
.09 seconds
Why is signal delayed in the AV node
due to small size of cells, low amplitude of AP, and slow rate of depolarization during excitation
How long is the final delay of signal in the penetrating bundles of the AV node
.04 seconds
How long is the overall delay from the initial origin of the signal until onset of ventricular contraction
.16 seconds
The slow conduction in the conductive system of the heart is caused mainly by ______ resulting in an increase in the ________
Diminished number of gap junctions along the pathway, resulting in an increase in the resistance to conduction
What is the resting membrane potential of the SA node fiber
-55 to -60 mV (Threshold= -40mV)
Why are fast sodium channels in the SA node already inactivated at resting potential
Inactivation gates close when membrane potential is less negative than -55mV
- The SA node fiber has a resting membrane potential of -55–60mV
Why is atrial nodal AP slower to develop than ventricular
Only slow sodium-calcium channels can open and the fast sodium channels are inactivated due to the resting potential of -55- (-60)
When do the sodium-calcium channels become activated
at -40mV
how long are the sodium-calcium channels in the SA node open
they become inactivated within 100-150msec after opening
When do the potassium channels in the SA node become open
at the same time as when the sodium-calcium channels become inactivated
How long do potassium channels remain open in the SA node
for a few tenths of a second
What is the ventricular fiber resting potential
-85 to -90
The atrial nodes do note have what two phases
phase 1 & phase 2
The AP originating in the SA node generate what
The “sinus rhythm”
What are action potentials that originate anywhere else than the SA node
Ectopic focus or pacemaker