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ISSSTE Dermatologia > Anticuerpos monoclonales > Flashcards

Anticuerpos monoclonales Flashcards

1
Q

Anti-TNF Antibodies

A

Adalimumab, Infliximab, Etanercept

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2
Q

IL-17 Inhibitors

A

Secukinumab, Ixekizumab, Brodalumab

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3
Q

IL-23 Inhibitors

A

Guselkumab, Tildrakizumab, Risankizumab

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4
Q

IL-12/23 Inhibitors

A

Ustekinumab

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5
Q

Anti-IgE Antibody

A

Omalizumab

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6
Q

IL-4/13 Inhibitor

A

Dupilumab

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7
Q

CD20 Inhibitor

A

Rituximab

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8
Q

Anti-C5 Complement Inhibitor

A

Eculizumab

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9
Q

IL-31 Inhibitors

A

Nemolizumab

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10
Q

Adalimumab, Infliximab, Etanercept

A

Inhibits TNF-α, reducing inflammation

Psoriasis, psoriatic arthritis, hidradenitis suppurativa

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11
Q

Secukinumab, Ixekizumab, Brodalumab

A

Blocks IL-17A or IL-17 receptor, decreasing plaque formation

Moderate-to-severe plaque psoriasis, psoriatic arthritis

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12
Q

Guselkumab, Tildrakizumab, Risankizumab

A

Targets IL-23’s p19 subunit, reducing Th17 activation

Moderate-to-severe plaque psoriasis

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13
Q

Ustekinumab

A

Targets the p40 subunit of IL-12/23, inhibiting Th1 and Th17 pathways

Moderate-to-severe psoriasis, psoriatic arthritis

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14
Q

Omalizumab

A

Binds to IgE, reducing allergic and inflammatory responses

Chronic spontaneous urticaria, atopic dermatitis

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15
Q

Dupilumab

A

Blocks IL-4 and IL-13, crucial in type 2 immune responses

Atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps

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16
Q

Rituximab

A

Targets CD20 on B cells, depleting B cells in antibody-mediated diseases

Pemphigus vulgaris, mucous membrane pemphigoid

17
Q

Eculizumab

A

Inhibits C5, preventing membrane attack complex formation

Severe bullous diseases, paroxysmal nocturnal hemoglobinuria

18
Q

Nemolizumab

A

Blocks IL-31, reducing itching and inflammation

Prurigo nodularis, atopic dermatitis

19
Q
A

ISSSTE Dermatologia (6 decks)

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