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ISSSTE Dermatologia > Carcinoma Espinocelular y Basocelular > Flashcards

Carcinoma Espinocelular y Basocelular Flashcards

1
Q

Carcinoma basocelular (CBC)

A

Cancer mas comun
Rostro y cuello

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2
Q

Factores de riesgo CBC

A

Exposicion prolongada y acumulativa UV

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3
Q

Carcinoma espinocelular (CEC)

A

Segundo cancer de piel mas comun
Zonas fotoexpuestas

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4
Q

Diferencias en crecimiento de CEC y CBC

A

CBC crece localmente sin metastasis
CEC mayor riesgo de metastasis

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5
Q

Carcinoma basocelular mas agresivo

A

Basocelular esclerodermiforme infiltrante

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6
Q

Caracteristicas de Basocelular

A

Lesion perlada, brillante
Vasos telangiectasicos
Ulceracion central

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7
Q

Carcinoma Espinocelular con mayor riesgo metastasis

A

Perineural
Pobremente diferenciado
Localizado en mucosas

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8
Q

Lesion premaligna para Espinocelular

A

Queratosis actinica

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9
Q

Sindrome de Gorlin-Goltz

A

Autosomica dominante Gen Patched (Cromosoma 9)
Con predisposicion a formacion de Basocelular nodular

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10
Q

Dermatoscopia en CBC

A

Vasos arboreiformes, areas azul-grisaceas

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11
Q

Histopatologia en CBC

A

Celulas basaloides con palizada periferica y estroma mucinoso

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12
Q

Histopatologia en CEC

A

Queratinizacion, puente intercelulares, estructura escamosa

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13
Q

Inmunohistoquimica en CBC

A

BerEP4

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14
Q

Inmunohistoquimca en CEC

A

p63

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15
Q

Fototerapia en CBC

A

superficiales, delgados, en areas sensibles (cara)

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16
Q

Crioterapia en CBC

A

Superficiales, px no aptos a Qx
Tienen mayor riesgo de recurrencia

17
Q

Imiquimob en CBC

A

superficiales o nodulares en areas de dificil acceso

18
Q

Vismodegib en CBC

A

Inhibidor via Hedgehog, CBC avanzados, con metastasis no operables

19
Q

Margen quirurgico en CBC no agresivos

A

4-5 mm
Nodulares o Superficiales

20
Q

Margen quirurgico en CEC de alto riesgo

A

6-10 mm

21
Q

Radioterapia en CEC

A

Invasion perineural
Margenes positivos

22
Q

Bleomicina en CEC

A

Mucosas
Dificl acceso quirurgicos

23
Q

5-fluoracilo en CEC

A

Topicamente en lesiones superficiales
Precancerosas (Queratosis actinicas)

24
Q

Inhibidores PD-1 en CEC

A

Cemiplimab
No operables

25
Q
A

ISSSTE Dermatologia (6 decks)

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